Table of Contents | Genet. Mol. Res.2013(2)
HNF1b is involved in prostate cancer risk via modulating androgenic hormone effects and coordination with other genes
Authors: Y.L. Hu, D. Zhong, F. Pang, Q.Y. Ning, Y.Y. Zhang, G. Li, J.Z. Wu and Z.N. Mo
Prostate cancer is one of the most commonly diagnosed male malignancies. Genome wide association studies have revealed HNF1b to be a major risk gene for prostate cancer susceptibility. We examined the mechanisms of involvement of HNF1b in prostate cancer development. We integrated data from Gene Expression Omnibus prostate cancer genes from the Dragon Dat.. Read More»
Genet. Mol. Res. 12(2): 2013.April.25.4
DOI: 10.4238/2013.April.25.4
Enhancement of recombinant adeno-associated virus mediated transgene expression by targeted echo-contrast agent
Authors: S.L. Yang, Y.M. Mu, K.Q. Tang, X.K. Jiang, W.K. Bai, E. Shen and B. Hu
Ultrasound-targeted microbubble destruction (UTMD) has been recently developed for destroying bubbles carrying drugs or genes, thereby permitting local release of these target molecules. We investigated whether SonoVue®, a new contrast agent that contains phospholipid-stabilized microbubbles filled with sulfur hexafluoride vapor, is effective at deliv.. Read More»
Genet. Mol. Res. 12(2): 2013.April.25.3
DOI: 10.4238/2013.April.25.3
Smallest critical region for microcephaly in a patient with mosaic ring chromosome 13
Authors: P.-H. Su, C.-P. Chen, Y.-N. Su, S.-J. Chen, L.-L. Lin and J.-Y. Chen
A ring chromosome 13 or r(13) exhibits breakage and reunion at breakage points on the long and short arms of chromosome 13, with deletions of the chromosomal segments distal to the breakage points. The r(13) chromosome accounts for approximately 20% of ring chromosomes compatible with life. We describe a female patient with mental retardation, growth reta.. Read More»
Genet. Mol. Res. 12(2): 2013.April.25.2
DOI: 10.4238/2013.April.25.2
Karyotype characterization reveals active 45S rDNA sites located on chromosome termini in Smilax rufescens (Smilacaceae)
Authors: D. Pizzaia, V.M. Oliveira, A.R. Martins, B. Appezzato-da-Gl�³ria, E. Forni-Martins and M.L.R. Aguiar-Perecin
The genus Smilax (Smilacaceae) includes species of medicinal interest; consequently, their identification is important for the control of raw material used in the manufacture of phytotherapeutic products. We investigated the karyotype of Smilax rufescens in order to look for patterns that would be useful for comparative studies of this genus. To accomplis.. Read More»
Genet. Mol. Res. 12(2): 2013.April.25.1
DOI: 10.4238/2013.April.25.1
Molecular characterization and expression analysis of the Lrh-1 gene in Chinese Hu sheep
Authors: L.H. Wang, W. Zhang, J.L. Ji, Q.X. Gao, S.H. Xiao and F. Wang
Liver receptor homologue 1 (Lrh-1) is a member of the nuclear receptor belonging to the second subfamily of the nuclear receptor family 5A (NR5A), also named NR5A2, which is important for lipid homeostasis, embryogenesis, and regulation of aromatics. The present study aimed to understand the sequence of ovine Lrh-1 and the expression traits in reproductiv.. Read More»
Genet. Mol. Res. 12(2): 2013.May.6.2
DOI: 10.4238/2013.May.6.2
Gene expression profile and enrichment pathways in different stages of bladder cancer
Authors: Z.-Q. Fang, W.-D. Zang, R. Chen, B.-W. Ye, X.-W. Wang, S.-H. Yi, W. Chen, F. He and G. Ye
Bladder cancer is a highly heterogeneous neoplasm. We examined the gene expression profile in 3 bladder cancer stages (Ta, T1, T2) using expression microarray analysis of 40 bladder tumors. Differentially expressed genes were found by the t-test, with <0.005 as the significance threshold. KEGG pathway-enrichment analysis was used to study the signaling.. Read More»
Genet. Mol. Res. 12(2): 2013.May.6.1
DOI: 10.4238/2013.May.6.1
Molecular characterization and functional analysis of the Nep1-like protein-encoding gene from Phytophthora capsici
Authors: B.Z. Feng and P.Q. Li
Phytophthora capsici is an aggressive plant pathogen that affects solanaceous and cucurbitaceous hosts. Nep1-like proteins (NLPs) are a group of effectors found particularly in oomycetes and considered important virulence factors. We identified an NLP gene (phcnlp1) from the highly virulent P. capsici strain Phyc12 that had an encoded polypeptide of 476-a.. Read More»
Genet. Mol. Res. 12(2): 2013.April.26.8
DOI: 10.4238/2013.April.26.8
Estimation of genetic parameters for growth traits in a breeding program for rainbow trout (Oncorhynchus mykiss) in China
Authors: G. Hu, W. Gu, Q.L. Bai and B.Q. Wang
Genetic parameters and breeding values for growth traits were estimated in the first and, currently, the only family selective breeding program for rainbow trout (Oncorhynchus mykiss) in China. Genetic and phenotypic data were collected for growth traits from 75 full-sibling families with a 2-generation pedigree. Genetic parameters and breeding values for.. Read More»
Genet. Mol. Res. 12(2): 2013.April.26.7
DOI: 10.4238/2013.April.26.7