Paper Highlights

Research Article   March 5, 2019
Genet. Mol. Res.: 18(2): 1-11. DOI: http://dx.doi.org/10.4238/gmr16039953

Adrenomedullin gene polymorphisms (rs4399321A/G and rs4910118C/T) in pregnancy related disorder: Preeclampsia

Preeclampsia (PE), a pregnancy specific vascular disorder which is characterized by hypertension and proteinuria is a leading cause of maternal, fetal/neonatal morbidity and mortality affecting 5-14% of pregnancies. PE is a multifactorial disorder associated with poor placentation, placental hypoxia, poor angiogenesis and excessive maternal inflammation. Adrenomedullin (ADM) is a multi.. Read More»

Research Article   March 5, 2019
Genet. Mol. Res.: 18(2): 1-27. DOI: http://dx.doi.org/10.4238/gmr16039952

Diabetes mellitus types: Key genetic determinants and risk assessment

The characteristic symptom of diabetes is consistently elevated levels of blood sugar. This is instigated either by complete lack of insulin production (type 1 diabetes), reduced level of insulin production (type 2 diabetes) or insulin resistance (inability of body cells to take up glucose). Other types of diabetes include maturity onset of diabetes of the young (MODY), a form of type 2 diabete.. Read More»

Research Article   January 5, 2019
Genet. Mol. Res.: 18(1): 1-16. DOI: http://dx.doi.org/10.4238/gmr16039948

Molecular insights of mitochondrial 16S rDNA genes of the native honey bees subspecies Apis mellifera carnica and Apis mellifera jementica (Hymenoptera: Apidae) in Saudi Arabia

The honey bee Apis mellifera is of major importance for the world’s agriculture and is also suitable for environmental monitoring. It includes several recognized subspecies distinguished by using morphological and morphometric variants. Here, 200 adult worker Apis mellifera honey bees were collected from Hail region, Saudi Arabia. Mitochondrial 16S rDNA was conducted to detect molecular p.. Read More»

Review Article   January 5, 2019
Genet. Mol. Res.: 18(1): 1-10. DOI: http://dx.doi.org/10.4238/gmr16039946

Integrative omics of ovarian cancer

Omics such as genomics, transcriptomics, proteomics, and metabolomics are gathering the study of entire characterization and molecular biology processes of organisms. The advancement in studying omics has become useful and widely applied to many human diseases. For ovarian cancer, pathogenic mechanisms at molecular levels resulting in the development of cancer are the continual debate. Due to t.. Read More»

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