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Table of contents: 2020
Plant Genetics   Research Article

Genetic inheritance of traits relating to seedling and size in ornamental pepper

Authors: Angela Maria dos Santos Pessoa, Elizanilda Ramalho do Rêgo, Michelle Gonçalves de Carvalho, Cristine Agrine Pereira dos Santos, Júlio Carlos Polimeni de Mesquita, Mailson Monteiro do Rêgo

Pepper exhibits genetic diversity and versatility in use. Knowledge of the genetic control of traits in peppers is of great importance to breeding programs given the variety of types, sizes, colors and flavors. The aim of the present study was to examine the inheritance of seedling and plant traits in ornamental pepper (Capsicum annuum). The experiment was conducted in a greenhouse in the plant.. Read More»

Genet. Mol. Res. 18(1):

Plant Genetics   Research Article

Genetic diversity, agronomic potential and reaction to downy mildew in genotypes of biofortified mini lettuce

Authors: A.C.P. Jacinto, A.J. Silveira, R. Castoldi, G.M. Maciel, A.C.S. Siquieroli and T.F.N. Mendonça, A.P. Souza, M.V. Marin, L.T. Braz

Lettuce is one of the most consumed leaf vegetables in the world, highlighting itself as a novelty in the market as mini type cultivars. During the winter the downy mildew can lead to severe damage. Thus, the objective of this work was to evaluate the genetic diversity, agronomic potential and downy mildew reaction in biofortified mini lettuce genotypes. The experiment was carried out in the Un.. Read More»

Genet. Mol. Res. 18(1):

Plant Genetics   Research Article

Super Canola: Newly Developed High Yielding, Lodging and Drought Tolerant Double Zero Cultivar of Rapeseed (Brassica napus L.)

Authors: Tariq Mahmood, Hafiz Saad Bin Mustafa, Muhammad Aftab, Qurban Ali and Arif Malik

The aim of present research was to develop a high yielding rapeseed cultivar having good quantitative and qualitative characteristics under the scenario of climate change. The research was initiated during 2005 and successfully completed during 2018 by Oilseeds Research Institute, Faisalabad Pakistan. Super Canola (RBN-13018) is an outcome of hybridization (Rainbow × RBN-03052) in 2005-06.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article

Diabetes mellitus types: Key genetic determinants and risk assessment

Authors: Dhilleswara Rao Vana, Dattatreya Adapa, Prasad VSS, Amarendranath Choudhury and Garima Ahuja

The characteristic symptom of diabetes is consistently elevated levels of blood sugar. This is instigated either by complete lack of insulin production (type 1 diabetes), reduced level of insulin production (type 2 diabetes) or insulin resistance (inability of body cells to take up glucose). Other types of diabetes include maturity onset of diabetes of the young (MODY), a form of type 2 diabete.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article

Adrenomedullin gene polymorphisms (rs4399321A/G and rs4910118C/T) in pregnancy related disorder: Preeclampsia

Authors: Goske Deepthi, Komaravalli Prasanna Latha, Vital Usharani, Prof. P. Fazul Rahman, Parveen Jahan

Preeclampsia (PE), a pregnancy specific vascular disorder which is characterized by hypertension and proteinuria is a leading cause of maternal, fetal/neonatal morbidity and mortality affecting 5-14% of pregnancies. PE is a multifactorial disorder associated with poor placentation, placental hypoxia, poor angiogenesis and excessive maternal inflammation. Adrenomedullin (ADM) is a multi.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article

Relation between MTHFR (Methylenetetrahydrofolate Reductase) gene functional polymorphisms and magnitude of Recurrent Pregnancy Losses (RPL) among women with low socio-economic status in Asian Indians

Authors: Dhatri Madduru, Supriya K, Kethora Dirsipam, Prasanna Latha Komaravalli, Syed Sayeeduddin and Parveen Jahan

The present study was intended to investigate the role of MTHFR gene functional polymorphisms, rs1801133 (C677T) and rs1801131 (A1298C) in the susceptibility and severity of Recurrent Pregnancy Losses (RPLs) in women with low socio-economic status among Asian Indians. We screened a total of 221 women that includes 102 RPL patients and 119 healthy controls. Following DNA isolat.. Read More»

Genet. Mol. Res. 18(3):

Human Genetics   Research Article

Exome Sequencing Studies for Kids with Non-Familial Food Allergy

Authors: Neda M Bogari, Amr A Amin, Husni H Rayes, Ahmed Abdelmotelb, Faisal A. Al-Allaf, Anas Dannoun, Mamdouh S Alhazmi, Saed A Basardah, Mohiuddin M Taher, Udaya Raja GK, Ashwag Aljohani, Soud Abdulraof A Khogeer, Mohamed Mahmoud Nour Eldein, Mohammad Adil, Mustafa Bogari, Imran Ali Khan, Khalid Khalaf Alharbi and Ahmed Fawzy

Introduction: Food allergies (FA) have been increasing dramatically over the past 25 years and the peanut allergy has been noticed more likely for a half-decade as well. The prevalence of FA in children was found to be 10%, which is high compared with adults. Limited periodic reports are available of numerous food allergic reactions in children. Complete exome sequencing in thi.. Read More»

Genet. Mol. Res. 18(3):

Animal Genetics   Research Article

Novel polymorphisms in the PLIN2 gene of Nellore cattle

Authors: Heloisa Defant, Ariana N Meira, Luiz L Coutinho, Luciana CA Regitano, Mirele D Poleti, Gabriel CM Moreira, Marcela Paduan, Pilar Mariani, Adhemar Zerlotini, Gerson B Mourão, Aline SM Cesar

Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers in marker assisted selection programs. An important candidate gene is perilipin 2 (PLIN2) that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid d.. Read More»

Genet. Mol. Res. 18(3):

Animal Genetics   Research Article

Genetic diversity analysis of Mongolian native cattle and other cattle breeds based on microsatellite marker

Authors: K.H. Tseveen, J.S Jung, B. Oyungerel and H.S Kong

In this study, we used genetic diversity analysis with Microsatellite (MS) markers to determine the relationships between two Mongolian native breeds (MNB) (n=78) which were compared with three foreign breeds (FB) (n=110) in Mongolia. For the analysis of genetic diversity, 11 recommended MS markers from a diversity panel conducted by the ISAG / FAO or previously reported MS markers were used. A.. Read More»

Genet. Mol. Res. 18(3):

Plant Genetics   Research Article

Identification and Characterization of Δ1-pyrroline-5-carboxylate Synthetase in Lepidium draba Plant and Investigating the Expression Level of this Gene and Some Biochemical Traits under Salt Stress

Authors: Rambod Pakzad, Kiarash Jamshidi Goharrizi, Ali Riahi-Madvar, Farzane Amirmahani, Mojtaba Mortezavi, Leila Esmaeeli

Lepidium draba, a medicinal herb belongs to the Brassicaceae family is more considered because it contains high level of glucoraphanin, as a precursor of sulforaphane (an anti-carcinogenic and anticancer agent). Whilst there has been studies on plant response to salinity stress, to date the response of L. draba to salinity stress is poorly understood. The aims of this study were Identification .. Read More»

Genet. Mol. Res. 19(1):

Animal Genetics   Research Article

Uncoupling Proteins and Cardiac Apoptosis in High Fat Diet-Fed Male Rats

Authors: K. Alsolami, Z. Alrefaie

This study aimed to assess impact of high fat diet (HFD) on cardiac apoptosis, and cardiac uncoupling proteins (UCPs) 2&3 expression. Twenty rats were fed either (45%) or (10%) fat diet for 6 months, then cardiac tissue expression of BAX, Bcl2, Fas, Fas-L (markers for apoptotic pathways) and UCP 2&3 were assessed. Results revealed enhancement of intrinsic and extrinsic cardiomyocyte apo.. Read More»

Genet. Mol. Res. 19(1):

Plant Genetics   Research Article

Genetic studies for yield and related traits in micro and macrosperma exotic lentil genotypes

Authors: Ch. Muhammad Rafiq, Sadia Kaukab, Aqsa Tahir, Masood Qadir, Busharat Hussain, Shakeel Ahmad Anwar, Muhammad Tariq Mahmood, Ali Aziz, Amir Hameed and Khalid Mehmood Mughal

With respect to seed size lentil (Lens culinaris Medikus) species usually are distributed into two main groups namely Microsperma (<2.5 g/100-seeds) with small rounded seeds and Macrosperma (>2.5 g/100-seeds) with larger and more flattened seeds. The seeds/pod and pods/plant will decrease as the seed size increases that adversely affect the seed yield. The basic aim of this study was to e.. Read More»

Genet. Mol. Res. 19(1):

Plant Genetics   Review Article

Fusarium wilt’s pathogenic studies and disease management: A review

Authors: Ch. Muhammad Rafiq, Muhammad Tariq Mahmood, Mushtaq Ahmad, Imtiaz Ali, Sadia Kaukab, Muhammad Shafiq, Muhammad Saleem, Umer Iqbal

Fusarium wilt caused by Fusarium oxysporum f. sp. ciceris is one of the most important fungal diseases of chickpea limiting its productivity in almost all chickpea growing countries across the world. F. oxysporum is soil borne and root inhabiting in nature which may survives in soil for longer period (up to six years). Pathogen undergoes asexual reproduction by producing three types of spores; .. Read More»

Genet. Mol. Res. 19(1):

Human Genetics   Research Article

Hepatitis B and C prevalence and its associated risk factors among school going children in urban and rural areas of District Muzaffar Garh, Pakistan

Authors: Sikandar Hayat, Muhammad Naeem, Arif Malik, Qurban Ali, Muhammad Khalid, Samrah Masud and Arif Mahmood Bhutta

Viral Hepatitis like hepatitis B and hepatitis C are the serious cause of mortality in Pakistan. Present study estimated the prevalence and risk factors associated with Hepatitis B and C among school going children from urban and rural areas. In urban areas overall prevalence of HBV was 5% where the highest prevalence of HBV was 80% and 20% in males and females respectively while HCV overall pr.. Read More»

Genet. Mol. Res. 19(1):

Medical Genetics   Research Article

Comparative analysis of genomic DNA extraction protocols: Maxi-preparation of quality DNA for genetic evaluation and phylogenetic studies

Authors: Muhammad Naeem, Shoaib Hassan, Samra Masud, Qurban Ali, Sikandar Hayat, Ammar Danyal Naeem and Zara Naeem

Four different DNA extraction protocols were compared for ability to produce DNA from the various tissues (caudal fin, pectoral fin, pelvic fin, muscle and gills) of three different freshwater fish species (Hypophthalmichthys molitrix, Labeo rohita and Sperata sarwari). Study describes the comparison of Phenol-chloroform; salt extraction; TNES and Urea methods in terms of ability to extract hig.. Read More»

Genet. Mol. Res. 19(1):

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