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Table of contents: 2020
Human Genetics   Research Article

Relation between MTHFR (Methylenetetrahydrofolate Reductase) gene functional polymorphisms and magnitude of Recurrent Pregnancy Losses (RPL) among women with low socio-economic status in Asian Indians

Authors: Dhatri Madduru, Supriya K, Kethora Dirsipam, Prasanna Latha Komaravalli, Syed Sayeeduddin and Parveen Jahan

The present study was intended to investigate the role of MTHFR gene functional polymorphisms, rs1801133 (C677T) and rs1801131 (A1298C) in the susceptibility and severity of Recurrent Pregnancy Losses (RPLs) in women with low socio-economic status among Asian Indians. We screened a total of 221 women that includes 102 RPL patients and 119 healthy controls. Following DNA isolat.. Read More»

Genet. Mol. Res. 18(3):

Human Genetics   Research Article

Exome Sequencing Studies for Kids with Non-Familial Food Allergy

Authors: Neda M Bogari, Amr A Amin, Husni H Rayes, Ahmed Abdelmotelb, Faisal A. Al-Allaf, Anas Dannoun, Mamdouh S Alhazmi, Saed A Basardah, Mohiuddin M Taher, Udaya Raja GK, Ashwag Aljohani, Soud Abdulraof A Khogeer, Mohamed Mahmoud Nour Eldein, Mohammad Adil, Mustafa Bogari, Imran Ali Khan, Khalid Khalaf Alharbi and Ahmed Fawzy

Introduction: Food allergies (FA) have been increasing dramatically over the past 25 years and the peanut allergy has been noticed more likely for a half-decade as well. The prevalence of FA in children was found to be 10%, which is high compared with adults. Limited periodic reports are available of numerous food allergic reactions in children. Complete exome sequencing in thi.. Read More»

Genet. Mol. Res. 18(3):

Animal Genetics   Research Article

Novel polymorphisms in the PLIN2 gene of Nellore cattle

Authors: Heloisa Defant, Ariana N Meira, Luiz L Coutinho, Luciana CA Regitano, Mirele D Poleti, Gabriel CM Moreira, Marcela Paduan, Pilar Mariani, Adhemar Zerlotini, Gerson B Mourão, Aline SM Cesar

Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers in marker assisted selection programs. An important candidate gene is perilipin 2 (PLIN2) that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid d.. Read More»

Genet. Mol. Res. 18(3):

Animal Genetics   Research Article

Genetic diversity analysis of Mongolian native cattle and other cattle breeds based on microsatellite marker

Authors: K.H. Tseveen, J.S Jung, B. Oyungerel and H.S Kong

In this study, we used genetic diversity analysis with Microsatellite (MS) markers to determine the relationships between two Mongolian native breeds (MNB) (n=78) which were compared with three foreign breeds (FB) (n=110) in Mongolia. For the analysis of genetic diversity, 11 recommended MS markers from a diversity panel conducted by the ISAG / FAO or previously reported MS markers were used. A.. Read More»

Genet. Mol. Res. 18(3):

Plant Genetics   Research Article

Knock down of molt regulating gene for development control of Helicoverpa armigera

Authors: M.N. Sharif, M.S. Iqbal, R. Alam, B. Tabassum, M.F. Awan, Q. Ali and I.A. Nasir

RNA interference (RNAi) caused by exogenous double-stranded RNA (dsRNA) is a powerful tool, and to date is widely adopted to knockdown genetic targets crucial for growth and development of agriculturally important insect pests. Helicoverpa armigera is a pest feeding on more than 30 economically important crops worldwide and a major threat. Resistance to insecticides and Bt toxins is gradually i.. Read More»

Genet. Mol. Res. 19(2):

Animal Genetics   Editorials

Editorial Highlights for Journal of Genetics and Molecular Research

Authors: Bay H

I am pleased to mention that during the year 2019, all issues of volume 18 were published online well within the time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. Genetics and Molecular Research (GMR) successfully released issues with 70 abstracts. The submissions to the journal are subjected to peer-review process by the editorial boa.. Read More»

Genet. Mol. Res. 19(2):

Human Genetics   Research Article

Targeted delivery of insulin by Psyllium plant (Plantago spaghula) based hydrogels/membranes

Authors: A.J. Sami1*, U. Ahmad1, M. Karamat1, M.N. Hafeez2,3,4 and Q. Ali5

Developments in therapeutics are the need of hour for the benefit of mankind and to increase the quality of life. Diabetes mellitus is a non-curable disease affecting a great amount of world’s population. This genetic disorder gets worse with time and ultimately leads to various complications like renal failure, lower limb amputation, heart diseases and blindness. Hydrogels for quite rece.. Read More»

Genet. Mol. Res. 19(2):

Plant Genetics   Research Article

Genetic inheritance of traits relating to seedling and size in ornamental pepper

Authors: Angela Maria dos Santos Pessoa, Elizanilda Ramalho do Rêgo, Michelle Gonçalves de Carvalho, Cristine Agrine Pereira dos Santos, Júlio Carlos Polimeni de Mesquita, Mailson Monteiro do Rêgo

Pepper exhibits genetic diversity and versatility in use. Knowledge of the genetic control of traits in peppers is of great importance to breeding programs given the variety of types, sizes, colors and flavors. The aim of the present study was to examine the inheritance of seedling and plant traits in ornamental pepper (Capsicum annuum). The experiment was conducted in a greenhouse in the plant.. Read More»

Genet. Mol. Res. 18(1):

Plant Genetics   Research Article

Genetic diversity, agronomic potential and reaction to downy mildew in genotypes of biofortified mini lettuce

Authors: A.C.P. Jacinto, A.J. Silveira, R. Castoldi, G.M. Maciel, A.C.S. Siquieroli and T.F.N. Mendonça, A.P. Souza, M.V. Marin, L.T. Braz

Lettuce is one of the most consumed leaf vegetables in the world, highlighting itself as a novelty in the market as mini type cultivars. During the winter the downy mildew can lead to severe damage. Thus, the objective of this work was to evaluate the genetic diversity, agronomic potential and downy mildew reaction in biofortified mini lettuce genotypes. The experiment was carried out in the Un.. Read More»

Genet. Mol. Res. 18(1):

Plant Genetics   Research Article

Super Canola: Newly Developed High Yielding, Lodging and Drought Tolerant Double Zero Cultivar of Rapeseed (Brassica napus L.)

Authors: Tariq Mahmood, Hafiz Saad Bin Mustafa, Muhammad Aftab, Qurban Ali and Arif Malik

The aim of present research was to develop a high yielding rapeseed cultivar having good quantitative and qualitative characteristics under the scenario of climate change. The research was initiated during 2005 and successfully completed during 2018 by Oilseeds Research Institute, Faisalabad Pakistan. Super Canola (RBN-13018) is an outcome of hybridization (Rainbow × RBN-03052) in 2005-06.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article

Diabetes mellitus types: Key genetic determinants and risk assessment

Authors: Dhilleswara Rao Vana, Dattatreya Adapa, Prasad VSS, Amarendranath Choudhury and Garima Ahuja

The characteristic symptom of diabetes is consistently elevated levels of blood sugar. This is instigated either by complete lack of insulin production (type 1 diabetes), reduced level of insulin production (type 2 diabetes) or insulin resistance (inability of body cells to take up glucose). Other types of diabetes include maturity onset of diabetes of the young (MODY), a form of type 2 diabete.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article

Adrenomedullin gene polymorphisms (rs4399321A/G and rs4910118C/T) in pregnancy related disorder: Preeclampsia

Authors: Goske Deepthi, Komaravalli Prasanna Latha, Vital Usharani, Prof. P. Fazul Rahman, Parveen Jahan

Preeclampsia (PE), a pregnancy specific vascular disorder which is characterized by hypertension and proteinuria is a leading cause of maternal, fetal/neonatal morbidity and mortality affecting 5-14% of pregnancies. PE is a multifactorial disorder associated with poor placentation, placental hypoxia, poor angiogenesis and excessive maternal inflammation. Adrenomedullin (ADM) is a multi.. Read More»

Genet. Mol. Res. 18(2):

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