Future Issues
A brief study about DNA polymerase
Authors: Mohammad irani hafeez
Ribonucleases (RNases) are key players of the host immunity and contribute to maintaining tissue homeostasis and body fluid sterility. Secreted upon a diversity of cellular injuries, they mediate signaling processes, and have been classified as alarmins. Recent literature reveals how the immune response system uses common strategies to fight both cancer and infection. RNases participate in i.. Read More»
Genet. Mol. Res. 20(6):
Mitochondrial sirtuins in cancer
Authors: Mitochondrial sirtuins in cancer
All living beings require energy and the ultimate source for this energy in eukaryotes are mitochondria – originally an organelle of bacterial origin and eventually incorporated into the cytoplasm. Mitochondrial bioenergetics and dynamics are essential for the maintenance of cellular and metabolic homeostasis and any imbalance can result in diseases such as cancer. The mitochondrial matri.. Read More»
Genet. Mol. Res. 20(6):
Optogenetic approach improves neuroregenerative potential of stem cell-based therapies
Authors: Zahra-Soheila Soheili, Hoda Shams Najafabadi
Neural cells represent very limited regenerative capacity and cannot prevent the progression of central nervous system, and retinal, neurodegenerative diseases such as Alzheimer's, Parkinson's, Retinitis pigmentosa or age related macular degeneration diseases. Stem cell based regenerative strategies revealed successful preclinical transplantation outcomes, showing that exogenous stem cell d.. Read More»
Genet. Mol. Res. 20(6):
Co-targeting the EGFR and PI3K/Akt pathway to overcome therapeutic resistance in head and neck squamous cell carcinoma: What about autophagy?
Authors: Hannah Zaryouh, Jinthe Van Loenhout, Marc Peeters, Jan Baptist,Vermorken, Filip Lardon, An Wouters
Recent insights in the PI3K/Akt pathway as a promising therapeutic target in combination with EGFR-targeting agents to treat head and neck squamous cell carcinoma. The Epidermal Growth Factor Receptor (EGFR) is overexpressed in the majority of Head and Neck Squamous Cell Carcinomas (HNSCC). This triggered the development of multiple anti-EGFR agents as a potential tre.. Read More»
Genet. Mol. Res. 20(6):
Genetic diversity and structure in Tunisian wild cherries and cultivated sweet cherries revealed by SSR markers
Authors: Azizi-Gannouni Thouraya, Ammari Youssef, Mnasri Rahmani Sameh, Ben Naceur M’barek, Albouchi Ali
Wild cherries are concentrated at high altitudes in northern Tunisia and cultivated sweet cherries are well adapted to low altitudes. This study aims to compare local wild and cultivated sweet cherries (Prunus avium L.) in the northern of Tunisia. To elucidate genetic variation of 21 cultivated sweet cherries (one landrace and 20 foreigner cultivars) and 4 local wild sweet cherries, we used.. Read More»
Genet. Mol. Res. 20(6):
Genital infections in females
Authors: Kazuki Sakai
Most ladies experience minor vaginal issues now and again. These issues can be identified with monthly cycles, sex, contamination, conception prevention techniques, maturing, medications, or changes after pregnancy. An adjustment in your typical vaginal release might be the principal indication of a vaginal issue. Changes in pee, for example, peeing all the more often or having a consuming incl.. Read More»
Genet. Mol. Res. 20(2):
Genetic Variability, Heritability and Genetic Advance in Bread Wheat
Authors: J. Prasad, A. Dasora, D. Chauhan, D.A. Rizzardi, S. K. Bangarwa, K. Nesara
The Present investigation was carried out using 50 bread wheat genotypes at Instructional Farm, Rajasthan College of Agriculture, Udaipur during Rabi, 2019-2020 in randomized block design with three replications. Analysis of variance revealed significant difference between genotypes for all the characters studied. Sufficient variability was present in the genotypes under study for all the chara.. Read More»
Genet. Mol. Res. 20(2):
Analysis of micro-RNAs and gene expression profiles in gestational diabetes mellitus
Authors: R. Bhushan, P. K. Dubey
Gestational diabetes mellitus (GDM) is a metabolic disorder characterized by insulin resistance. Lack of complete mechanisms involved in its pathophysiology makes its early diagnosis and treatment a difficult task. Recently, micro-RNAs are associated with many diseases including GDM. Its high stability in biological fluids and the ability to modulate genes at large scale makes it potent bio-mar.. Read More»
Genet. Mol. Res. 20(2):
Expression analysis of tocopherol key genes during seed development
Authors: A. Jai-uean, P. Sangin
Cleome viscosa (Cv) Linn is an annual oilseed crop plant that has high vitamin E, with the most active form represented as the tocopherols (α, β, γ and δ). These act as antioxidants in plants and are also essential components for human health. The gene expression profiles and partial-length cDNA encoding tocopherol cyclase (CvVTE1), homogentisic acid prenyltransferase (Cv.. Read More»
Genet. Mol. Res. 20(2):
Investigation the possibility of simple sequence repeats for generating a phase variation
Authors: Mohammad Abdul Rahmman Al-Maeni, Shaymaa Fouad Rasheed AlKhazraji
Phase variation mediating simple sequence repeat (SSR) in sipped strand mispairing is considered the most important mechanisms of genetic variation in N. meningitidis and in defense against host attack strategies despite elicitation of the immune system against commensal and pathogenic bacteria. We aimed to achieve in a silico study for determining the possibility of SSR within different positi.. Read More»
Genet. Mol. Res. 20(2):
Inheritance: A basic phenomenon in genetics
Authors: Suman Dhawan
Genet. Mol. Res. 20(3):
Genetic code: A major tool for DNA sequencing
Authors: Vinay Gupta
Genet. Mol. Res. 20(3):
A brief study on Operon model
Authors: Steve Johnson
Genet. Mol. Res. 20(3):
A spectrometrical study on Proteomics
Authors: Francis Jacob
Genet. Mol. Res. 20(3):
Lac operon: It's structure and function
Authors: Stephan Morris*
Early bits of knowledge into components of transcriptional guideline came from investigations of E. coli by scientists Francois Jacob and Jacques Monod. In E. coli, and numerous different microscopic organisms, qualities encoding a few distinct proteins might be situated on a solitary record unit called an operon. The qualities in an operon share the equivalent transcriptional guideline, yet ar.. Read More»
Genet. Mol. Res. 20(4):
DNA replication: Process in Eukaryotes
Authors: Harsh Pandey*
Genet. Mol. Res. 20(4):
A brief study on molecular sensors
Authors: Jack Hamilton*
Genet. Mol. Res. 20(4):
A brief note on chromosomal abberation
Authors: Gerome Taylor*
Genet. Mol. Res. 20(4):
Fungal cell wall components are unique antifungal target
Authors: Chibuike Ibe
Fungal cell wall is absent in mammalian cell. In fungal the cell wall is fused to the cell physiology playing a crucial role in the entire cell functionality.. The cell wall components are synthesised and modified in the cell wall space by the actions of cell wall proteins through a range of signalling pathways that are all unique to fungi, thus making the cell wall and its components suitable .. Read More»
Genet. Mol. Res. 20(5):
Probiotic potential of novel Brazilian Lactobacillus crispatus strains
Authors: Vasco Azevedo
Lactobacilli are predominant bacterial species colonizing the vaginal surfaces of healthy women, where they play a protective role against opportunistic and polymicrobial infections such as Bacterial Vaginosis (BV). Several Lactobacillus species, especially L. crispatus, have been prospected for probiotic applications due to their potential antimicrobial and anti-inflammatory capacity. In the l.. Read More»
Genet. Mol. Res. 20(5):
A brief study about reverse transcriptase
Authors: Steven Anderson
Genet. Mol. Res. 20(5):
A brief study about DNA Polymerase
Authors: Stella Andrews
Genet. Mol. Res. 20(5):
