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Investigation the possibility of simple sequence repeats for generating a phase variation

Author(s): Mohammad Abdul Rahmman Al-Maeni, Shaymaa Fouad Rasheed AlKhazraji

Phase variation mediating simple sequence repeat (SSR) in sipped strand mispairing is considered the most important mechanisms of genetic variation in N. meningitidis and in defense against host attack strategies despite elicitation of the immune system against commensal and pathogenic bacteria. We aimed to achieve in a silico study for determining the possibility of SSR within different positions of N. meningitidis genome to enroll within a phase variation mechanism.