Medical Genetics
Genetic Advances and Heritability for Different Seedling Traits of Wheat and Maize under Heavy Metal and Salt Stress
Authors: K. Afzal, M.S. Rashid, Q. Ali and A. Malik
Maize (Zea mays) and wheat (Triticum aestivum) both are an important cereal crop plants. Both are grown as food and feed for human and livestock. Wheat and maize are highly sensitive to heat, drought, salinity and heavy metal toxicity. For evaluation of genotypes of maize and wheat under heavy metal and salt stress, an experimented was conducted in the gr.. Read More»
- Genet. Mol. Res. 19(3):
Genetic Evaluation of Brassica juncea and Sinapis alba Seedling Traits under Multi Stress Conditions
Authors: H. Khan, M.S. Rashid, Q. Ali and A. Malik
Brassica is an important oil seed crop plant species grown throughout the world. Brassica juncea and Sinapis alba are very sensitive to abiotic stress conditions which included drought, heat, salt, heavy metals and cold which disturb their growth and yield. For this purpose to check the effect of heavy metals, salt and drought, an experiment was conducted.. Read More»
- Genet. Mol. Res. 19(3):
Genetic Advances and Heritability Analysis for Seedling Growth Traits in Zea mays under Heavy Metal Stress
Authors: A. Ashraf, M.S. Rashid, Q. Ali and A. Malik
Maize (Zea mays L.) is an important cereal crop grown throughout the world for its grain and fodder. Maize is very sensitive to salt, drought, heavy metal and cold stress conditions. An experiment was conducted in the green house of Institute of Molecular Biology and Biotechnology, The University of Lahore. EV-1097Q and B-316 maize genotypes were selected.. Read More»
- Genet. Mol. Res. 19(3):
Stability Investigation and Genotype Ã?Â? Environment Association in Chickpea Genotypes Utilizing AMMI And GGE Biplot Model
Authors: M.G. Azam, M.S. Iqba, M.A. Hossain and M.F. Hossain
Chickpea (Cicer arietinum L.) is generally grown-up underneath rainfed conditions inside the Barind space in Bangladesh, any place drought spell is that the principle production constraint. Genotype × Environment Interaction (GEI) was acclimated with making estimation of the grain yield and to get a handle on the G × E connection designs by an.. Read More»
- Genet. Mol. Res. 19(3):
Comparative analysis of genomic DNA extraction protocols: Maxi-preparation of quality DNA for genetic evaluation and phylogenetic studies
Authors: Muhammad Naeem, Shoaib Hassan, Samra Masud, Qurban Ali, Sikandar Hayat, Ammar Danyal Naeem and Zara Naeem
Four different DNA extraction protocols were compared for ability to produce DNA from the various tissues (caudal fin, pectoral fin, pelvic fin, muscle and gills) of three different freshwater fish species (Hypophthalmichthys molitrix, Labeo rohita and Sperata sarwari). Study describes the comparison of Phenol-chloroform; salt extraction.. Read More»
- Genet. Mol. Res. 19(1):
Expression of HCN and sodium channels in murine model of Type I diabetes
Authors: Anantha Maharasi Rama Krishnan and Kavitha Sankaranarayanan
Pancreatic apoptosis is an important event in the pathogenesis of Type 1 Diabetes. It is characterized by secretion and binding of inflammatory cytokines to the pancreatic islets, that activate downstream signaling mechanism. These signaling mechanisms finally increase intracellular calcium level and that lead to the activation of apoptotic pathways. Ion .. Read More»
- Genet. Mol. Res. 18(2):
Possible association of proinflammatory cytokine IL-19 gene polymorphism with psoriasis
Authors: Wani Aadil, Bashir Ahmad Ganai, Tahseena Akhtar Tarun Narang, Rajinder Kaur
Background: Interleukin (IL-19) a member of the IL-10 family involved in abnormal keratinocyte differentiation and proliferation which is the hall mark of psoriasis. Aim: The aim of this study was to investigate the association between IL-19 gene polymorphism in patients with chronic plaque psoriasis as a factor in the susceptibility and developme.. Read More»
- Genet. Mol. Res. 18(1):
Expression analysis of OIP5-AS1 in bladder tissues
Authors: Feraydoon Abdolmaleki, Soudeh Ghafoui-Fard, Mohammad Taheri, Alireza Mordadi, Mandana Afasharpad, Abolghasem Nikfallah, Bashir Nazparvar, Vahid Kholghi Oskooei, Mir Davood Omrani
Long non-coding RNAs (lncRNAs) have crucial roles in regulation of many aspects of cell functions which are related with carcinogenesis process. The lncRNA Opa Interacting Protein 5-antisense 1 (OIP5-AS1) is among lncRNAs whose roles in some human malignancies have been elucidated. In the current study, we aimed at identification of the role of this lncRN.. Read More»
- Genet. Mol. Res. 18(1):
The clinical significance of miR-7-5p downregulation in gastric dysplasia and gastric cancer tissue
Authors: Sara Omrani, Ali Zare, Shahriar Tarighi, Hamid Ghaedi, Mir Davood Omrani
miRNAs have been involved in the pathogenesis of several cancers such as gastric cancer (GC.). In the following study we analyzed the expression of miR-7 in gastric cancer samples compared non-tumor tissues and gastric dysplasia (GD) samples with patients’ clinico-pathological data and its potential as diagnostic biomarker. We first analyzed its exp.. Read More»
- Genet. Mol. Res. 18(4):
NNT and NNT-AS1 expression levels are not different between bipolar patients and healthy subjects
Authors: Soudeh Ghafouri-Fard, Mohammad Taheri, Vahid Kholghi Oskooie, Mir Davood Omrani, Arezou Sayad
Nicotinamide nucleotide transhydrogenase (NNT) participates in redox and energy interconnections. Nnt silencing in N27 dopaminergic cells has changed basal, extra, and greatest mitochondrial oxygen absorption rates and made these cell vulnerable to constant upsurges in H2O2. NNT-antisense RNA1 (NNT-AS1) is transcribed from the opposite stand of NNT gene a.. Read More»
- Genet. Mol. Res. 18(1):