Medical Genetics
Differential expression of glypican-3 (GPC3) in lung squamous cell carcinoma and lung adenocarcinoma and its clinical significance
Authors: X. Yu, Y. Li, S.W. Chen, Y. Shi and F. Xu
In this study, we examined the expression of glypican-3 (GPC3) in the 2 most common histological types of lung cancer, squamous cell carcinoma and adenocarcinoma, and explored the relationship between GPC3 expression and the prognosis of these 2 types of lung cancers. Lung cancer tissues and paracancerous tissues were collected from a total of 60 patients.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.2
- DOI:
- 10.4238/2015.August.28.2
PPAR�³ Pro12Ala and His447His polymorphisms and susceptibility to Alzheimerâ��s disease: a meta-analysis
Authors: Y.H. Lee and G.G. Song
We investigated whether Pro12Ala (C→G) and His447His (C→T) polymorphisms of the peroxisome proliferatoractivated receptor gamma (PPARg) gene are associated with susceptibility to Alzheimer’s disease (AD). We conducted a metaanalysis of the associations between the PPARg Pro12Ala and His447His polymorphisms and AD in subjects. The meta-anal.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.18
- DOI:
- 10.4238/2015.June.29.18
Genotoxic evaluation of the organophosphorous pesticide temephos
Authors: Cl�¡udia Alessandra Fortes Aiub, Elis�¢ngela Cristina Alves Coelho, Eduardo Sodr�©, Luis Felipe Ribeiro Pinto and Israel Felzenszwalb
The chemical compound temephos (0,0,0',0'-tetrametyl-0,0'-thiodi-p-phenylene phosphorothioate) is an organophosphorous pesticide that has been used in Brazil since 1967 in control campaigns against the mosquito Aedes aegypti, the vector of dengue and yellow fever. We used single cell gel electrophoresis (SCGE), SOS/umu and Ame.. Read More»
- Genet. Mol. Res. 1(2):