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Medical Genetics

Medical Genetics   Research Article

PPAR�³ Pro12Ala and His447His polymorphisms and susceptibility to Alzheimerâ��s disease: a meta-analysis

Authors: Y.H. Lee and G.G. Song

We investigated whether Pro12Ala (C→G) and His447His (C→T) polymorphisms of the peroxisome proliferatoractivated receptor gamma (PPARg) gene are associated with susceptibility to Alzheimer’s disease (AD). We conducted a metaanalysis of the associations between the PPARg Pro12Ala and His447His polymorphisms and AD in subjects. The meta-anal.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.18
DOI:
10.4238/2015.June.29.18
Medical Genetics   Research Article

Genotoxic evaluation of the organophosphorous pesticide temephos

Authors: Cl�¡udia Alessandra Fortes Aiub, Elis�¢ngela Cristina Alves Coelho, Eduardo Sodr�©, Luis Felipe Ribeiro Pinto and Israel Felzenszwalb

The chemical compound temephos (0,0,0',0'-tetrametyl-0,0'-thiodi-p-phenylene phosphorothioate) is an organophosphorous pesticide that has been used in Brazil since 1967 in control campaigns against the mosquito Aedes aegypti, the vector of dengue and yellow fever. We used single cell gel electrophoresis (SCGE), SOS/umu and Ame.. Read More»

Genet. Mol. Res. 1(2):