Medical Genetics

Precision medicine: Tailoring treatment through genetics

Authors: Janneke Aylward

Genet. Mol. Res. 22(1):

RNA interference (RNAi): Harnessing molecular mechanisms for therapeutic applications

Authors: Elli Toivonen

Genet. Mol. Res. 21(1):

The intersection of genetics and artificial intelligence: Accelerating discovery and innovation

Authors: Xavier De La Cruz

Genet. Mol. Res. 21(1):

An Editorial on Antibiotic resistance from Arbitrary DNA Sequences

Authors: M. Akram

Anti-infection obstruction is a significant worldwide issue and the spread of safe microorganisms causes sickness and passing and comprises a significant expense to society. The most widely recognized path for microscopic organisms to create opposition is by taking up different sorts of obstruction qualities from different microorganisms. These qualities .. Read More»

Genet. Mol. Res. 20(1):

Analysis of Micro-RNAs and Gene Expression Profiles in Gestational Diabetes Mellitus: A Consensus Approach

Authors: R. Bhushan, A. Rani, D. Gupta, I. Khan, A. Tripati, R. P. Singh and K. D. Pawan

Gestational Diabetes Mellitus (GDM) is a metabolic disorder characterized by insulin resistance. Lack of complete mechanisms involved in its pathophysiology makes its early diagnosis and treatment a difficult task. Recently, micro-RNAs are associated with many diseases including GDM. Its high stability in biological fluids and the ability to modulate gene.. Read More»

Genet. Mol. Res. 20(1):

Diagnosis of Idiopathic Primary Infertility in a Consanguineous Infertile Family using Clinical and Molecular Cytogenetic Techniques

Authors: H. Muhammad, R. Khan, F. Wahab, I. Khan, B. Shah, A. Ali, N. Farooqi, Dil, N. Ali, F. Jalil and S. Ali

Background: Male infertility is a multifactorial medical problem affecting around 7% of the male population in whom 1% are affected by Non Obstructive Azoospermia (NOA). Despite of advanced diagnostic techniques, majority of the infertility cases remain idiopathic .Therefore more evidence based scientific research is required to investigate the underlying.. Read More»

Genet. Mol. Res. 19(5):

Development and Transferability of Microsatellites Markers for Species of the Saltans Group of Drosophila (Diptera: Drosophilidae)

Authors: B.E. Roman, B.M. Trava and L. Madi-Ravazzi

The microsatellite markers (SSRs) are highly polymorphic, fast evolving, and regarded as neutral markers. Due to these traits, they have been widely used in population studies. The development of specific SSRs for a given species opens possibilities for the application, by means of transferability, in population studies of other species that are phylogene.. Read More»

Genet. Mol. Res. 19(4):

Molecular Characterization of Tuf Gene and Antibiotic Susceptibility Patterns of Streptococcus Species in Local Population of Lahore, Pakistan

Authors: A. Mahmood, A. J. Sami and Q. Ali

Background: Multi Drug Resistance (MDR) is a global problem which is expeditiously increasing. Different antimicrobial drugs have been reported resistant against various Streptococcus species. This has been a threat to local individuals in all over the world specifically in developing countries including Pakistan. Decreased efficiency of drugs due to emer.. Read More»

Genet. Mol. Res. 19(4):

Knock down of molt regulating gene for development control of Helicoverpa armigera

Authors: M.N. Sharif, M.S. Iqbal, R. Alam, B. Tabassum, M.F. Awan, Q. Ali and I.A. Nasir

RNA interference (RNAi) caused by exogenous double-stranded RNA (dsRNA) is a powerful tool, and to date is widely adopted to knockdown genetic targets crucial for growth and development of agriculturally important insect pests. Helicoverpa armigera is a pest feeding on more than 30 economically important crops worldwide and a major threat. Resistance to i.. Read More»

Genet. Mol. Res. 19(2):

Genetic Evaluation for Effects of Salt and Drought Stress on Growth Traits of Zea mays Seedlings

Authors: M. Khalil, M.S. Rashid, Q. Ali and A. Malik

Maize is an important grain cash crop grown throughout the world for its grain and fodder. It is highly sensitive for abiotic stress conditions; like drought, chilling, alkalinity, heat, salt and cold conditions. Present study was carried out to find out the effects of salt or NaCl and drought stress on three selected maize genotypes viz., P6103, L5971 an.. Read More»

Genet. Mol. Res. 19(3):