Medical Genetics
Clinical application of carbon nanoparticle lymph node tracer in the VI region lymph node dissection of differentiated thyroid cancer
Authors: S.P. Sun, Y. Zhang, Z.Q. Cui, Q. Chen, W. Zhang, C.X. Zhou, P.P. Xie and B.G. Liu
The application and clinical significance of carbon nanoparticle lymph tracer in the VI region (central region) lymph node dissection of differentiated thyroid cancer was investigated. Eighty patients with differentiated thyroid cancer were equally divided into the carbon nanoparticle-marked group (ipsilateral thyroid injectio.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.4
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.4
Bibliometric network analysis of glaucoma
Authors: L.-Y. Dong, M. Yin and X.-L. Kang
Elevated intraocular pressure is recognized as the principal risk factor for development of optic nerve head (ONH) injury. Lamina cribrosa (LC) cells and astrocytes are two types of cells in the ONH. We attempted to identify more target genes and predict their underlying molecular mechanisms. In this study, we performed meta-analysis of the data from two .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.1
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.1
Ginsenoside Rh2 promotes nonamyloidgenic cleavage of amyloid precursor protein via a cholesterol-dependent pathway
Authors: J. Qiu, W. Li, S.H. Feng, M. Wang and Z.Y. He
Ginsenoside Rh2 (Rh2) is a ginseng derivative used in Chinese traditional medicine. We investigated whether Rh2 can help prevent Alzheimer’s disease symptoms and examined underlying mechanisms. We injected Rh2 into tg2576 Alzheimer’s disease model mice and looked for behavioral improvement and senile plaque reducti.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.2
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.2
Endophytic bacteria from banana cultivars and their antifungal activity
Authors: A. Souza1, J.C. Cruz2, N.R. Sousa2, A.R.L. Proc�?³pio1 and G.F. Silva2
Endophytic microorganisms consist of fungi, bacteria, and actinomycetes that play important roles in the process of plant adaptation to the environment. Currently, the natural associations between microorganisms and plant species are being explored for a large number of biotechnological applications. In this study, 122 endophytic bacteria were isolated fr.. Read More»
- Genet. Mol. Res. 13(4):
Clinical value of surfactant protein-A in serum and sputum for pulmonary tuberculosis diagnosis
Authors: H. Hu, G.L. Teng, L.Z. Gai, Y. Yang and C.J. Zhu
The aim of this study was to explore the diagnostic and differential diagnosis value of surfactant protein-A (SP-A) in the serum and sputum for pulmonary tuberculosis. A total of 101 patients with pulmonary tuberculosis, 85 healthy volunteers, and 30 chronic obstructive pulmonary disease (COPD) patients were divided into pulmonary tuberculosis group, heal.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.2
- DOI:
- 10.4238/2013.October.24.2
Long-term survival of non-small-cell lung cancer patients with EGFR inhibitor treatment
Authors: M.X. Zhang1,2, W. Tan1, R.X. Zhang3, Y.L. Tian1, H.M. Gao1,2, Z. Gao1, N. Zhang1, J.Q. Zhao1, Y.F. Jia1,2 and Y.S. Wang1,2
The epidermal growth factor receptor (EGFR) inhibitors gefitinib and erlotinib are effective in the treatment of advanced non-small-cell lung cancer (NSCLC), but the median survival of patients is short. Here, we describe 2 patients with NSCLC receiving conventional chemotherapy and alternative treatment with gefitinib or erlotinib as second-line therapy... Read More»
- Genet. Mol. Res. 13(4):
Preset ureter catheter in laparoscopic radical hysterectomy of cervical cancer
Authors: L. Han, R. Cao, J.Y. Jiang, Y. Xi, X.C. Li and G.H. Yu
The aim of this study was to evaluate the clinical efficacy of a temporary ureteral catheter in preventing iatrogenic ureteral damage in cervical cancer patients undergoing laparoscopic radical hysterectomy. All cases had confirmed diagnoses of cervical cancer preoperatively between December 2008 and December 2012 in our hospi.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.6
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.6
De novo DNA methylation of the paternal genome in 2-cell mouse embryos
Authors: X.S. Ma1, X.G. Wang1,2, L. Qin1, C.L. Song1, F. Lin1, J.M. Song1, C.C. Zhu1 and H.L. Liu
The developmental dynamics of DNA methylation events have been well studied. Active demethylation of the paternal genome occurs in the zygote, passive demethylation occurs during cleavage stages, and de novo methylation occurs by the blastocyst stage. It is believed that the paternal genome has lower levels of methylation during early development than the.. Read More»
- Genet. Mol. Res. 13(4):
DNA elimination in embryogenic development of Pennisetum glaucum x Pennisetum purpureum (Poaceae) hybrids
Authors: J.D. Nunes1, A.L.S. Azevedo1, A.V. Pereira1, C.M.P. Paula2, J.M.S. Campos3, F.J.S. L�?©do1 and V.B. Santos4
Interspecific hybridization between Napier grass (Pennisetum purpureum), which is widely grown in Brazil for cattle forage, and pearl millet (Pennisetum glaucum) has been used as a breeding strategy for the development of improved cultivars. However, the hybrid between these two species is sterile due to its triploid condition (2n = 3x = 21 chromosomes), .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.22.1
- DOI:
- 10.4238/2013.October.22.1
Interleukin-7 receptor gene polymorphism at +1237 locus and its effect on susceptibility to opportunistic infections among HIV and AIDS patients in Limpopo Province, South Africa
Authors: A. Samie, G.T. Moloro and T.C. Nangammbi
Over the past decade, an increasing number of studies have demonstrated correlations between host genetics and susceptibility to diseases. However, few studies have investigated the effects of host genetics on the occurrence of opportunistic infections among human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients. In the .. Read More»
- Genet. Mol. Res. 13(4):