Human Genetics
Fourier-Transform Infrared Spectroscopy, Antioxidant, Phytochemical and Antibacterial Screening of N-Hexane Extracts of Punica granatum, A Medicinal Plant
Authors: M. Sharif, F. Ansari, A. Malik, Q. Ali, Z. Hasan and N.U.H. Khan
Pomegranate is a fruit bearing plant belonging to Lythraceae; in botanic language it is called Punica granatum. It is been considered as a traditional medicine for the cure of many diseases. The purpose of this study was to investigate the antimicrobial activity and phytochemicals present qualitatively present in different parts of Pomegranate plant and t.. Read More»
- Genet. Mol. Res. 19(4):
Targeted Delivery of Insulin by Psyllium Plant (Plantago ispaghula) based hydrogels/membranes
Authors: A.J. Sami, U. Ahmad, M. Karamat, M.N. Hafeez and Q. Ali
Developments in therapeutics are the need of hour for the benefit of mankind and to increase the quality of life. Diabetes mellitus is a non-curable disease affecting a great amount of world’s population. This genetic disorder gets worse with time and ultimately leads to various complications like renal failure, lower limb amputation, heart diseases.. Read More»
- Genet. Mol. Res. 19(2):
Editorial Highlights for Journal of Genetics and Molecular Research
Authors: H. Sasi
I am pleased to mention that during the year 2019, all issues of volume 18 were published online well within the time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. Genetics and Molecular Research (GMR) successfully released issues with 70 abstracts. The submissions to the journal are subjected to .. Read More»
- Genet. Mol. Res. 19(2):
Genetics and Molecular Research: Editor Note
Authors: M. Akram
We are pleased to bring you the third issue of 2020. Along with few original papers and review papers, for this issue we decided to acknowledge the contributions during this COVID-19 crisis. We would like to appreciate your interest and supports towards the Genetics and Molecular Research. We understand the tough times that everyone is facing during this .. Read More»
- Genet. Mol. Res. 19(4):
Evaluation of Genetic Variability in Wheat and Maize under Heavy Metal and Drought Stress
Authors: M. Tahir, M.S. Rashid, Q. Ali and A. Malik
There are certain conditions which cause a change in the growth pattern of plants. These circumstances are significantly effective in growth and cultivation of major crops. The effects of higher levels of copper sulphate through fertilizers can be effective in reducing the growth of a healthy plant. An experiment was conducted in the greenhouse of Institu.. Read More»
- Genet. Mol. Res. 19(3):
Hepatitis B and C prevalence and its associated risk factors among school going children in urban and rural areas of District Muzaffar Garh, Pakistan
Authors: Sikandar Hayat, Muhammad Naeem, Arif Malik, Qurban Ali, Muhammad Khalid, Samrah Masud and Arif Mahmood Bhutta
Viral Hepatitis like hepatitis B and hepatitis C are the serious cause of mortality in Pakistan. Present study estimated the prevalence and risk factors associated with Hepatitis B and C among school going children from urban and rural areas. In urban areas overall prevalence of HBV was 5% where the highest prevalence of HBV was 80% and 20% in males and f.. Read More»
- Genet. Mol. Res. 19(1):
Asp299Gly polymorphism in TLR4 gene in patients with colorectal cancer
Authors: S. M. Shoeib, W. S. Mohamed, H. M. Nagy
Background: Toll-like receptors play important roles in innate and adaptive immunity and polymorphisms within TLR-4 as Asp299Gly are reported to be associated with certain digestive cancers e.g. colorectal carcinoma. Aim: Investigate the association between Asp299Gly polymorphism and the risk of colorectal cancer .. Read More»
- Genet. Mol. Res. 18(1):
Electroporation induced membrane permeability changes at the ionic level
Authors: Sadasivam Pachamuthu, Zubin A Zaheer, Bhuvaneshwari Sampath, Dharani Muralidharan, Rajaprabu Ramachandran and Kavitha Sankaranarayanan
Background/Aim: Electrochemotherapy is an innovative method for the localized treatment of cutaneous and subcutaneous metastatic cancers. The aim of the study is to assess the changes at the plasma membrane and its recovery time by monitoring the regulated passage of ions through specific ion channels as measured by electrophysiology. Materials an.. Read More»
- Genet. Mol. Res. 18(3):
Synonymous Variant of ACE Gene (rs4343) is Coupled with Early Age at Onset and Diminished Diabetic Duration in South Indian Diabetic Nephropathy Patients
Authors: S. Babi Heera, Umme Najiya Mahwish, Fazul Rahman, Sayeeduddin S, Sree Bhushan Raju , Parveen Jahan
Diabetic nephropathy (T2DN) is a major micro vascular complication associated with type-2 diabetes (T2DM). Abnormally active Renin Angiotensin System pathway is shown to influence the development of T2DN and the inter-individual variation with respect to ACE levels, a key enzyme in this pathway partly dependent on the genetic variants of ACE.. Read More»
- Genet. Mol. Res. 19(5):
Integrative omics of ovarian cancer
Authors: Yanisa Rattanapan and Takol Chareonsirisuthigul
Omics such as genomics, transcriptomics, proteomics, and metabolomics are gathering the study of entire characterization and molecular biology processes of organisms. The advancement in studying omics has become useful and widely applied to many human diseases. For ovarian cancer, pathogenic mechanisms at molecular levels resulting in the development of c.. Read More»
- Genet. Mol. Res. 18(4):