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Human Genetics   Research Article

CD40 rs4810485 T>G polymorphism and susceptibility to ankylosing spondylitis in the Latvian population

Authors: J. Zepa, L. Silamiķele, I. Bulina, V. Lavrentjevs, I. Trapina, J. Klovins, D. Andersone, A. Lejnieks and L. Nikitina-Zake

Ankylosing spondylitis (AS) is a potentially disabling form of a systemic chronic inflammatory arthritis affecting mainly the axial skeleton, with or without extraspinal manifestations. The genetic basis of AS is partly known. Moreover, many autoimmunityrelated genes have pleiotropic effects. Multiple functional polymorphisms .. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18081
DOI:
http://dx.doi.org/10.4238/gmr18081
Human Genetics   Research Article

Genetic structure and diversity of Senefeldera verticillata (Euphorbiaceae) in semideciduous seasonal forest fragments

Authors: A.A.R. Vieira, A.L. Silva Júnior, L.C. Souza, F.D. Miranda, M.F.S. Ferreira and M.V.W. Caldeira

Senefeldera verticillata (Euphorbiaceae) is a species that exclusively occurs in the Atlantic Forest; it is used in the restoration and recovery of degraded areas and has therapeutic uses. Due to the scarcity of information on genetic patterns of this species, genetic diversity was characterized by the use of molecular markers.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18059
DOI:
http://dx.doi.org/10.4238/gmr18059
Human Genetics   Research Article

Effect of the PLAG1 gene polymorphism on oleic acid percentage in Japanese Black cattle populations

Authors: H. Kigoshi, F. Kawaguchi, R. Yasuzumi, K. Oyama, H. Mannen, S. Sasazaki

We investigated the effect of the PLAG1 gene (on bovine chromosome 14) polymorphism on oleic acid percentage (C18:1) in four Japanese Black cattle populations (JB1: n = 900, JB2: n = 560, JB3: n = 456, JB4: n = 450). We genotyped the PLAG1 polymorphism (rs109231213) for four populations and then analyzed the effects on carcass.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18056
DOI:
http://dx.doi.org/10.4238/gmr18056
Human Genetics   Research Article

Infertility caused by an association between Arg72Pro polymorphism of the p53 gene and Glu298Asp of the eNOS gene in patients with endometriosis

Authors: T.R. Santos, K.S.F. e Silva, R.C.P.C. Silva, K.K.V.O. Moura, L.A. Guillo, C.L. Ribeiro Júnior and I.R. Costa

Endometriosis is characterized by ectopic endometrial tissue and affects millions of women worldwide. The disease leads to various symptoms such as chronic pelvic pain and infertility and does not yet have a well-defined etiology. The pathology is similar to cancer, since endometrial cells are highly proliferative, invade tiss.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18046
DOI:
http://dx.doi.org/10.4238/gmr18046
Human Genetics   Research Article

High precision experimental statistics for the selection of common bean lines that have superior agronomic performance

Authors: N.D. Ribeiro, S. de M. Steckling and H.C. Mezzomo

The identification of a single statistic that allows selection of superior genotypes for several agronomic traits with high experimental precision would be useful for bean breeding programs. We examined correlations between 12 statistics for agronomic traits to determine which would be useful for the selection of common bean l.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18042
DOI:
http://dx.doi.org/10.4238/gmr18042
Human Genetics   Research Article

Detection of sequences related to biosynthesis of antifungal metabolites and identification of a PhzF-like gene in a Pseudomonas rhizobacterium of Piper tuberculatum

Authors: O.S. Silva Jr., N.L.F. Barros, A.S. Siqueira, E.C. Gonçalves, D. N. Marques, S.P. Reis, and C.R.B. Souza

Our previous studies identified a Pseudomonas putida (Pt12 isolate) associated with roots of Piper tuberculatum Jacq., a Piperaceae occurring in the Amazon region with known resistance to infection by Fusarium solani f. sp. piperis, the causal agent of root rot disease in black pepper (Piper nigrum L.). This Pt12 isolate was a.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18035
DOI:
http://dx.doi.org/10.4238/gmr18035
Human Genetics   Research Article

One-Step RT-qPCR assay for detection and quantification of equine infectious anemia virus in-vitro

Authors: B.L. Bueno, F.G. Oliveira, G.K. Lima1, A.A. Fonseca Júnior, T.C. Kassar, R.J.F. Câmara, R.C. Leite and J.K.P. Reis

Equine infectious anemia virus (EIAV) infection often results in an initial febrile response, followed by recurrent cycles of the disease and finally, a prolonged asymptomatic period. These variations in clinical signs are due to a number of factors, including virus strain, equid species and differences in susceptibility among.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18027
DOI:
http://dx.doi.org/10.4238/gmr18027
Human Genetics   Research Article

Phenotypic and predicted genetic approaches for genotype ranking of wheat seed yield in Brazil

Authors: V.J. Szareski, I.R. Carvalho, K. Kehl, A.M. Levien, T.C. da Rosa, M.H. Barbosa, G.H. Demari, J.R. Pimentel, C. Troyjack, V.Q. de Souza, E.G. Martinazzo,F.A. Villela, T. Pedó and T.Z. Aumonde

This work was aimed at determining stability and adaptability through Additive Main Effects and Multiplicative Interaction (AMMI) and Genotype Main Effects and Genotype Environment Interaction (GGE) methodologies, as well as to estimate and predict Restricted Maximum Likelihood/Best Linear Unbiased Prediction (REML/BLUP) param.. Read More»

Genet. Mol. Res. 17(3):
http://dx.doi.org/gmr18026
DOI:
http://dx.doi.org/10.4238/gmr18026
Human Genetics   Research Article

Null polymorphisms in GSTT1 and GSTM1 genes and their associations with smoking and cervical cancer

Authors: Ana Lúcia Munaro Tacca, Ana Karolina Lopes, Cesar Augusto Sam Tiago Vilanova-Costa, Antonio Marcio Teodoro Cordeiro Silva, Sergio Henrique Nascente Costa, Nathalia Amaral Nogueira, Jessica Enocencio Porto Ramos, Andrea Alves Ribeiro, Vera Aparecida Saddi

Human Papillomavirus (HPV) infection is the main risk factor for cervical cancer. However, other risk factors include smoking and genetic susceptibility. Glutathione-S-Transferases (GST) is enzymes involved in tobacco carcinogens metabolism and genes encoding these enzymes are highly polymorphic. The objective of this study wa.. Read More»

Genet. Mol. Res. 17(2):
http://dx.doi.org/gmr16039918
DOI:
http://dx.doi.org/10.4238/gmr16039918
Human Genetics   Research Article

Interleukin-27−924A/G gene polymorphism is associated with Rheumatoid Arthritis in Egyptian population

Authors: A. Badawy, A.H. Mohamed, A.A. Enein, R. Qasem, E. Rizk, E. El-Masry , S. Abdellatif and M. Balata

Rheumatoid arthritis (RA) is an autoimmune disease with increasing activity of T lymphocytes and abnormal production of inflammatory cytokines. Interleukin-27 (IL-27), a multifunction cytokine with contradictory inflammatory effect. Polymorphism of IL-27 was reported to be predisposed to many inflammatory diseases and autoimmu.. Read More»

Genet. Mol. Res. 17(2):
gmr16039915
DOI:
10.4238/gmr16039915

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