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Human Genetics

Human Genetics   Research Article

The influence of brood comb cell size on the reproductive behavior of the ectoparasitic mite Varroa destructor in Africanized honey bee colonies

Authors: Giancarlo A. Piccirillo, D. De Jong

Africanized honey bees (Apis mellifera, Hymenoptera: Apidae) in Brazil are tolerant of infestations with the exotic ectoparasitic mite, Varroa destructor (Mesostigmata: Varroidae), while the European honey bees used in apiculture throughout most of the world are severely affected. Africanized honey bees are normally kept in hi.. Read More»

Genet. Mol. Res. 2(1):
Human Genetics   Research Article

Association between diabetes type 1 and DQB1* alleles in a case-control study conducted in Montevideo, Uruguay

Authors: Adriana Mimbacas, Francisco P�©rez-Bravo, Pedro C. Hidalgo, Gerardo Javiel, Carmen Pisciottano, Rosario Grignola, Ana Mar�­a Jorge, Juan Pablo Gallino, Jackeline Gasagoite, Horacio Cardoso

We studied HLA DQB1 allele frequencies and the relative risk (RR) of various genotypes in 72 type 1 diabetic patients and 40 control individuals in Uruguay. This is a tri-racial (Caucasian, Black and Indo-American) mixed population. The products of the polymerase chain reaction amplifications were hybridized with oligonucleoti.. Read More»

Genet. Mol. Res. 2(1):
Human Genetics   Research Article

Cell biology, molecular embryology, Lamarckian and Darwinian selection as evolvability

Authors: H. Hoenigsberg

The evolvability of vertebrate systems involves various mechanisms that eventually generate cooperative and nonlethal functional variation on which Darwinian selection can operate. It is a truism that to get vertebrate animals to develop a coherent machine they first had to inherit the right multicellular ontogeny. The ontogen.. Read More»

Genet. Mol. Res. 2(1):
Human Genetics   Research Article

No evidence for minority male mating advantage in wild type strains of Drosophila ananassae tested in multiple-choice experiments

Authors: Arundhati Som and Bashisth N. Singh

Minority male mating advantage was tested in wild type strains of Drosophila ananassae through multiple-choice experiments. Mating success of two types of flies present in five different ratios was scored by direct observation in an Elens-Wattiaux mating chamber. We found no evidence for minority male mating advantage in wild .. Read More»

Genet. Mol. Res. 1(4):
Human Genetics   Research Article

Ectodermal dysplasias (group A): elaborationof a computerized database to help withgenetic-clinical diagnosis(Displasias ectod�©rmicas do grupo A:elabora�§�£o de um banco de dadosinformatizado para aux�­lio ao diagn�³sticogen�©tico-cl�­nico)

Authors: Toni Lisboa Costa

Ectodermal dysplasias are conditions that involve structures derived from the ectoderm, such as the epidermis and its enclosures, constituting a large and complex nosologic group, composed of rare entities with genetic etiology (in their majority). Freire-Maia, in 1971 and 1977, proposed a clinical definition and a clinical-mn.. Read More»

Genet. Mol. Res. 1(3):
Human Genetics   Research Article

Molecular detection of XO - Turner syndrome

Authors: Carlos Alberto Longui, Mylene Neves Rocha,Liana Carla Albuquerque Peres Martinho,Gustavo Gir Gomes, Ricardo Eustachio de Miranda,Thomas Alves de Souza Lima, M�´nica Barbosa Melo and Osmar Monte

Turner syndrome is caused by haploinsufficiency of the short arm of X-chromosome, and is usually diagnosed by karyotyping. This procedure is time-consuming, expensive and unfeasible for population screening. We propose molecular detection of 45XO Turner patients based on the ability of HpaII, a methylation sensitive endonuclea.. Read More»

Genet. Mol. Res. 1(3):
Human Genetics   Research Article

Frequencies of GSTM1, GSTT1, and GSTP1 polymorphisms in a Brazilian population

Authors: Ana Rossini, Davy C.M. Rapozo, L�­dia M.F. Amorim, Jacyara M.B. Macedo1, Raquel Medina, Jos�© F.N. Neto, Cl�¡udia V.M. Gallo and Luis F.R. Pinto

The glutathione S-transferase (GST) family of enzymes has a vital role in phase II of biotransformation of environmental carcinogens, pollutants, drugs and other xenobiotics. GSTs are polymorphic, with the type and frequency of polymorphism being ethnic dependent. Polymorphisms in GST genes have been shown to be associated wit.. Read More»

Genet. Mol. Res. 1(3):
Human Genetics   Research Article

Transferrin polymorphism in Central Amazon populations of pescada, Plagioscion squamosissimus

Authors: Aylton Saturnino Teixeira, Alan Jamieson and Jos�© Carlos Paula Raposo

lood plasma of 253 specimens from eight population samples of the sciaenid fish, pescada (Plagioscion squamosissimus), caught from four sites in the Central Amazon, was tested for molecular variants of transferrin. Starch gel electrophoresis was used to distinguish six species of transferrin molecules; 12 of the 21 theoretical.. Read More»

Genet. Mol. Res. 1(3):
Human Genetics   Book Review

A Student Handbook for Writing in Biology

Authors: Karin Knisely

 -.. Read More»

Genet. Mol. Res. 1(2):