Table of Contents | Genet. Mol. Res.2016(1)
Matrix metalloproteinase 9 -1562C/T polymorphism increased protein levels in patients with colorectal cancer in a sample from southeastern Brazil
Authors: C.R. Hoelzle, K.C.S.F. Magalh�£es, S.S. Carvalho, G.A. Santos, I.M. Maia, M.C.P.S. Sousa, J.S. Andrade-Filho, G.M.G. Cruz and R.T. Sim�µes
We examined whether the allelic and/or genotypic profile of locus -1562C/T of the matrix metalloproteinase (MMP-9) gene influences the protein expression levels of MMP-9 in patients with colorectal cancer (CRC) compared with controls. A total of 104 patients with CRC and 84 controls were evaluated. Peripheral blood was collected from both groups and DNA e.. Read More»
Genet. Mol. Res. 15(1): gmr.15017478
DOI: 10.4238/gmr.15017478
Association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population
Authors: R.J. Li, M. Li, G.J. Liu, Y.W. Guo, H. Bai, P. Xiao and J.Z. Mei
We conducted a hospital-based case-control study to investigate the association between 3 common SNPs in the ERCC5 gene (rs1047768, rs751402, and rs17655) and the risk of developing gastric cancer. Between January 2013 and December 2014, samples were collected from 216 gastric cancer patients and 216 control subjects. ERCC5 rs1047768, rs751402, and rs1765.. Read More»
Genet. Mol. Res. 15(1): gmr.15017510
DOI: 10.4238/gmr.15017510
Association of the interleukin-10 gene -1082A/G genetic polymorphism with risk of ischemic stroke in a Chinese population
Authors: W.Z. Li, C.Y. Gao, W.L. He and H.M. Zhang
We investigated the possible association between two single nucleotide polymorphisms of IL10 (-1082A/G and -592C/A) and susceptibility to ischemic stroke. In total, 335 patients with proven ischemic stroke and 335 control subjects were recruited from Xinxiang Central Hospital between March 2013 and May 2015. The IL10 -1082A/G and -529C/A polymorphisms wer.. Read More»
Genet. Mol. Res. 15(1): gmr.15017541
DOI: 10.4238/gmr.15017541
Association of LRP5 Ala1330Val polymorphism with fracture risk: a meta-analysis
Authors: J. Peng, Y. Lu, Y.J. Liu and Y.L. Zhan
Numerous studies have evaluated the association between the Ala1330Val polymorphism of the low-density lipoprotein receptor-related proteins 5 (LRP5) gene and fracture risk. However, the specific association is still controversial. The aim of this study was to investigate their correlation via meta-analysis. and EMBASE databases were searched, and data we.. Read More»
Genet. Mol. Res. 15(1): gmr.15017552
DOI: 10.4238/gmr.15017552
Genomic ancestry evaluated by ancestry-informative markers in patients with sickle cell disease
Authors: A.F. Nascimento, J.S. Oliveira2, J.C. Silva Junior and A.A.L. Barbosa
The bs mutation is responsible for the most aggressive form of sickle cell disease, has a predominantly African origin, and arrived in Brazil through the slave trade. However, the Brazilian population is highly miscegenated, underscoring the importance of ancestry-informative markers (AIMs) for the identification of the geneti.. Read More»
Genet. Mol. Res. 15(1): gmr.15017604
DOI: 10.4238/gmr.15017604
Large-scale tissue-specific and temporal gene expression profiles in Pengze crucian carp
Authors: Y. Zheng, J.Z. Chen, H.P. Wang, M. Li, H.W. Liang, X.W. Bing and Z.Z. Wang
In the present study, the tissue-specific and temporal gene expression profiles of four catalogues of gonadal development-related genes (sex differentiation-related, steroid receptor, steroidogenic, and structural genes) were detected in nine tissues and during 11 successive developmental stages in the Pengze crucian carp (Pcc.. Read More»
Genet. Mol. Res. 15(1): gmr.15017642
DOI: 10.4238/gmr.15017642
Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus samples obtained from farms in Gansu, China
Authors: M.Z. Huang, H. Wang S.Y. Wang, D.A. Cui, X. Tuo and Y.M. Liu
Porcine epidemic diarrhea poses significant sanitation problems in the porcine industry, and has negatively affected the economy in recent years. In this study, 48 fecal specimens were collected from piglets from four intensive swine farms located in the Gansu Province of China. The molecular diversity and phylogenetic relatio.. Read More»
Genet. Mol. Res. 15(1): gmr.15017696
DOI: 10.4238/gmr.15017696
Phenotypic characteristics for discrimination between advanced genotypes of Brachiaria ruziziensis
Authors: B.A. Rezende, C.B. Ribeiro, D.H.L. Teixeira, F.M.A. Gon�§alves and F. Souza Sobrinho
The aim of this study was to use multivariate methods and Pearson and partial correlations to disregard phenotypic characteristics that contribute little to differentiation between Brachiaria ruziziensis genotypes. Eighty-one genotypes of B. ruziziensis were assessed in completely randomized blocks with three replications. Ten phenotypic characteristics w.. Read More»
Genet. Mol. Res. 15(1): gmr.15017774
DOI: 10.4238/gmr.15017774