
Authors: R. Hill, A. Canal, K. Bondioli, R. Morell and M.D. Garcia
The objective of the present study was to investigate single nucleotide polymorphisms (SNPs) located in three candidate genes previously reported to have effects on fertility and milk production traits in a population of 123 Holstein cows. The milk production traits evaluated included lifetime averages of milk yield, protein c.. Read More»
Genet. Mol. Res. 15(1): gmr.15017794
DOI: 10.4238/gmr.15017794
Authors: E. De Fran�§a, D.S.B.S. Silva, T.F.C. Silva, C.L. Dornelles, J.G. Alves and C.S. Alho
Single nucleotide polymorphisms in the APOA5 gene have been studied for their association with metabolic syndrome. Thus, elucidating the effect of the mechanism involved in APOA5 gene polymorphisms on lipid metabolism is of great importance. In this study we aimed to determine the allelic and genotypic frequencies of -1131T>C, Ser19Trp, and intergenic .. Read More»
Genet. Mol. Res. 15(1): gmr.15017809
DOI: 10.4238/gmr.15017809
Authors: V.M. Oliveira, O.T. Hamawaki, A.O. Nogueira, L.B. Sousa, F.M. Santos and R.L. Hamawaki
Advances in genetic enhancement techniques have led to an increase in soybean production. Thus, soybean is currently one the most economically important cultured species worldwide. The objectives of the present study were to study the interaction of soybean genotypes per environment in terms of grain productivity and to evaluate their phenotypic adaptabil.. Read More»
Genet. Mol. Res. 15(1): gmr.15017843
DOI: 10.4238/gmr.15017843
Authors: M.G. He, K. Zheng, D. Tan and Z.X. Wang
We conducted a study to investigate the association between ERCC1 (rs3212986) and ERCC2 (rs13181) gene polymorphisms and the risk of pancreatic cancer in a Chinese population. A total of 217 pancreatic cancer patients and 244 control subjects were recruited from the Nuclear Industry 215 Hospital of Shaanxi Province between February 2013 and December 2014... Read More»
Genet. Mol. Res. 15(1): gmr.15017879
DOI: 10.4238/gmr.15017879
Authors: D.C. Casagrande, J.C.L. Ribalta, K.D.P.F. Leite, M. Schimidt and N.M.D.G. Speck
We verified the prevalence of human papillomavirus (HPV) E6/E7 protein mRNA expression in patients with low-grade squamous intraepithelial lesions (LSILs) and negative cervicovaginal cytology. To investigate the relationship between mRNA expression and viral infection type, we assessed genotyping in single infections. Samples from 825 women were submitted.. Read More»
Genet. Mol. Res. 15(1): gmr.15017916
DOI: 10.4238/gmr.15017916
Authors: X.H. Fu, W.Q. Zhang and X.S. Qu
We performed an exploratory study by analyzing the correlation of 46, XY disorders of sex development (46, XY DSD) with androgen receptor (AR) and steroid 5α-reductase-2 (SRD5A2) gene mutations and a safety analysis of dihydrotestosterone (DHT) gel treatment for pediatric micropenis. We collected samples from 76 pediatric patients with 46, XY DSD an.. Read More»
Genet. Mol. Res. 15(1): gmr.15018232
DOI: 10.4238/gmr.15018232