Table of Contents | Genet. Mol. Res.2016(1)
Correlation between the 677C>T polymorphism in the methylene tetrahydrofolate reductase gene and serum homocysteine levels in coronary heart disease
Authors: Y.Y. Chen, B.N. Wang and X.P. Yu
The aim of the current study was to explore the correlation between serum homocysteine (HCY) levels and the methylene tetrahydrofolate reductase (MTHFR) gene 677C/T polymorphism and coronary heart disease (CHD). We consecutively enrolled 208 patients with CHD confirmed by CTA or coronary angiography from our hospital. An addit.. Read More»
Genet. Mol. Res. 15(1): gmr.15017238
DOI: 10.4238/gmr.15017238
Pivotal role of microRNA-9 in osteosarcoma tumorigenesis and tumor progression
Authors: X.J. Qi, J.F. Wang, G.D. Wang, Q. Xu and H.L. Sun
MicroRNA-9 (miR-9) has a well-established role in various tumors; the clinical significance and potential mechanism of miR-9 in human osteosarcoma (OS) has not been elucidated. The aim of this study was to investigate the mechanism and role of miR-9 expression in osteosarcoma cells. miR-9 expression in the OS cell line MG-63 and OS tissues was compared to.. Read More»
Genet. Mol. Res. 15(1): gmr.15017318
DOI: 10.4238/gmr.15017318
A new method for estimating the number of non-differentially expressed genes
Authors: J. Wu, C.Y. Liu, W.T. Chen, W.Y. Ma and Y. Ding
Control of the false discovery rate is a statistical method that is widely used when identifying differentially expressed genes in high-throughput sequencing assays. It is often calculated using an adaptive linear step-up procedure in which the number of non-differentially expressed genes should be estimated accurately. In this paper, we discuss the estim.. Read More»
Genet. Mol. Res. 15(1): gmr.15017402
DOI: 10.4238/gmr.15017402
Nucleolar-persistence phenomenon during spermatogenesis in genus Meccus (Hemiptera, Triatominae)
Authors: F.F. Madeira, A.A.C. Lima, J.A. Rosa, M.T.V. Azeredo-Oliveira and K.C.C. Alevi
The Triatominae subfamily consists of 150 species in 18 genera, grouped into six tribes. In cytogenetics, triatomines are important biological models because they have holocentric chromosomes and nucleolar persistence in meiosis. The phenomenon of nucleolar persistence has been described for 23 species of triatomine in three g.. Read More»
Genet. Mol. Res. 15(1): gmr.15017427
DOI: 10.4238/gmr.15017427
Chemical signatures in the developmental stages of Protopolybia exigua
Authors: E.R.S. Silva, K.B. Michelutti, W.F. Antonialli-Junior, M. Batistote and C.A.L. Cardoso
The chemical signature of social insects is very important for communication, and specific signs of each colony and its individuals are acquired throughout their development. This chemical signature can also be related to the composition of the materials employed during nest construction. Furthermore, the venom also contains i.. Read More»
Genet. Mol. Res. 15(1): gmr.15017586
DOI: 10.4238/gmr.15017586
Evaluation of the efficiency of artificial neural networks for genetic value prediction
Authors: G.N. Silva, R.S. Tomaz, I.C. Sant�Anna, V.Q. Carneiro, C.D. Cruz and M. Nascimento
Artificial neural networks have shown great potential when applied to breeding programs. In this study, we propose the use of artificial neural networks as a viable alternative to conventional prediction methods. We conduct a thorough evaluation of the efficiency of these networks with respect to the prediction of breeding values. Therefore, we considered.. Read More»
Genet. Mol. Res. 15(1): gmr.15017676
DOI: 10.4238/gmr.15017676
MicroRNA analysis in model species based on evolutionary rates
Authors: X.F. Mao and Y.C. Cao
MicroRNAs (miRNAs) are major post-transcriptional regulators of gene expression. In an attempt to gain insights into miRNAs at the macroevolutionary level, we performed a systematic analysis of miRNAs in six model organisms based on their evolutionary rates. First, we calculated their miRNA evolutionary rates, and found that they did not correlate with th.. Read More»
Genet. Mol. Res. 15(1): gmr.15017216
DOI: 10.4238/gmr.15017216
STAT1 inhibitor alleviates spinal cord injury by decreasing apoptosis
Authors: Y.X. Wu, C.Z. Gao, K.L. Fan, L.M. Yang and X.F. Mei
Spinal cord injury (SCI) is typically caused by trauma or disease, and it severely affects patients’ motor function. The relationship between signal transducers and activators of transcription-1 (STAT1) and neuronal death after cerebral focal ischemia has been comprehensively studied, but its role in SCI remains largely .. Read More»
Genet. Mol. Res. 15(1): gmr.15017271
DOI: 10.4238/gmr.15017271