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Human Genetics   Research Article
Genetic background of Escherichia coli isolates from peritoneal dialysis patients with peritonitis and uninfected control subjects

Authors: Y.F. Li1,, N. Su, S.Y. Chen, W.X. Hu, F.F. Li, Z.P. Jiang and X.Q. Yu

Escherichia coli is the most common cause of Gram-negative peritonitis resulting in peritoneal function deterioration as well as poor clinical outcome in continuous ambulatory peritoneal dialysis (PD) patients. In this study, we analyzed the phylogenetic background and genetic profile of the E. coli isolates and sought to dete.. Read More»

Genet. Mol. Res. 15(1): gmr.15017341

DOI: 10.4238/gmr.15017341

Medical Genetics   Research Article
Development and characterization of novel microsatellite markers for Ginkgo biloba using 454 pyrosequencing

Authors: Q. Zhou, X.X. Wang, M. Xu, F.L. Cao, F.X. Yu and L.A. Xu

As a “living fossil” that is used to understand the evolutionary history of seed plants, Ginkgo biloba is a well-known multipurpose tree with edible seeds, medicinal properties, and ornamental value, but little is known about its genetic diversity. Microsatellite, or simple sequence repeat (SSR), markers have prove.. Read More»

Genet. Mol. Res. 15(1): gmr.15017385

DOI: 10.4238/gmr.15017385

Plant Genetics   Research Article
Genetic analysis of water-deficit response traits in maize

Authors: M. Ahmad, M. Saleem, M. Ahsan and A. Ahmad

A set of sixty inbred lines of maize (Zea mays L.) were screened in the greenhouse at the seedling stage under both normal and water-deficit conditions. Six water deficit-tolerant inbred lines were selected based on root to shoot ratios. These selected lines were crossed in a diallel pattern. The parental, F1, and reciprocal c.. Read More»

Genet. Mol. Res. 15(1): gmr.15017459

DOI: 10.4238/gmr.15017459

Medical Genetics   Research Article
Association between the MTHFR C677T gene polymorphism and essential hypertension in South West Cameroon

Authors: S.M. Ghogomu, N.E. Ngolle, R.N. Mouliom and B.F. Asa

The association of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and essential hypertension has been reported but with controversial results in diverse populations in Asia and Europe, thereby suggesting a dependency on ethnicity. The aim of this study was to investigate the association between the MTHFR C677T polymorphism and ess.. Read More»

Genet. Mol. Res. 15(1): gmr.15017462

DOI: 10.4238/gmr.15017462

Animal Genetics   Research Article
Analysis of DRB3 gene polymorphisms in Jafarabadi, Mediterranean, and Murrah buffaloes from Brazil

Authors: N.B. Stafuzza, L.M. Olivatto, B.C.M. Naressi, H. Tonhati and M.E.J. Amaral-Trusty

The DRB3 gene is an MHC class II gene that has a high degree of polymorphism with more than 100 alleles described in cattle. This variation contributes to differences among individuals in immune responsiveness and disease resistance. In this study, we searched for allelic variants in exon 2 of the DRB3 gene in 80 river buffaloes of three breeds in Brazil .. Read More»

Genet. Mol. Res. 15(1): gmr.15016368

DOI: 10.4238/gmr.15016368

Human Genetics   Research Article
Effect of procyanidine on VEGFR-2 expression and transduction pathway in rat endothelial progenitor cells under high glucose conditions

Authors: Y. Liu, W.-J. Liao, Z. Zhu, H. Zeng, H.-Q. He, X.-L. Sun, X.-F. Xu, L. Huang, W.-M. Wang, X.-Y. Zhou and Y.-Z. He

The protective effect of procyanidine and its oligomers against high glucose-mediated oxidative stress injury in endothelial progenitor cells (EPCs), and effect of procyanidin on vascular endothelial growth factor receptor-2 (VEGFR-2) expression and downstream signal pathway were analyzed in vitro. Rat bone marrow mononuclear cells were isolated, cultured.. Read More»

Genet. Mol. Res. 15(1): gmr.15016925

DOI: 10.4238/gmr.15016925

Medical Genetics   Research Article
Association between a point mutation at the -743-bp region of the transthyretin (TTR) gene and familial vitreous amyloidosis

Authors: X.M. Nie, S.J. Cai, B. Xie, X.W. Chen and M. Jiang

The aim of this study was to identify changes in the base sequence of the upstream regulatory region of the transthyretin (TTR) gene. Whole-blood DNA was extracted from ten subjects belonging to a family with familial amyloidosis vitreoretinopathy; the upstream regulatory sequence was amplified by polymerase chain reaction, detected by gel electrophoresis.. Read More»

Genet. Mol. Res. 15(1): gmr.15016926

DOI: 10.4238/gmr.15016926

Microbial Genetics   Research Article
Cytogenetic analysis of Triatoma pseudomaculata CorrĂ?ÂȘa and EspĂ?­nola, 1964 (Hemiptera, Triatominae) from different Brazilian states

Authors: C.H.L. Imperador, K.C.C. Alevi, J. Oliveira, J.A. Rosa and M.T.V. Azeredo-Oliveira

Triatoma maculata and T. pseudomaculata are allopatric; however, it is believed that T. maculata was introduced into the Brazilian northeast by passive transportation of the nymphs between the feathers of migratory birds, followed by the speciation of T. pseudomaculata. T. pseudomaculata is the second most epidemiologically important species in the northe.. Read More»

Genet. Mol. Res. 15(1): gmr.15016937

DOI: 10.4238/gmr.15016937