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Animal Genetics   Research Article
Nramp1 gene expression in different tissues of Meishan piglets from newborn to weaning

Authors: C.H. Dai, J.Y. Wu, C.X. Zhao, L.H. Yu, W.B. Bao and S.L. Wu

Natural resistance-associated macrophage protein gene 1 (Nramp1) plays an important role in the innate immune response of swine, and is believed to influence disease resistance. In this study, a real-time quantitative polymerase chain reaction technique was used to investigate Nramp1 expression in 12 different tissues in newbo.. Read More»

Genet. Mol. Res. 16(1): gmr16019288

DOI: 10.4238/gmr16019288

Human Genetics   Research Article
Dynamic relationship between SIPA1 gene and protein expression and the development of gastric cancer

Authors: J.Y. Li, J.B. Wang, C.B. Liu, D.L. Ma, J.H. Ma

Association of signal-induced proliferation-associated 1 (SIPA) gene and protein expression with gastric cancer development was examined. SIPA1 mRNA and protein levels were determined by real-time quantitative polymerase chain reaction and western blot, respectively, in 40 gastric tumor and tumor-adjacent normal tissues. SIPA1.. Read More»

Genet. Mol. Res. 16(1): gmr16019271

DOI: 10.4238/gmr16019271

Plant Genetics   Research Article
Anti-inflammatory effects of essential oils from Mangifera indica

Authors: R.M. Oliveira, T.S. Dutra, E. Simionatto, N. R�©, C.A.L. Kassuya, C.A.L. Cardoso

Mangifera indica is widely found in Brazil, and its leaves are used as an anti-inflammatory agent in folk medicine. The aim of this study is to perform composition analysis of essential oils from the M. indica varieties, espada (EOMIL1) and coração de boi (EOMIL2), and confirm their anti-inflammatory properties. .. Read More»

Genet. Mol. Res. 16(1): gmr16019227

DOI: 10.4238/gmr16019227

Human Genetics   Research Article
Paracrine effect of bone marrow mesenchymal stem cells on proliferation, apoptosis, and alpha-actin-2 expression in hepatic stellate cells

Authors: H.-J. Cao, M.-D. Wang, S.-G. Li, L. Zhu, J.-H. Zheng

We investigated the paracrine effects of bone marrow mesenchymal stem cells (BMSCs) on the proliferation, apoptosis, and alpha-actin-2 (ACTA2) expression of hepatic stellate cells (HSCs), and explored the possible mechanisms of hepatocyte growth factor (HGF). We established a co-culture system by culturing BMSCs on the upper layer and HSCs on the lower la.. Read More»

Genet. Mol. Res. 16(1): gmr16019201

DOI: 10.4238/gmr16019201

Plant Genetics   Research Article
Multivariate diallel analysis allows multiple gains in segregating populations for agronomic traits in Jatropha.

Authors: P.E. Teodoro, E.V. Rodrigues, L.A. Peixoto, L.A. Silva, B.G. Laviola, L.L. Bhering

Jatropha is research target worldwide aimed at large-scale oil production for biodiesel and bio-kerosene. Its production potential is among 1200 and 1500 kg/ha of oil after the 4th year. This study aimed to estimate combining ability of Jatropha genotypes by multivariate diallel analysis to select parents and crosses that allo.. Read More»

Genet. Mol. Res. 16(1): gmr16019545

DOI: 10.4238/gmr16019545

Animal Genetics   Research Article
Mini tomato genotypes resistant to the silverleaf whitefly and to two-spotted spider mites

Authors: G.M. Maciel, R.S. Almeida, J.P.R. da Rocha, V. Andal�³, G.R. Marquez, N.C. Santos and R.R. Finzi

The mini tomato production has expanded, becoming an amazing alternative for enterprise. Despite all commercial potential, the cultivation has the occurrence of pests as main obstacle during the crop development. Nowadays, there are no researches that aimed obtaining genotypes with high acylsugar content, capable of providing .. Read More»

Genet. Mol. Res. 16(1): gmr16019539

DOI: 10.4238/gmr16019539

Plant Genetics   Research Article
Path analysis and canonical correlations for indirect selection of Jatropha genotypes with higher oil yield

Authors: L.A. Silva, L.A. Peixoto, P.E. Teodoro, E.V. Rodrigues, B.G. Laviola, L.L. Bhering

Jatropha is a species with great potential for biodiesel production, and the knowledge on how the main agronomic traits are correlated will contribute to its improvement. Therefore, the objectives of this study were to estimate the genetic parameters of the traits: plant height at 12 and 40 months, canopy projection on the row.. Read More»

Genet. Mol. Res. 16(1): gmr16019562

DOI: 10.4238/gmr16019562

Animal Genetics   Research Article
Immunomodulatory and neuroprotective effect of cryopreserved allogeneic mesenchymal stem cells on spinal cord injury in rats

Authors: I.R. Rosado, P.H. Carvalho, E.G.L. Alves, T.M. Tagushi, J.L. Carvalho, J.F. Silva, M.S.L. Lavor, K.M. Oliveira, R. Serakides, A.M. Goes, E.G. Melo

This study aimed to evaluate the immunomodulatory and neuroprotective effects of allogeneic and cryopreserved mesenchymal stem cells (MSCs) on spinal cord injury. A total of 120 rats were distributed into the following groups: negative control (NC) - without injury, positive control (PC) - with injury without treatment, and group treated with MSC (GMSC) - wi.. Read More»

Genet. Mol. Res. 16(1): gmr16019555

DOI: 10.4238/gmr16019555