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Human Genetics   Research Article
Osteoblast differentiation of rabbit adipose-derived stem cells by polyethylenimine-mediated BMP-2 gene transfection in vitro

Authors: Q.F. Wang, Y. Huang, G.C. He, H.S. Wang, Z.H. Chen, X.H. Cai, Y.H. Xie and Q. Liu

The aim of this study was to examine the efficiency of polyethylenimine-mediated transfection of the human bone morphogenetic protein-2 (BMP-2) gene into rabbit adipose-derived stem cells (ADSCs), and its effect on osteoblast differentiation. Adipose tissue was isolated from the necks of adult Japanese white rabbits and cultur.. Read More»

Genet. Mol. Res. 16(1): gmr16015358

DOI: 10.4238/gmr16015358

Plant Genetics   Research Article
Effects of alendronate on osteoporosis treatment and levels of related cytokines

Authors: C.T. Liu, X.J. Yuan, G.C. Gao

Alendronate regulates the activity of osteoclasts and healing of osteoporosis. This study investigated the effect of alendronate on bone healing and changes in the levels of cytokines. Bilateral ovaries of 10 adult female rabbits were removed surgically in aseptic condition to establish the animal model of osteoporosis. Five rabbits in group A were treate.. Read More»

Genet. Mol. Res. 16(1): gmr16019485

DOI: 10.4238/gmr16019485

Plant Genetics   Research Article
Genetic diversity of mitochondrial control region (D-Loop) polymorphisms in Coilia ectenes taihuensis inhabiting Taihu Lake, China

Authors: J.J. Zhang, J.R. Duan, Y.F. Zhou, J.Y. Peng, D.A. Fang

Coilia ectenes is a commercially important fishery species in China. C. ectenes taihuensis is an endemic and dominant species found in Taihu Lake of China. When compared with C. ectenes, C. ectenes taihuensis lacks anadromous behavior, and can independently grow and reproduce in Taihu Lake. In this study, the mitochondrial DNA.. Read More»

Genet. Mol. Res. 16(1): gmr16019457

DOI: 10.4238/gmr16019457

Plant Genetics   Research Article
Relationship between Psidium species (Myrtaceae) by resistance gene analog markers: focus on nematode resistance

Authors: L.R. Noia, A.C. Tuler, A. Ferreira, M.F.S. Ferreira

Guava (Psidium guajava L.) crop is severely affected by the nematode Meloidogyne enterolobii. Native Psidium species have been reported as sources of resistance against this nematode. Knowledge on the molecular relationship between Psidium species based on plant resistance gene analogs (RGA) can be useful in the genetic breedi.. Read More»

Genet. Mol. Res. 16(1): gmr16019441

DOI: 10.4238/gmr16019441

Human Genetics   Research Article
Association between C807T(C/T) polymorphism of platelet glycoprotein gene and sensitivity to ischemic stroke: a meta-analysis

Authors: C. Luo, L.H. Fan, H. Zhang, J. Zhao, L. Li, L. Zhang, H.X. Zhang and M.M. Ma

Ischemic stroke can lead to loss of neurologic functions. It occurs due to obstruction in blood supply to the brain. It has been proposed that C807T(C/T) polymorphism within the platelet glycoprotein gene may be associated with density and function of glycoprotein Ia/IIa receptors and contributes to the pathogenesis of thrombo.. Read More»

Genet. Mol. Res. 16(1): gmr16019416

DOI: 10.4238/gmr16019416

Animal Genetics   Research Article
Morphology and muscle gene expression in GIFT and Supreme Nile tilapia varieties reared in two cultivation systems

Authors: E.C.S. Lima, J.A. Povh, R.A.A. Otonel, J.H. Leonhardt, A.A. Alfieri, S.A. Headley, F.P. Souza, A.R. Poveda-Parra, P.J. Furlan-Murari, N.M. Lopera-Barrer1

Tissue growth in most fishes occurs by muscular hyperplasia and hypertrophy, which are influenced by different regulatory factors, such as myostatin. The current study evaluated the influence of cultivation in hapas and earthen ponds on the diameter of white muscle fibers and on the myostatin (MSTN-1) gene in GIFT and Supreme .. Read More»

Genet. Mol. Res. 16(1): gmr16019407

DOI: 10.4238/gmr16019407

Plant Genetics   Research Article
Effect of propolis ethanol extract on myostatin gene expression and muscle morphometry of Nile tilapia in net cages

Authors: E.L. Buck, I.Y. Mizubuti, A.A. Alfieri, R.A.A. Otonel, L.Y. Buck,F.P. Souza, O.P. Prado-Calixto, A.R. Poveda-Parra, L. Alexandre Filho, N.M. Lopera-Barrero

Propolis can be used as growth enhancer due to its antimicrobial, antioxidant, and immune-stimulant properties, but its effects on morphometry and muscle gene expression are largely unknown. The present study evaluates the influence of propolis on muscle morphometry and myostatin gene expression in Nile tilapia (Oreochromis ni.. Read More»

Genet. Mol. Res. 16(1): gmr16019404

DOI: 10.4238/gmr16019404

Human Genetics   Research Article
Role of Th1/Th2 cytokines in the diagnosis and prognostic evaluation of ankylosing spondylitis

Authors: J.T. Wen, D.H. Zhang, P.F. Fang, M.H. Li, R.J. Wang, S.H. Li

Ankylosing spondylitis (AS), a progressive disease of the spine, manifests as peripheral arthritis with tendon and ligament inflammation that restricts activity. AS is a rheumatoid autoimmune disease although the rheumatoid factor is absent in patients with AS. It is characterized by inflammatory changes such as elevated level.. Read More»

Genet. Mol. Res. 16(1): Ankylosing spondylitis; Th1; Th2; Inflammatory cytokines

DOI: Ankylosing spondylitis; Th1; Th2; Inflammatory cytokines