Table of Contents | Genet. Mol. Res.2017(1)
Effects of ginsenoside Rg1 on glucose metabolism and liver injury in streptozotocin-induced type 2 diabetic rats
Authors: W. Tian, L. Chen, L. Zhang, B. Wang, X.B. Li, K.R. Fan, C.H. Ai, X. Xia, S.D. Li, Y. Li
Type 2 diabetes mellitus (T2-DM) is a chronic metabolic disorder characterized by high blood glucose levels. T2-DM patients suffer from many complications, such as diabetic fatty liver and diabetic nephropathy. The liver, the pivotal organ involved in both glucose and lipid metabolism, is primarily damaged in T2-DM patients, e.. Read More»
Genet. Mol. Res. 16(1): gmr16019463
DOI: 10.4238/gmr16019463
Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases
Authors: Z.-Z. Liang, J. Li, S.-G. Huang
The objective of this study was to observe the distribution of macrophages (MPs) expressing transforming growth factor beta-1 (TGF-β1) in tissue samples from patients with different human chronic periapical diseases. In this study, samples were collected from 75 volunteers, who were divided into three groups according to .. Read More»
Genet. Mol. Res. 16(1): gmr16019329
DOI: 10.4238/gmr16019329
Effect of overexpression of citrus 9-cis-epoxycarotenoid dioxygenase 3 (CsNCED3) on the physiological response to drought stress in transgenic tobacco
Authors: A.M. Pedrosa, L.C. Cidade, C.P.S. Martins, A.F. Macedo, D.M. Neves, F.P. Gomes, E.I.S. Floh, M.G.C. Costa
9-cis-epoxycarotenoid dioxygenase (NCED) encodes a key enzyme in abscisic acid (ABA) biosynthesis. Little is known regarding the regulation of stress response by NCEDs at physiological levels. In the present study, we generated transgenic tobacco overexpressing an NCED3 ortholog from citrus (CsNCED3) and investigated its relev.. Read More»
Genet. Mol. Res. 16(1): gmr16019292
DOI: 10.4238/gmr16019292
Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells
Authors: C. Zhao, Z.G. Ma, S.L. Mou, Y.X. Yang, Y.H. Zhang, W.C. Yao
MiR-200b, a member of the microRNA-200 family, has been identified to be capable of suppressing glioma cell growth through targeting CREB1 or CD133. However, whether miR-200b affects the biological behavior (proliferation, invasion, and migration) of glioma cells is poorly understood. The aim of this study was to evaluate the .. Read More»
Genet. Mol. Res. 16(1): gmr16019281
DOI: 10.4238/gmr16019281
Identification of genes related to floral organ development in pak choi by expression profiling
Authors: H.X. Song, A.M. Ping, M.X. Sun, X.H. Qi, M.Y. Gao, X.Y. Xu,Z.J. Zhu, M.L. Li and L.P. Hou
Pak choi is a highly nutritious vegetable that is widely grown in China, Southeast Asia, and other parts of the world. Because it reproduces by seed, it is very important to understand the mechanism of floral organ development. Therefore, using the Chinese cabbage genome as a reference, this study analyzed the expression profi.. Read More»
Genet. Mol. Res. 16(1): gmr16019233
DOI: 10.4238/gmr16019233
Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population
Authors: F.Z. Si, Y.Q. Feng and M. Han
IL-17 is associated with the occurrence and development of laryngeal cancer. However, no study has reported the association between IL-17 polymorphisms and laryngeal cancer susceptibility. Therefore, we analyzed the association of three polymorphism loci (rs2275913, 197 G/A; rs3748067, 383 A/G; and rs763780, 7488 T/C) of IL-17.. Read More»
Genet. Mol. Res. 16(1): gmr16019076
DOI: 10.4238/gmr16019076