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Plant Genetics   Research Article
Genetic divergence in the common bean (Phaseolus vulgaris L.) in the Cerrado-Pantanal ecotone

Authors: F.A. da Silva, A.M. Corr�ªa, P.E. Teodoro, K.V. Lopes, C.C.G. Corr�ªa

Evaluating genetic diversity among genotypes is important for providing parameters for the identification of superior genotypes, because the choice of parents that form segregating populations is crucial. Our objectives were to i) evaluate agronomic performance; ii) compare clustering methods; iii) ascertain the relative contr.. Read More»

Genet. Mol. Res. 16(1): gmr16019570

DOI: 10.4238/gmr16019570

Animal Genetics   Research Article
Genetic diversity and relatedness between Canind�© and British Alpine goat breeds in Northeastern Brazil accessed by microsatellite markers

Authors: T.S. C�¢mara, J.F. Nunes, F.M. Diniz, G.R. Silva, A.M. Ara�ºjo

The aim of this study was to access the genetic diversity and relatedness between CanindÃ?© and British Alpine goat breeds in the States of PiauÃ?­ and CearÃ?¡ using microsatellite markers. Genomic DNA was isolated from hair samples of 99 goats belonging to six different flocks. A panel of polymorphic heterologous microsatellite loci was used to genotype .. Read More»

Genet. Mol. Res. 16(1): gmr16019569

DOI: 10.4238/gmr16019569

Plant Genetics   Research Article
Multicollinearity in canonical correlation analysis in maize

Authors: B.M. Alves, A. Cargnelutti Filho and C. Burin

The objective of this study was to evaluate the effects of multicollinearity under two methods of canonical correlation analysis (with and without elimination of variables) in maize (Zea mays L.) crop. Seventy-six maize genotypes were evaluated in three experiments, conducted in a randomized block design with three replication.. Read More»

Genet. Mol. Res. 16(1): gmr16019546

DOI: 10.4238/gmr16019546

Plant Genetics   Research Article
Direct effects on scenarios and types of path analyses in corn hybrids

Authors: M. Toebe, A. Cargnelutti Filho, L. Storck and A.D. L�ºcio

The objective of this study was to estimate the direct effects of explanatory variables on the grain yield of corn in the combinations formed by three types of hybrids x two harvests x nine scenarios of explanatory variables x two types of path analyses. Eleven explanatory variables were measured in 361, 373, and 416 single-, .. Read More»

Genet. Mol. Res. 16(1): gmr16019529

DOI: 10.4238/gmr16019529

Plant Genetics   Research Article
Genetic progress in homogeneous regions of wheat cultivation in Rio Grande do Sul State, Brazil

Authors: D.N. Follmann, A. Cargnelutti Filho, A.D. L�ºcio, V.Q. de Souza, M. Caraffa, C.A. Wartha

The State of Rio Grande do Sul (RS) stands out as the largest wheat producer in Brazil. Wheat is the most emphasized winter cereal in RS, attracting public and private investments directed to wheat genetic breeding. The study of genetic progress should be performed routinely at breeding programs to study the behavior of cultiv.. Read More»

Genet. Mol. Res. 16(1): gmr16019517

DOI: 10.4238/gmr16019517

Human Genetics   Research Article
Leptin (rs7799039) and solute carrier family 30 zinc transporter (rs13266634) polymorphisms in Euro-Brazilian pregnant women with gestational diabetes

Authors: A. Teleginski, M. Welter, H.R. Frigeri, R.R. R�©a, E.M. Souza, D. Alberton, F.G.M. Rego, G. Picheth

Leptin (LEP), a protein that plays a fundamental role in the metabolism of energy reserves, and the solute carrier family 30 A8 zinc transporter (SLC30A8) have been consistently associated with diabetes. Women with gestational diabetes are at moderate risk of developing diabetes type 1 and 2 after pregnancy, in addition to com.. Read More»

Genet. Mol. Res. 16(1): gmr16019515

DOI: 10.4238/gmr16019515

Human Genetics   Research Article
Effect of everolimus on the expression of Ki-67 and caspase-3 in patients with neuroendocrine tumors

Authors: H.Y. Zhang, X.B. Cheng, Y. Li, L.D. Jin, H.P. Yin

Tumors, especially neuroendocrine tumors (NETs), can cause adverse effects on human health. The expression and significance of Ki-67 and caspase-3 in NET remain to be further explored. Everolimus is an important drug used for the treatment of NETs. In this study, we aimed to investigate whether everolimus exerts anti-tumor eff.. Read More»

Genet. Mol. Res. 16(1): gmr16019486

DOI: 10.4238/gmr16019486

Human Genetics   Research Article
Association between single nucleotide polymorphisms in AKT1 and the risk of prostate cancer in the Chinese Han population J.

Authors: J.M. Liu, S.H. Cheng, C. Xia, T. Deng, Y.C. Zhu, X. Wei, Z.L. Huang, B.H. Liao, D.Y. Luo, Y.G. Zhang, T. Jin, K.J. Wang, J. Huang, H. Li

AKT1, also known as v-akt murine thymoma viral oncogene homolog 1, is involved in the regulation of cell-survival and anti-apoptotic activities, which may affect the pathogenesis of various cancers. However, the association between genetic variants of AKT1 and the risk of developing prostate cancer has not been investigated be.. Read More»

Genet. Mol. Res. 16(1): gmr16019469

DOI: 10.4238/gmr16019469