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Plant Genetics   Research Article
Path analysis of the energy density of wood in eucalyptus clones

Authors: A.M. Couto, P.E. Teodoro, P.F. Trugilho

Path analysis has been used for establishing selection criteria in genetic breeding programs for several crops. However, it has not been used in eucalyptus breeding programs yet. In the present study, we aimed to identify the wood technology traits that could be used as the criteria for direct and indirect selection of eucalyp.. Read More»

Genet. Mol. Res. 16(1): gmr16019536

DOI: 10.4238/gmr16019536

Plant Genetics   Research Article
Maize endophytic bacteria as mineral phosphate solubilizers

Authors: C.S. de Abreu, J.E.F. Figueiredo, C.A. Oliveira, V.L. dos Santos, E.A. Gomes, V.P. Ribeiro, B.A. Barros, U.G.P. Lana and I.E. Marriel

In the present study, we demonstrated the in vitro activity of endophytic phosphate-solubilizing bacteria (PSB). Fifty-five endophytic PSB that were isolated from sap, leaves, and roots of maize were tested for their ability to solubilize tricalcium phosphate and produce organic acid. Partial sequencing of the 16S rRNA-encodin.. Read More»

Genet. Mol. Res. 16(1): gmr16019294

DOI: 10.4238/gmr16019294

Human Genetics   Research Article
Tumor-suppressive role of Kruppel-like factor 4 (KLF-4) in colorectal cancer

Authors: D.H. Xiu, Y. Chen, L. Liu, H.S. Yang and G.F. Liu

Kruppel-like factors (KLFs) are a group of transcriptional regulators that have recently been identified to exhibit tumor-suppressive function against various gastrointestinal cancers. The present study aims to investigate the expression patterns and prognostic value of KLF-4 in colorectal cancers (CRCs). KLF-4 levels in CRC t.. Read More»

Genet. Mol. Res. 16(1): gmr16019272

DOI: 10.4238/gmr16019272

Medical Genetics   Research Article
Effects of Moquiniastrum polymorphum ssp floccosum ethnolic extract on colorectal carcinogenesis induced by 1,2-dimethylhydrazine

Authors: S.M.A. Limeiras, B.C. Oliveira, L.R. Pessatto, J.R. Pesarini, C.A.L. Kassuya, A.C.D. Monreal, W.B. Cantero, R. Antoniolli-Silva, A.C.M.B. Antoniolli-Silva, M.E.A. Stefanello, R.J. Oliveira

The objective of this study was to evaluate the effect of Moquiniastrum polymorphum ssp floccosum ethanolic extract (MPEE) on 1,2 dimethylhydrazine (DMH)-induced colorectal carcinogenesis in mice. Forty-two male Swiss mice (Mus musculus) were subdivided into six groups (N = 7/group): negative control, DMH, MPEE, pre-treatment,.. Read More»

Genet. Mol. Res. 16(1): gmr16019518

DOI: 10.4238/gmr16019518

Animal Genetics   Research Article
Study on the effects of blueberry treatment on histone acetylation modification of CCl4-induced liver disease in rats

Authors: W. Zhan, X. Liao, T. Tian, L. Yu, X. Liu, B. Li, J. Liu, B. Han, R.J. Xie, Q.H. Ji and Q. Yang

The objective of this study was to investigate the effects of blueberry treatment on histone acetylation modification of carbon tetrachloride (CCl4)-induced liver disease in rats. Laboratory rats were randomly divided into control, hepatic fibrosis, blueberry treatment, blueberry intervention, and natural recovery groups. Rats.. Read More»

Genet. Mol. Res. 16(1): gmr16019188

DOI: 10.4238/gmr16019188

Human Genetics   Research Article
MicroRNA-139 modulates Alzheimer�s-associated pathogenesis in SAMP8 mice by targeting cannabinoid receptor type 2

Authors: Y. Tang, J.S. Bao, J.H. Su and W. Huang

Alzheimer’s disease (AD) is a neurodegenerative disorder, and is the most common type of dementia in the elderly population. Growing evidence indicates that microRNAs (miRNAs) play a crucial role in neuroinflammation associated with AD progression. In this study, we analyzed the expression of microRNA-139 (miR-139) as we.. Read More»

Genet. Mol. Res. 16(1): gmr16019166

DOI: 10.4238/gmr16019166

Human Genetics   Research Article
IL-8 -251A/T polymorphism contributes to coronary artery disease susceptibility in a Chinese population

Authors: R.J. Zhang, X.D. Li, S.W. Zhang, X.H. Li and L. Wu

Interleukin-8 (IL-8) is a mediator of inflammation and plays an important role in regulating immune responses. To date, several studies have tested the association between IL-8 gene polymorphisms and development of coronary artery disease (CAD), but their results have proved to be inconsistent. We conducted an investigation to.. Read More»

Genet. Mol. Res. 16(1): gmr16018224

DOI: 10.4238/gmr16018224

Human Genetics   Research Article
Polymorphism in the third intron of the interferon-�³ gene is associated with susceptibility to multiple sclerosis

Authors: X.L. Wang, F.R. Meng, X. Wang, S.H. Wang and L. Guo

The present study aims to examine the relationship between polymorphisms in the third intron of the IFN-γ gene and their influence on susceptibility to multiple sclerosis. A population-based case-control study was used for this purpose. Multiple sclerosis patients and healthy controls were interviewed. Genetic polymorphi.. Read More»

Genet. Mol. Res. 16(1): gmr16017538

DOI: 10.4238/gmr16017538