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Human Genetics   Research Article
Regularized quantile regression applied to genome-enabled prediction of quantitative traits

Authors: M. Nascimento, F.F. e Silva, M.D.V. de Resende, C.D. Cruz,A.C.C. Nascimento, J.M.S. Viana, C.F. Azevedo, L.M.A. Barroso

Genomic selection (GS) is a variant of marker-assisted selection, in which genetic markers covering the whole genome predict individual genetic merits for breeding. GS increases the accuracy of breeding values (BV) prediction. Although a variety of statistical models have been proposed to estimate BV in GS, few methodologies h.. Read More»

Genet. Mol. Res. 16(1): gmr16019538

DOI: 10.4238/gmr16019538

Plant Genetics   Research Article
Genetic diversity and selection of common bean lines based on technological quality and biofortification

Authors: S. de M. Steckling, N.D. Ribeiro, F.D. Arns, H.C. Mezzomo, M.T.D.F. Possobom

The development of common bean cultivars with high technological quality that are biofortified with minerals, is required to meet the demand for food with health benefits. The objectives of this study were to evaluate whether common bean genotypes differ in terms of technological and mineral biofortification traits, to study t.. Read More»

Genet. Mol. Res. 16(1): gmr16019527

DOI: 10.4238/gmr16019527

Plant Genetics   Research Article
REML/BLUP and sequential path analysis in estimating genotypic values and interrelationships among simple maize grain yield-related traits

Authors: T. Olivoto, M. Nardino, I.R. Carvalho3, D.N. Follmann4, M. Ferrari3, V.J. Szareski5, A.J. de Pelegrin3 and V.Q. de Souza6

Methodologies using restricted maximum likelihood/best linear unbiased prediction (REML/BLUP) in combination with sequential path analysis in maize are still limited in the literature. Therefore, the aims of this study were: i) to use REML/BLUP-based procedures in order to estimate variance components, genetic parameters, and .. Read More»

Genet. Mol. Res. 16(1): gmr16019525

DOI: 10.4238/gmr16019525

Animal Genetics   Research Article
SNP detection using RNA-sequences of candidate genes associated with puberty in cattle

Authors: S.J. Coleman, S.E. Speidel, R.M. Enns, A. Islas-Trejo, J.F. Medrano, S.S. Moore, M.R.S. Fortes, L.T. Nguyen, B. Venus, I.S.D.P. Diaz,F.R.P. Souza, L.F.S. Fonseca, F. Baldi, L.G. Albuquerque, M.G. Thomas, H.N. Oliveira

Fertility traits, such as heifer pregnancy, are economically important in cattle production systems, and are therefore, used in genetic selection programs. The aim of this study was to identify single nucleotide polymorphisms (SNPs) using RNA-sequencing (RNA-Seq) data from ovary, uterus, endometrium, pituitary gland, hypothala.. Read More»

Genet. Mol. Res. 16(1): gmr16019522

DOI: 10.4238/gmr16019522

Human Genetics   Research Article
Association between GSTM1, GSTT1, and GSTP1 polymorphisms and gastric cancer risk, and their interactions with environmental factors

Authors: Z.H. Chen, J.F. Xian and L.P. Luo

Glutathione S-transferase (GST) is an important member of phase II metabolic enzymes; GSTM1, GSTT1, and GSTP1 belong to three subfamilies of the GST enzyme. Polymorphisms in GSTM1, GSTT1, and GSTP1 could affect detoxification processes, and increase individuals’ susceptibility to cancers. We aimed to investigate the asso.. Read More»

Genet. Mol. Res. 16(1): gmr16018877

DOI: 10.4238/gmr16018877

Human Genetics   Research Article
Comparative study of 13 candidate genes applying multi-reference normalization to detect the expression of different fineness in skin tissues of wool sheep

Authors: Y.Z. Tian, T. Usman, K.C. Tian, J. Di, X.X. Huang, X.M. Xu, H. Tulafu, W.W. Wu, X.F. Fu, Y. Bai, M. Tuerxun and A. Maimaiti

Fiber diameter is a useful indicator of wool traits and it is the main determinant of wool quality and value. A comparative study was conducted to analyze the abundance and expression of 13 candidate genes using expression profile microarray analysis and to identify novel molecular markers associated with wool traits to provid.. Read More»

Genet. Mol. Res. 16(1): gmr16018905

DOI: 10.4238/gmr16018905

Plant Genetics   Research Article
Identification and cloning of GOLDEN2-LIKE1 (GLK1), a transcription factor associated with chloroplast development in Brassica napus L.

Authors: Y.L. Pan, Y. Pan, C.M. Qu, C.G. Su, J.H. Li and X.G. Zhang

Photosynthesis is the process by which dry matter accumulates, which affects rapeseed yield. In this study, we identified GOLDEN2-LIKE1 (GLK1), located on chromosome A07 and 59.2 kb away from the single nucleotide polymorphism marker SNP16353A07, which encodes a transcription factor associated with the rate of photosynthesis i.. Read More»

Genet. Mol. Res. 16(1): gmr16018942

DOI: 10.4238/gmr16018942

Animal Genetics   Research Article
Genotypic and allelic frequencies of gene polymorphisms associated with meat tenderness in Nellore beef cattle

Authors: M.E. Carvalho, J.P. Eler, M.N. Bonin, F.M. Rezende, F.H. Biase, F.V. Meirelles, L.C.A. Regitano, L.L. Coutinho, J.C.C. Balieiro and J.B.S. Ferraz

The objectives of this study were to characterize the allelic and genotypic frequencies of polymorphisms in the µ-calpain and calpastatin genes, and to assess their association with meat tenderness and animal growth in Nellore cattle. We evaluated 605 Nellore animals at 24 months of age, on average, at slaughter. The pol.. Read More»

Genet. Mol. Res. 16(1): gmr16018957

DOI: 10.4238/gmr16018957