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Human Genetics   Research Article
An assessment of the correlation between early postinfarction pyramidal tract Wallerian degeneration and nerve function recovery using diffusion tensor imaging

Authors: A.H. Guo, F.L. Hao, L.F. Liu, B.J. Wang and X.F. Jiang

This study aimed to evaluate the clinical significance of diffusion tensor imaging (DTI) in the early diagnosis of pyramidal tract Wallerian degeneration (WD) and assessment of neurological recovery following cerebral infarction. This study included 23 patients with acute cerebral infarction and 10 healthy adult controls. All .. Read More»

Genet. Mol. Res. 16(1): gmr16019035

DOI: 10.4238/gmr16019035

Human Genetics   Research Article
Expression of prion protein in the cerebrospinal fluid of patients with Parkinson�s disease complicated with rapid eye movement sleep behavior disorder

Authors: W.J. Zhang, X.L. Shang, J. Peng, M.H. Zhou and W.J. Sun

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and mainly manifests with decreasing numbers of dopaminergic neurons. Rapid eye movement (REM) sleep behavior disorder (RBD) has an incidence of 15-47% in all PD patients. Prion proteins (PrPs), which are expressed in both neurons and glial cel.. Read More»

Genet. Mol. Res. 16(1): gmr16019022

DOI: 10.4238/gmr16019022

Plant Genetics   Research Article
Genetic diversity of Cajazeira (Spondias mombin L.) in three geographic regions

Authors: B.M. Silva, A.A.B. Rossi, A.V. Tiago, K.F.M. Schmitt, J.F.E. Dardengo and S.A.M. Souza

Cajazeira (Spondias mombin L.), of the family Anacardiaceae, is a species of fruit tree found in the Amazon region with fruits that have excellent prospects for commercial use. We aimed to evaluate the genetic diversity within and among natural populations of S. mombin, with natural occurrence in northern Mato Grosso State, by.. Read More»

Genet. Mol. Res. 16(1): gmr16018946

DOI: 10.4238/gmr16018946

Human Genetics   Research Article
Mitochondrial DNA insertions in the nuclear Capra hircus genome

Authors: F.Y. Ning, J. Fu and Z.H. Du

Nuclear mitochondrial pseudogenes (numts), originating from mtDNA insertions into the nuclear genome, have been detected in many species. However, the distribution of numts in the newly published nuclear genome of domestic goat (Capra hircus) has not yet been explored. We used the entire goat mtDNA sequence and nuclear genome,.. Read More»

Genet. Mol. Res. 16(1): gmr16018266

DOI: 10.4238/gmr16018266

Human Genetics   Research Article
Correlation-based linear discriminant classification for gene expression data

Authors: M. Pan and J. Zhang

Microarray gene expression technology provides a systematic approach to patient classification. However, microarray data pose a great computational challenge owing to their large dimensionality, small sample sizes, and potential correlations among genes. A recent study has shown that gene-gene correlations have a positive effe.. Read More»

Genet. Mol. Res. 16(1): gmr16019357

DOI: 10.4238/gmr16019357

Human Genetics   Research Article
P2X7 receptor in the hippocampus is involved in gp120-induced cognitive dysfunction

Authors: Y. Liu, G.Q. Chen, B.Y. Liu, Q. Chen, Y.M. Qian, S.S. Qin, C.L. Liu and C.S. Xu

To investigate the role of the P2X7 receptor in learning and memory dysfunction induced by HIV-1 envelope glycoprotein gp120 (gp120), we established HIV-1-associated dementia (HAD) animal models by intracerebroventricular (ICV) infusion of gp120 in rats. We observed gp120-induced cognitive dysfunction in the radial arm water m.. Read More»

Genet. Mol. Res. 16(1): gmr16019356

DOI: 10.4238/gmr16019356

Plant Genetics   Research Article
Construction and transformation of expression vector containing Panax japonicus SS gene

Authors: L. Zhang and T.T. Wang

Panax japonicus C.A. Meyer, a perennial herb belonging to the Araliaceae ginseng genus, is one of the seven rare and endangered Chinese medical herbs. By cloning the SS segment, the expression vectors pCXSN-PjSS and pCXSN-antiPjSS were constructed and introduced into Agrobactria LBA4404, which is used for engineering bacteria... Read More»

Genet. Mol. Res. 16(1): gmr16019341

DOI: 10.4238/gmr16019341

Plant Genetics   Research Article
Analysis of the genetic diversity of Lonicera japonica Thumb. using inter-simple sequence repeat markers

Authors: H.Y. He, D. Zhang, H. Qing and Y. Yang

Inter-simple sequence repeats (ISSRs) were used to analyze the genetic diversity of 21 accessions obtained from four provinces in China, Shandong, Henan, Hebei, and Sichuan. A total of 272 scored bands were generated using the eight primers previously screened across 21 accessions, of which 267 were polymorphic (98.16%). Genet.. Read More»

Genet. Mol. Res. 16(1): gmr16019338

DOI: 10.4238/gmr16019338