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Microbial Genetics   Research Article
Multivariate approach in popcorn genotypes using the Ward-MLM strategy: morpho-agronomic analysis and incidence of Fusarium spp

Authors: R.N.F. Kurosawa, A.T. do Amaral Junior, F.H.L. Silva, A. dos Santos,M. Vivas, S.H. Kamphorst and G.F. Pena

The multivariate analyses are useful tools to estimate the genetic variability between accessions. In the breeding programs, the Ward-Modified Location Model (MLM) multivariate method has been a powerful strategy to quantify variability using quantitative and qualitative variables simultaneously. The present study was proposed.. Read More»

Genet. Mol. Res. 16(1): gmr16019528

DOI: 10.4238/gmr16019528

Human Genetics   Review Article
Genetic tests for low- and middle-income countries: a literature review

Authors: P.E. Maltese, E. Poplavskaia, I. Malyutkina, F. Sirocco, A. Bonizzato, N. Capodicasa, S.Y. Nicoulina, A. Salmina, N. Aksutina, M. Dundar, T. Beccari, S. Cecchin and M. Bertelli

The aim of this review is to describe a series of ten genetic diseases with Mendelian inheritance pattern in people of low- or middle-income countries, which can be easily identified with simple and affordable methods. Recent information shows that although genetic diseases account for more than 10% of infant mortality in such.. Read More»

Genet. Mol. Res. 16(1): gmr16019466

DOI: 10.4238/gmr16019466

Plant Genetics   Research Article
Analysis of the cytochrome c oxidase subunit II (COX2) gene in giant panda, Ailuropoda melanoleuca

Authors: S.S. Ling, Y. Zhu, D. Lan, D.S. Li, H.Z. Pang, Y. Wang, D.Y. Li, R.P. Wei, H.M. Zhang, C.D. Wang and Y.D. Hu

The giant panda, Ailuropoda melanoleuca (Ursidae), has a unique bamboo-based diet; however, this low-energy intake has been sufficient to maintain the metabolic processes of this species since the fourth ice age. As mitochondria are the main sites for energy metabolism in animals, the protein-coding genes involved in mitochond.. Read More»

Genet. Mol. Res. 16(1): gmr16019158

DOI: 10.4238/gmr16019158

Human Genetics   Research Article
Dynamics of 45S rDNA sites in the cell cycle: fragile sites and chromosomal stability in Lolium and Festuca

Authors: L.C. Rocha, G.A. Silva, F.O. Bustamante, R.A.D. Silveira,A. Mittlemann and V.H. Techio

Analyses carried out with fluorescence in situ hybridization (FISH) in C-metaphases of the Lolium-Festuca complex have shown the occurrence of spontaneous fragile sites (FSs) in 45S rDNA regions. FSs are expressed as gaps but they do not result in breaks or chromosomal fragments in these species. These gaps have high DNA conde.. Read More»

Genet. Mol. Res. 16(1): gmr16019156

DOI: 10.4238/gmr16019156

Human Genetics   Research Article
Next-generation sequencing analysis of the ARMS2 gene in Turkish exudative age-related macular degeneration patients

Authors: H. Bardak, M. Gunay, Y. Ercalik, Y. Bardak, H. Ozbas and O. Bagci

Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. It is a complex disease with both genetic and environmental risk factors. To improve clinical management of this condition, it is important to develop risk assessment and prevention strategies for environmental influences, and esta.. Read More»

Genet. Mol. Res. 16(1): gmr16019135

DOI: 10.4238/gmr16019135

Human Genetics   Research Article
An experimental study on the use of icariin for improving thickness of thin endometrium

Authors: A.W. Le, Z.H. Wang, X.Y. Dai, T.H. Xiao, R. Zhuo, B.Z. Zhang, Z.L. Xiao and X.J. Fang

This study aimed to investigate the effect of icariin (ICA) on thin endometrium in a rat model. To this end, 6- to 8-week-old female Sprague Dawley rats (105) were randomly divided into 7 groups: untreated, vehicle-treated (lavage with NaCl), high-dose ICA (lavage with ICA at 200 mgâÂ?Â?kg-1âÂ?Â?day-1), medium-dose ICA (lava.. Read More»

Genet. Mol. Res. 16(1): gmr16019126

DOI: 10.4238/gmr16019126

Animal Genetics   Research Article
Effects of feeding conditions on gene expression in chicken breast muscle

Authors: G.L. Gao, C. Wang, X.Z. Zhao, H.W. Wang, Q. Li, J. Li, K.S. Zhang, H. Zhong and Q.G. Wang

Chicken meat quality is becoming increasingly important among breeders and consumers. To understand the effect of feeding conditions on chicken meat quality, we investigated the profiles of genes expressed in chicken breast muscle. Using RNA sequencing, we identified 336, 321, and 387 differentially expressed genes among Cheng.. Read More»

Genet. Mol. Res. 16(1): gmr16019119

DOI: 10.4238/gmr16019119

Plant Genetics   Research Article
Genetic diversity of Casearia sylvestris populations in remnants of the Atlantic Forest

Authors: F.L. Araujo, M.V.B.M. Siqueira, C. Grando, J.P.G. Viana, J.B. Pinheiro, A. Alves-Pereira, J.B. Campos, P.H.S. Brancalion and M.I. Zucchi

Guaçatonga (Casearia sylvestris) is a native plant of the Atlantic Forest, with high medicinal potential and relevance for reforestation programs. The aim of this study was to characterize, with microsatellite markers, two populations of C. sylvestris from remaining areas of the Atlantic Forest in the State of Sã.. Read More»

Genet. Mol. Res. 16(1): gmr16019105

DOI: 10.4238/gmr16019105