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Animal Genetics   Research Article
Transfer and expression of the rabbit defensin NP-1 gene in lettuce (Lactuca sativa)

Authors: D. Song, X. Xiong, W.F. Tu, W. Yao, H.W. Liang, F.J. Chen and Z.Q. He

Lettuce (Lactuca sativa L.) is an annual plant of the daisy family, Asteraceae, with high food and medicinal value. However, the crop is susceptible to several viruses that are transmitted by aphids and is highly vulnerable to post-harvest diseases, as well as insect and mammal pests and fungal and bacterial diseases. Here, th.. Read More»

Genet. Mol. Res. 16(1): gmr16019333

DOI: 10.4238/gmr16019333

Plant Genetics   Research Article
Cytotoxicity evaluation of the whole protein extract from Bar-transgenic rice on Mus musculus lymphocytes

Authors: X.B. Lu

With the expanding demand for genetically modified (GM) rice, its safety evaluation is of great significance. Therefore, this study was carried out to assess the acute cytotoxicity of the whole protein extract from GM rice Bar68-1 in Mus musculus lymphocytes in vitro. Cell viability was determined by Cell Counting Kit-8 (CCK-8.. Read More»

Genet. Mol. Res. 16(1): gmr16019331

DOI: 10.4238/gmr16019331

Human Genetics   Research Article
Protective role of +294 T/C (rs2016520) polymorphism of PPARD in Mexican patients with colorectal cancer

Authors: M.A. Rosales-Reynoso, L.I. Wence-Chavez, A.R. Arredondo-Valdez,S. Dumois-Petersen, P. Barros-N�º�±ez, M.P. Gallegos-Arreola, S.E. Flores-Mart�­nez and J. S�¡nchez-Corona

PPARD encodes for peroxisome proliferator-activated receptor delta, which plays a significant role in controlling lipid metabolism, atherosclerosis, inflammation, cancer growth, progression, and apoptosis. Accumulated evidence suggests that the polymorphism rs2016520 in PPARD is associated with lipid metabolism, obesity, metab.. Read More»

Genet. Mol. Res. 16(1): gmr16019324

DOI: 10.4238/gmr16019324

Plant Genetics   Research Article
Association among agro-industrial traits and simultaneous selection in sweet sorghum

Authors: P.S.S. Leite, T.G. Fagundes, J.A.R. Nunes, R.A.C. Parrella,N.N.L. Dur�£es and A.T. Bruzi

Sweet sorghum has emerged as an alternative crop for ethanol yield. The breeding of this crop is performed to obtain cultivars with high ethanol yield, which necessarily requires associating favorable phenotypes for multiple traits. Therefore, the aims of this study were to investigate the association between agro-industrial t.. Read More»

Genet. Mol. Res. 16(1): gmr16019318

DOI: 10.4238/gmr16019318

Plant Genetics   Research Article
Genetic analysis and identification of SSR markers associated with rice blast disease in a BC2F1 backcross population

Authors: N. Hasan, M.Y. Rafii, H. Abdul Rahim, S.A. Nusaibah, N. Mazlan and S. Abdullah

Rice (Oryza sativa L.) blast disease is one of the most destructive rice diseases in the world. The fungal pathogen, Magnaporthe oryzae, is the causal agent of rice blast disease. Development of resistant cultivars is the most preferred method to achieve sustainable rice production. However, the effectiveness of resistant cult.. Read More»

Genet. Mol. Res. 16(1): gmr16019280

DOI: 10.4238/gmr16019280

Human Genetics   Research Article
A rare case of a boy with de novo micro duplication at 5q35.2q35.3 from central Brazil

Authors: F.G. Reis, I.P. Pinto, L.B. Minasi, A.V. Melo, D.M. da C. Cunha, C.L. Ribeiro, C.C. da Silva, D. de M. Silva and A.D. da Cruz2,3,4,5

Genomic disorders are genetic diseases that are caused by rearrangements of chromosomal material via deletions, duplications, and inversions of unique genomic segments at specific regions. Such rearrangements could result from recurrent non-allelic homologous recombination between low copy repeats. In cases where the breakpoin.. Read More»

Genet. Mol. Res. 16(1): gmr16019197

DOI: 10.4238/gmr16019197

Human Genetics   Research Article
Effect of pregnancy on the proliferation of rat adipose-derived stem cells

Authors: J.N. Li, Y. Zhang, Y.F. Wang and J.Y. Chen

Stem cell therapy faces many problems including poor survival rates and low viability. Enhancing the biological functions of stem cells improves efficacy of therapies. Estrogen, whose levels are elevated during pregnancy, affects the properties of bone marrow mesenchymal stem cells. Evidence suggests that adipose-derived stem .. Read More»

Genet. Mol. Res. 16(1): gmr16019059

DOI: 10.4238/gmr16019059

Human Genetics   Research Article
GRK2 desensitizes flow-induced responses in osteoblasts

Authors: Y. Xing, Y. Gu, X. Shan, L. Wang and J. You

Bone desensitization after mechanical loading is essential for bone to adapt to its mechanical environment. However, the desensitization mechanism is unknown. Previous studies suggest that G protein-coupled receptors (GPCRs), including P2Y and parathyroid hormone receptors, play important roles in osteoblast mechanobiology. Th.. Read More»

Genet. Mol. Res. 16(1): gmr16019363

DOI: 10.4238/gmr16019363