Table of Contents | Genet. Mol. Res.2016(1)
Vascular endothelial growth factor as an angiogenesis biomarker for the progression of autosomal dominant polycystic kidney disease
Authors: D.P. Martins1, M.A. Souza1, M.E. Lopes Baitello1, V. Nogueira1, C.I. Ferreira Oliveira1, M.A. de Souza Pinhel1, H.C. Caldas2, M.A. Filho2 and D.R. Silva Souza1
Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary nephropathy characterized by abnormal growth of epithelial cells. Genetic factors, including the vascular endothelial growth factor (VEGF) gene, play an important role in its progression. The main aim of this study was to evaluate the influence of VEGF-C936T polymorphism in the developme.. Read More»
Genet. Mol. Res. 15(1): gmr.15017623
DOI: 10.4238/gmr.15017623
Distribution of food-borne Staphylococcus aureus enterotoxin genes
Authors: W.D. Hu
We identified and analyzed 5 new-type enterotoxin genes, including SEj, SEl, SEq, SEm, and SEr, to explore the distribution of 5 enterotoxin genes in Staphylococcus aureus of different origins as well as their correlations and differences. We examined the distribution of the S. aureus enterotoxin genes and their pathogenic mechanisms. A total of 660 speci.. Read More»
Genet. Mol. Res. 15(1): gmr.15016084
DOI: 10.4238/gmr.15016084
Molecular characterization, tissue expression profile, and single nucleotide polymorphism analysis of the periostin gene in swine
Authors: D. Xu, H.M. Ma and D.F. Xiao
Periostin, also called osteoblast-specific factor 2, is an important regulator of bone, cardiac development, and wound healing. A recent study revealed that periostin plays an important role in tumor development and is upregulated in a wide variety of cancers. However, little is known about periostin in swine. Therefore, the cDNA sequence of the porcine p.. Read More»
Genet. Mol. Res. 15(1): gmr.15017187
DOI: 10.4238/gmr.15017187
Sequence analysis of the S1PR1 gene in river buffalo
Authors: N.B. Stafuzza1,2, B.C.M. Naressi1, M.M. Borges1 and M.E.J. Amaral-Trusty1
Recent developments in methodologies for genomic analyses have enabled a significant advance in understanding of the river buffalo genome. The S1PR1 gene has been mapped to buffalo chromosome 6 and bovine chromosome 3; this gene is of interest as it is a candidate for marbling in meat, an important economic trait. Here, we performed next generation sequen.. Read More»
Genet. Mol. Res. 15(1): gmr.15016363
DOI: 10.4238/gmr.15016363
Genomic breeding value prediction for simple maize hybrid yield using total effects of associated markers, under different imbalance levels and environments
Authors: N.F. Cantelmo1, R.G. Von Pinho2 and M. Balestre3
The main objective of a maize breeding program is to generate hybrid combinations that are more productive than those pre-existing in the market. However, the number of parents, and consequently the number of crosses, increases so rapidly that the phenotypic evaluation of all the possible combinations becomes economically and technically infeasible. In th.. Read More»
Genet. Mol. Res. 15(1): gmr.15017232
DOI: 10.4238/gmr.15017232
Effects of hyperbaric oxygen on the Nrf2 signaling pathway in secondary injury following traumatic brain injury
Authors: X.E. Meng, Y. Zhang, N. Li, D.F. Fan, C. Yang, H. Li, D.Z. Guo and S.Y. Pan
We investigated the effects of hyperbaric oxygen treatment on the Nrf2 signaling pathway in secondary injury following traumatic brain injury, using a rat model. An improved Feeney freefall method was used to establish the rat traumatic brain injury model. Sixty rats were randomly divided into three groups: a sham surgery group, a traumatic brain injury g.. Read More»
Genet. Mol. Res. 15(1): gmr.15016933
DOI: 10.4238/gmr.15016933
Identification of a Panax ginseng fruit fingerprint by HPLC-ESI-MS
Authors: H.F. Zhao1, F.F. Xu2, Y.T. Guo1 and H. Mi1
Over many years, parts of Panax ginseng (root and rhizome) have been identified and applied for medical purposes as traditional Chinese herbal medicine. Recently, research has indicated that ginseng fruit also contains similar compounds and is as rich as the other parts of the ginseng. This discovery may dramatically improve the efficient of outputs deriv.. Read More»
Genet. Mol. Res. 15(1): gmr.15017235
DOI: 10.4238/gmr.15017235
shRNA inhibits the expression of chicken telomerase reverse transcriptase in MDCC-MSB1 cells
Authors: N. Jiang, X.B. Zheng, Z.Y. Zhao, Z.G. Qin and T.J. Liu
Here, we investigated the effects of blocking chicken telomerase reverse transcriptase (chTERT) in MDCC-MSB1 cells, using small-hairpin RNAs (shRNAs) to interfere with gene expression. shRNAs specific to chTERT mRNA were designed, cloned into DNA plasmid vectors, and transfected into MDCC-MSB1 cells. The transfected chTERT RNAs were expressed by the RNA p.. Read More»
Genet. Mol. Res. 15(1): gmr.15016979
DOI: 10.4238/gmr.15016979