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Human Genetics   Research Article
Association between ERCC1 and ERCC2 polymorphisms and breast cancer risk in a Chinese population

Authors: R. Zhao and M.F. Ying

We conducted a case-control study to investigate the role of ERCC1 rs3212986 and ERCC2 rs13181 gene polymorphisms in the development of breast cancer. Between March 2012 and March 2014, a total of 242 newly diagnosed breast cancer patients with histopathologically confirmed primary breast cancer and 242 healthy controls were recruited. Genotyping of ERCC1.. Read More»

Genet. Mol. Res. 15(1): gmr.15017263

DOI: 10.4238/gmr.15017263

Plant Genetics   Research Article
Transcriptome analysis and anthocyanin-related genes in red leaf lettuce

Authors: Y.Z. Zhang*, S.Z. Xu*, Y.W. Cheng, H.Y. Ya and J.M. Han

This study aimed to analyze the transcriptome profile of red lettuce and identify the genes involved in anthocyanin accumulation. Red leaf lettuce is a popular vegetable and popular due to its high anthocyanin content. However, there is limited information available about the genes involved in anthocyanin biosynthesis in this species. In this study, trans.. Read More»

Genet. Mol. Res. 15(1): gmr.15017023

DOI: 10.4238/gmr.15017023

Human Genetics   Research Article
Genetic analyses of the major and minor locus groups of bacterial wilt resistance in tobacco using a diallel cross design

Authors: Y.L. Qian1*, J. Chen2*, J.J. Dong3, Z.C. Wu4, Y.H. Liu3, B.Y. Xue3, F.W. Shao3 and X.Y. Sun1

Tobacco germplasm samples with various levels of resistance to bacterial wilt were selected to construct F1 combinations of parental inbred lines and orthogonal diallel crosses using samples collected in 2009 (15 germplasms), 2010 (15 germplasms), and 2011 (16 germplasms). A total of 1/2P (P + 1) experimental materials were used for analysis. Based on the.. Read More»

Genet. Mol. Res. 15(1): gmr.15017223

DOI: 10.4238/gmr.15017223

Animal Genetics   Research Article
Transcriptional analysis of atrial and ventricular muscles from rats

Authors: Y. Zhi3*, Z. Cao2*, Q.H. Li1, X.L. Li1, Y. Sun1, T. Zhang1 and Q. Zhang1

Previous studies have used microarray technology to explore gene expression differences between the atrium and the ventricle. However, selection criteria for the differentially expressed genes (DEGs) based only on either the fold change or the P value in these studies. Here, we aim to further identify the DEGs by setting a P value threshold of 2, which ma.. Read More»

Genet. Mol. Res. 15(1): gmr.15017330

DOI: 10.4238/gmr.15017330

Microbial Genetics   Research Article
Population genetic analysis and trichothecene profiling of Fusarium graminearum from wheat in Uruguay

Authors: D. Pan1, A. Mionetto1, N. Calero1, M.M. Reynoso2, A. Torres2 and L. Bettucci1

Fusarium graminearum sensu stricto (F. graminearum s.s.) is the major causal agent of Fusarium head blight of wheat worldwide, and contaminates grains with trichothecene mycotoxins that cause serious threats to food safety and animal health. An important aspect of managing this pathogen and reducing mycotoxin contamination of wheat is knowledge regarding .. Read More»

Genet. Mol. Res. 15(1): gmr.15017270

DOI: 10.4238/gmr.15017270

Animal Genetics   Research Article
Molecular characterization and tissue expression profile of porcine Ephrin-B2

Authors: D. Xu and H.M. Ma

Ephrin-B2 (EFNB2) is a signaling molecule that plays an important role in cell adhesion, proliferation, and migration in humans. However, little is known about this molecule in pigs. In order to investigate whether EFNB2 is associated with the skeletal muscle in pigs, we cloned the full-length cDNA of EFNB2 (GenBank accession No. KF500033) from the longis.. Read More»

Genet. Mol. Res. 15(1): gmr.15017463

DOI: 10.4238/gmr.15017463

Animal Genetics   Research Article
Relationship between multiple paternity and reproductive parameters for Podocnemis sextuberculata (Testudines Podocnemididae) in the Trombetas River, Brazil

Authors: F.P. Freda1, V.C.D. Bernardes1, C.C. Eisemberg3, C. Fantin2 and R.C. Vogt1

Genetic studies of multiple paternity are a valuable tool to gain information on the reproductive biology of turtles. We analyzed paternity type in Podocnemis sextuberculata and related number of fathers per nest to nesting period (beginning, middle, or end of nesting season); clutch size (number of eggs); female size; and hatchling success. Females were .. Read More»

Genet. Mol. Res. 15(1): gmr.15017335

DOI: 10.4238/gmr.15017335

Medical Genetics   Research Article
Association of interleukin-8 gene polymorphisms in HIV patients with opportunistic infections in Limpopo Province, South Africa

Authors: G.A. Dzhivhuho1, T.C. Nangammbi2 and A. Samie3

Opportunistic infections (OIs) are common among human immunodeficiency virus (HIV) patients; however, genetic susceptibility to these infections has not been studied. Recent studies have shown that interleukin-8 (IL-8) A/T genotype carriers are more susceptible to a variety of diseases. In this study, we showed the effects of IL-8 gene polymorphisms on OI.. Read More»

Genet. Mol. Res. 15(1): gmr.15017466

DOI: 10.4238/gmr.15017466