Y.S. Wang

Association of monocyte chemoattractant protein-1 rs1024611 and telomerase rs2736100 polymorphisms with susceptibility to pulmonary tuberculosis in Han Chinese population

• G.H. Cheng
• X.L. Wang
• X.T. Yuan
• Q. Xin
• Q. Sun
• K.L. Li
• C. Sun
• Z.M. Lin
• Y. Luan
• Y.S. Wang
• F. Kong
• D.W. Xu

Pulmonary tuberculosis (PTB) is caused by Mycobacterium tuberculosis infection and accumulated evidence reveals the genetic context of its infection phenotypes. Monocyte chemoattractant protein-1 (MCP-1) rs1024611 variant is shown to be associated with PTB susceptibility in some studies, but significant disparities exist. In addition, telomerase plays a key role in .. Read More»

Genet. Mol. Res. 16(3): gmr16039697

DOI: 10.4238/gmr16039697

Long-term survival of non-small-cell lung cancer patients with EGFR inhibitor treatment

M.X. Zhang1,2, W. Tan1, R.X. Zhang3, Y.L. Tian1, H.M. Gao1,2, Z. Gao1, N. Zhang1, J.Q. Zhao1, Y.F. Jia1,2 and Y.S. Wang1,2

The epidermal growth factor receptor (EGFR) inhibitors gefitinib and erlotinib are effective in the treatment of advanced non-small-cell lung cancer (NSCLC), but the median survival of patients is short. Here, we describe 2 patients with NSCLC receiving conventional chemotherapy and alternative treatment with gefitinib or erlotinib as second-line therapy. The first patient was alive at 8 years .. Read More»

Genet. Mol. Res. 13(4):

No association of polymorphisms in the suppressor of cytokine signaling (SOCS)-3 with rheumatoid arthritis in the Chinese Han population

L.P. Sun*, X.L. Ma*, H.X. Liu, Y.S. Wang and X.F. Li

Suppressor of cytokine signaling (SOCS)-3 is a key negative regulator of cytokine signaling that inhibits the JAK/STAT signal transduction pathway; there are reports describing its role in attenuating arthritis through SOCS-3 overexpression. We examined the relationship between polymorphisms in the coding sequence and promoter region of SOCS-3 and rheumatoid arthrit.. Read More»

Genet. Mol. Res. 9(3): vol9-3gmr914

DOI: 10.4238/vol9-3gmr914

Analysis of the 19 Y-STR and 16 X-STR loci system in the Han population of Shandong province, China

H.M. Gao, C. Wang, S.Y. Han, S.H. Sun, D.J. Xiao, Y.S. Wang, C.T. Li, M.X. Zhang

H.M. Gao C. Wang S.Y. Han S.H. Sun D.J. Xiao Y.S. Wang C.T. Li M.X. Zhang The sex-linked short tandem repeats (STR), Y-STR and X-STR, are important for autosomal STRs in forensic paternity testing. We evaluated the forensic parameters of 19 Y-STRs and 16 X-STRs in the Han population of Shandong province, China. A Goldeneye 20Y kit (DYS39.. Read More»

Genet. Mol. Res. 16(1): gmr16019573

DOI: 10.4238/gmr16019573

Association of interleukin-1β -511C/T promoter polymorphism with COPD risk: a meta-analysis

Y.S. Wang, L. Liu, X.Y. Xu, J.L. Wang, H. Zhou, T.L. Li and Z.A. Liang

Studies examining the role of interleukin (IL)-1β -511C/ T promoter polymorphism in the pathogenesis of chronic obstructive pulmonary disease (COPD) have shown inconsistent results. This metaanalysis was performed to assess the association between the IL-1β -511C/T promoter polymorphism and COPD susceptibility. Published case-control, cross-sectional, and cohort studies from Pubmed, E.. Read More»

Genet. Mol. Res. 14(2): 2015.May.4.5

DOI: 10.4238/2015.May.4.5

Identification of sequence-related amplified polymorphism markers linked to the red leaf trait in ornamental kale (Brassica oleracea L. var. acephala)

Y.S. Wang, Z.Y. Liu, Y.F. Li, Y. Zhang, X.F. Yang and H. Feng

Artistic diversiform leaf color is an important agronomic trait that affects the market value of ornamental kale. In the present study, genetic analysis showed that a single-dominant gene, Re (red leaf), determines the red leaf trait in ornamental kale. An F2 population consisting of 500 individuals from the cross of a red leaf double-haploid line ‘D05â€&Ac.. Read More»

Genet. Mol. Res. 12(2): 2013.April.2.3

DOI: 10.4238/2013.April.2.3

Risk analysis of duo parentage testing with limited STR loci

M.X. Zhang, H.M. Gao, S.Y. Han, Y. Liu, Y.L. Tian, S.H. Sun, D.J. Xiao, C.T. Li and Y.S. Wang,

The aim of this study was to evaluate whether the Goldeneye 20A system (containing 19 short tandem repeats) can avert the shortage of duo parentage tests. Among routine cases typed by the Identifiler system, we identified 42 motherless cases, 2 fatherless cases, and 34 trio cases containing 1 locus mismatch and 4 motherless cases with 2 locus mismatches. One true tr.. Read More»

Genet. Mol. Res. 13(1): http://dx.doi.org/2014.February.27.2

DOI: http://dx.doi.org/10.4238/2014.February.27.2