Medical Genetics
Genetic diversity studies of Brazilian garlic cultivars and quality control of garlic-clover production
Authors: G.S.C. Buso, M.R. Paiva, A.C. Torres, F.V. Resende, M.A. Ferreira, J.A. Buso and A.N. Dusi
The garlic cultivars grown in Brazil evolved from somatic mutations and clone selection by breeding programs and by the introduction of germplasm from other countries. Morphological characters have been used to differentiate these cultivars. Two hundred and six random amplified polymorphic DNA markers were utilized for a diver.. Read More»
- Genet. Mol. Res. 7(2):
Novel representation of RNA secondary structure used to improve prediction algorithms
Authors: Q. Zou, C. Lin, X.-Y. Liu, Y.-P. Han, W.-B. Li and M.-Z. Guo
We propose a novel representation of RNA secondary structure for a quick comparison of different structures. Secondary structure was viewed as a set of stems and each stem was represented by two values according to its position. Using this representation, we improved the comparative sequence analysis method results and the min.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1181
- DOI:
- 10.4238/vol10-3gmr1181
Schistosome/mollusk: genetic compatibility
Authors: A.L.D. Oliveira, D. Da Silva, E.M. Zanotti-Magalhaes,A.Z. Abdel-Hamid, J.T. Ribeiro-Paes
Schistosomiasis remains one of the most prevalent parasitic infections and has significant economic and public health consequences in many developing countries. Economic development and improvement in standard of living in these countries are dependent on the elimination of this odious disease. For the control of Schistosomias.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr444
- DOI:
- 10.4238/vol7-2gmr444
Response to treatment with imatinib mesylate in previously treated chronic-phase chronic myeloid leukemia patients in a hospital in Brazil
Authors: C.A.P. Silveira, M.B. Daldegan and I. Ferrari
We analyzed the results of treatment with imatinib mesylate in 70 patients with chronic-phase chronic myeloid leukemia who had previously been treated (with second-line or higher imatinib), many of them in a late chronic phase. The median follow-up period was 60.5 months (range 3-100 months). Our objective was to assess the ef.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1073
- DOI:
- 10.4238/vol10-3gmr1073
Evaluation of serum HGF and CK18 levels in patients with esophageal cancer
Authors: N. Kilic-Baygutalp, N. Ozturk, E. Orsal-Ibisoglu, B. G�¼ndogdu, F.B. Ozgeris, N. Bakan, E. Bakan and A.F. Kilic
Cytokeratins are thought to play a role in apoptosis. Cytokeratin 18 (CK18) is involved in the formation of intracellular cytoskeleton, and has been considered a promising apoptosis marker in gastrointestinal carcinomas. Growth factors, including hepatocyte growth factor (HGF), may provide a microenvironment for malignant cell.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038583
- DOI:
- 10.4238/gmr.15038583
ABO genotyping in leukemia patients reveals new ABO variant alleles
Authors: M.C.Z. Novaretti, A.E. Domingues, R. Manhani, E.M. Pinto, P.E. Dorlhiac-Llacer and D.A.F. Chamone
The ABO blood group is the most important blood group system in transfusion medicine and organ transplantation. To date, more than 160 ABO alleles have been identified by molecular investigation. Almost all ABO genotyping studies have been performed in blood donors and families and for investigation of ABO subgroups detected serologically. The aim of the .. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr401
- DOI:
- 10.4238/vol7-1gmr401
Genetic and correlation analysis of oleoresin chemical components in slash pine
Authors: S. Zhang, J. Jiang and Q. Luan
This is the first comprehensive study of the genetic analysis of the majority of oleoresin components of slash pine (Pinus elliottii). Pine oleoresin, the resin secreted from the pine tree, is a raw material widely used in industrial products. The objective of this study was to explore the genetic variation and correlation bet.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038982
- DOI:
- 10.4238/gmr.15038982
Expression of aquaporin-4 in human supratentorial meningiomas with peritumoral brain edema and correlation of VEGF with edema formation
Authors: P. Wang, R.Y. Ni , M.N. Chen, K.J. Mou, Q. Mao and Y.H. Liu
Peritumoral brain edema is a common complication of meningiomas. It is believed that vascular endothelial growth factor (VEGF), as an angiogenic factor, plays a vital role in edema formation. Aquaporin-4 (AQP4) is a small integral membrane protein that regulates water in the normal brain. However, the expression of AQP4 and it.. Read More»
- Genet. Mol. Res. 10(3):
Discrimination of common bean cultivars using multiplexed microsatellite markers
Authors: P.C.B. Cardoso, C. Brondani, I.P.P. Menezes, P.A.M.R. Valdisser, T.C.O. Borba,, M.J. Del Peloso and R.P. Vianello
Analysis of DNA polymorphisms allows for the genetic identification and precise discrimination of species with a narrow genetic base such as common bean. The primary objectives of the present study were to molecularly characterize commercial common bean varieties developed at various research institutions using microsatellite .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.1
- DOI:
- 10.4238/2014.March.24.1
Association between �²1 adrenergic receptor gene Arg389Gly polymorphism and risk of heart failure: a meta-analysis
Authors: S.T. Ma, W. Zhao,B. Liu, R.Y. Jia, C.J. Zhao and L.Q. Cui
Numerous studies have evaluated the association between Arg389Gly polymorphism in the β1 adrenergic receptor gene and heart failure risk. However, the specific association is still controversial. We performed a meta-analysis of all case-control studies that evaluated the association between Arg389Gly polymorphism and heart failure in humans. Studies .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.9
- DOI:
- 10.4238/2015.June.1.9