Medical Genetics
Effect of antagonistic yeast XL-1 on resistance-associated enzyme activities in postharvest cantaloupe
Authors: C.-H. Shan, W. Chen, H. Zhang, F.-X. Tang and J.-M. Tong
The effect of the antagonistic yeast XL-1 on resistance-associated enzyme activities in postharvest cantaloupe was studied by inoculating the antagonistic yeast XL-1. Cantaloupes were sterilized, dried in air, and soaked in antagonistic yeast treatment liquid for 30 s. After drying in air, the cantaloupe was stored at room tem.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.15.8
- DOI:
- 10.4238/2014.August.15.8
Evaluation of endovascular abdominal aortic aneurysm repair in nonagenarians
Authors: H.P. Zhang, W. Guo, X.P. Liu, X. Jia, J. Xiong, X.H. Ma, M.H. Zhang and Y.L. Xu
The aim of this study was to investigate the safety and efficacy of endovascular abdominal aortic aneurysm repair (EVAR) in nonagenarians. From May 2003 to March 2011, 12 nonagenarian abdominal aortic aneurysm patients were treated with endovascular repair including two emergencies. The mean age of patients was 92.5 ± 1.6 years (range: 90-95 years).. Read More»
- Genet. Mol. Res. 12(4):
- 2013
- DOI:
- 10.4238/2013
Prediction of disease-related microRNAs by incorporating functional similarity and common association information
Authors: K. Han, P. Xuan2, J. Ding, Z.J. Zhao, L. Hui and Y.L. Zhong
The identification of human disease-related microRNAs (miRNAs) is important for understanding the pathogenesis of diseases, but to do this experimentally is a costly and time-consuming process. Computational prediction of disease-related miRNA candidates is a valuable complement to experimental studies. It is essential to deve.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.5
- DOI:
- 10.4238/2014.March.24.5
Effects of ACE polymorphisms and other risk factors on the severity of coronary artery disease
Authors: A.I. Guney, D. Ergec, D. Kirac, H. Ozturhan, M. Caner, G. Koc, C. Kaspar, K. Ulucan and M. Agirbasli
Coronary artery disease (CAD) is a multifactorial disease influenced by genetic and environmental factors. Major risk factors of CAD are hypertension, hyperlipidemia, smoking, family history and obesity. Also polymorphisms in the angiotensin-I converting enzyme (ACE) gene can associate with CAD. The relationship between ACE polymorphisms and other risk fa.. Read More»
- Genet. Mol. Res. 12(4):
- 2013
- DOI:
- 10.4238/2013
Polymorphisms of three new microsatellite sites of the dystrophin gene
Authors: R.F. Sun, Y.S. Zhu, J.L. Feng, Z. Tian, W.J. Kuang, Y. Liu, H.B. Zhang and S.B. Li
To look for novel microsatellites in the dystrophin gene for the diagnosis of Duchenne muscular dystrophy, candidate microsatellite sites in the dystrophin gene were analyzed with the SSRHunter software and were also genotyped. Among the 15 candidate microsatellite sites, three novel microsatellite sites in the 60th, 30th, and.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr962
- DOI:
- 10.4238/vol10-2gmr962
Modulation of expressivity in PDGFRB-related infantile myofibromatosis: a role for PTPRG?
Authors: N.D. Linhares, M.C.M. Freire, R.G.C.C.L. Cardenas, M. Bahia, E. Puzenat, F. Aubin and S.D.J. Pena
Infantile myofibromatosis is a rare genetic disorder characterized by the development of benign tumors in the skin, muscle, bone, and viscera. The molecular pathogenesis is still incompletely known. An autosomal dominant form had been reported as causally related with mutations in the gene for platelet-derived growth factor re.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.15.11
- DOI:
- 10.4238/2014.August.15.11
Cox-2 gene polymorphism and IL-6 levels in coronary artery disease
Authors: K.K. Ol, B. Agachan, U. Gormus2, B. Toptas and T. Isbir
Coronary artery disease is one of the leading causes of mortality and diabetes mellitus is one of its main risk factors due to microvascular and macrovascular complications, such as atherosclerosis. Atherosclerosis is now known to be an inflammatory process mediated by prostaglandins and several interleukins. As both are impor.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr967
- DOI:
- 10.4238/vol10-2gmr967
Characteristics and clinical significance of lymph node metastases near the recurrent laryngeal nerve from thoracic esophageal carcinoma
Authors: K. Ye, J.H. Xu, Y.F. Sun, J.A. Lin and Z.G. Zheng
This study aimed to evaluate the characteristics of lymph node (LN) metastases from thoracic esophageal carcinoma near the recurrent laryngeal nerve and the influence of these metastases on patient prognosis and to determine the reasonable regional LN dissection range. The clinical data from 120 patients who underwent resectio.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.4
- DOI:
- 10.4238/2014.August.25.4
Establishment of the optimum two-dimensional electrophoresis system of ovine ovarian tissue
Authors: J.L. Jia, L.P. Zhang, J.P. Wu, J. Wang and Q. Ding
Lambing performance of sheep is the most important economic trait and is regarded as a critic factoring affecting the productivity in sheep industry. Ovary plays the most roles in lambing trait. To establish the optimum two-dimensional electrophoresis system (2-DE) of ovine ovarian tissue, the common protein extraction methods.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.26.3
- DOI:
- 10.4238/2014.August.26.3
Racial disparities in the association between diabetes mellitus-associated polymorphic locus rs4430796 of the HNF1�² gene and prostate cancer: a systematic review and meta-analysis
Authors: Y.Z. Xiang, S.B. Jiang, J. Zhao, H. Xiong, Z.L. Cui, G.B. Li and X.B. Jin
Polymorphism 17q12 rs4430796 within HNF1β is a genetic variant associated with both diabetes mellitus and prostate cancer, but findings on the correlations of rs4430796 with prostate cancer risk specifically are not in agreement, especially among diverse populations. To shed some light on the contradictory findin.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.28.3
- DOI:
- 10.4238/2014.August.28.3