Medical Genetics
Vascular endothelial growth factor -634 G/C polymorphism and risk of cancer: an updated meta-analysis
Authors: J.Y. Ban, J.I. Shin and C.-H. Oh
The association between vascular endothelial growth factor (VEGF) gene polymorphisms and risk of cancer has been investigated in several studies published previously; however, the individual results are inconclusive. Therefore, we performed a meta-analysis to establish evidence for an association between the VEGF -634 G/C polymorphism and risk of cancer. .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.11
- DOI:
- 10.4238/2015.October.29.11
Estimation of genetic distance between 10 maize accessions with varying response to different levels of soil moisture
Authors: M. Aslam, F.S. Awan, I.A. Khan and A.I. Khan
Ten maize accessions (NC-9, A50-2, M-14, B-42, NC-3, T-7, N-48-1, B-34, USSR, and WFTMS) were studied to estimate the genetic distance on molecular level by random amplified polymorphic DNA. These accessions were selected on the basis of their variable responses against different levels of moisture. Twenty-five primers were us.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr606
- DOI:
- 10.4238/vol8-4gmr606
RNA applications for endophytic research
Authors: J.C. Polonio, A.D. Polli, J.L. Azevedo and J.A. Pamphile
Endophytic microorganisms, mainly bacteria and fungi, have intrinsic relationships with the host plants, involving complex chemical and genetic communication networks. The relationship among these organisms involves the development of regulatory mechanisms of gene expression that control their development and response to different interactions. Although R.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038879
- DOI:
- 10.4238/gmr.15038879
Inhibitory effects of spironolactone on myocardial fibrosis in spontaneously hypertensive rats
Authors: H. Zhao, D.W. Gu, H.T. Li, Q.F. Ge and G.P. Li
This study evaluated the inhibitory effects of spironolactone, a non-selective aldosterone receptor antagonist, on hypertension-induced myocardial fibrosis. Collagen I and III contents was detected in the myocardial tissue of spontaneously hypertensive rats (SHRs) after spironolactone administration. Twenty male SHRs were assigned to the spironolactone gr.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.August.28.17
- DOI:
- http://dx.doi.org/10.4238/2015.August.28.17
Detecting circulating tumor cells in patients with advanced non-small cell lung cancer
Authors: Y.H. Xu, J. Zhou and X.F. Pan
We explored the expression and clinical significance of circulating tumor cells (CTCs) in patients with advanced non-small cell lung cancer (NSCLC). Sixty-six patients with advanced NSCLC at the Oncology Department of Jinzhou Hospital were selected as an observation group between February and December 2013. Healthy volunteers and 20 benign lung disease pa.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.1.1
- DOI:
- http://dx.doi.org/10.4238/2015.September.1.1
Correlations among copeptin, ischemia-modified albumin, and the extent of myocardial injury in patients with acute carbon monoxide poisoning
Authors: J. Li, J.S. Wang, Z.X. Xie, W.Z. Wang, L. Wang, G.Y. Ma, Y.Q. Li and P. Wang
This study evaluated the relationships among copeptin, ischemia-modified albumin (IMA), and extent of myocardial injury in patients with acute carbon monoxide poisoning (ACOP). A total of 110 patients with different degrees of ACOP were selected as the poisoning group, and 30 healthy individuals as the control group. The levels of troponin I (cTnI), IMA, .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.1.5
- DOI:
- http://dx.doi.org/10.4238/2015.September.1.5
A general review of competition genetic effects with an emphasis on swine breeding
Authors: C.Y. Chen, R.K. Johnson, L.D. Van Vleck, S. Newman
A review of previous studies is presented on estimates of genetic parameters and responses to selection with traditional breeding approaches, on correlations between agonistic behavior and growth performance, and on theoretical frameworks for selection incorporating interactions among individuals and on practical methods for i.. Read More»
- Genet. Mol. Res. 6(3):
Effect of chronic hypoxia on penile erectile function in rats
Authors: D.P. Yu, X.H. Liu and A.Y. Wei
We examined the relationship between chronic hypoxia and erectile dysfunction in rat and its possible pathogenic mechanism. Forty-eight white male adult Sprague-Dawley rats were randomly divided into a test group and a control group. In accordance with the experimental time (2, 6, and 10 weeks), each group was divided into 3 subgroups, with 8 rats in each.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.8.9
- DOI:
- http://dx.doi.org/10.4238/2015.September.8.9
Differentiation of Nijmegen breakage syndrome from Fanconi anemia
Authors: V.B. Rao, K. Ghosh, L. Kerketta, S. Korgaonkar
Nijmegen breakage syndrome (NBS) is a rare auto-somal recessive condition with chromosomal instability. Clinical and biological overlap between Fanconi anemia and ataxia telangiectasia has been reported. We report two cases of NBS born to consanguineous parents. Case one had NBS and Falconi anemia clinical features but relativ.. Read More»
- Genet. Mol. Res. 6(3):
Effect of low temperatures on BAX and BCL2 proteins in rats with spinal cord ischemia reperfusion injury
Authors: P. Zhu, M.Y. Zhao, X.H. Li, Q. Fu, Z.F. Zhou, C.F. Huang, X.S. Zhang, H.L. Huang, Y. Tan, J.X. Li, J.N. Li, S. Huang, M. Ashraf, C. Lu, J.M. Chen, J. Zhuang and H.M. Guo
We evaluated changes in BAX and BCL2 expression levels after spinal cord ischemia/reperfusion injury (SCII) and hypothermia during operations in rats. Eighty rats were divided into four groups: Group A (N = 20, 18°C); Group B (N = 20, 28°C); Group C (N = 20, room temperature); and Group D (N = 20, sham operation control). Spinal cord ischemia was .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.8.10
- DOI:
- http://dx.doi.org/10.4238/2015.September.8.10