Se
Association between GSTM1, GSTT1, and GSTP1 polymorphisms and gastric cancer risk, and their interactions with environmental factors
Authors: Z.H. Chen, J.F. Xian and L.P. Luo
Glutathione S-transferase (GST) is an important member of phase II metabolic enzymes; GSTM1, GSTT1, and GSTP1 belong to three subfamilies of the GST enzyme. Polymorphisms in GSTM1, GSTT1, and GSTP1 could affect detoxification processes, and increase individuals’ susceptibility to cancers. We aimed to investigate the asso.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018877
- DOI:
- 10.4238/gmr16018877
Polymorphic microsatellite loci for Japanese Spanish mackerel (Scomberomorus niphonius)
Authors: L. Lin, L. Zhu, S.-F. Liu, Q.-S. Tang, Y.-Q. Su and Z.-M. Zhuang
We isolated and characterized 21 polymorphic microsatellite loci in Japanese Spanish mackerel (Scomberomorus niphonius) using a (GT)13-enriched genomic library. Forty individuals were collected from Qingdao, China. We found 3 to 24 alleles per locus, with a mean of 8.8. The observed and expected heterozygosities ranged from 0... Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.8.2
- DOI:
- 10.4238/2012.May.8.2
TGF-�²1 and Serpine 1 expression changes in traumatic deep vein thrombosis
Authors: J.W. Mo, D.F. Zhang, G.L. Ji, X.Z. Liu and B. Fan
The objective of this study was to investigate the expression changes of transforming growth factor β1 (TGF-β1) and Serpine 1 in rats with traumatic deep vein thrombosis (DVT). In total, 60 male Sprague Dawley rats were divided into model (N = 50) and control groups (Group A, N = 10). From the model group, 10 rats were randomly selected after mo.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.3
- DOI:
- 10.4238/2015.October.29.3
Association of N-acetyltransferase-2 polymorphism with an increased risk of coronary heart disease in a Chinese population
Authors: J.D. Sun, H. Yuan, H.Q. Hu and H.M. Yu
We investigated the possible correlations between N-acetyltransferase-2 (NAT2) gene polymorphisms and the risk of coronary heart disease (CHD). CHD patients (113) and healthy controls (118) were enrolled from the First People’s Hospital of Yuhang between January 2013 and June 2014. The patients were divided into mild CHD (N = 72) and severe CHD (N =.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016954
- DOI:
- 10.4238/gmr.15016954
Use of simple sequence repeat markers for DNA fingerprinting and diversity analysis of sugarcane (Saccharum spp) cultivars resistant and susceptible to red rot
Authors: U. Hameed, Y.-B. Pan, K. Muhammad, S. Afghan and J. Iqbal
Red rod is an economically important disease of sugarcane caused by the fungus Colletotrichum falcatum. We used a simple sequence repeat (SSR)-based marker system to identify and analyze genetic relationships of red rot resistant and susceptible sugarcane cultivars grown in Pakistan. Twenty-one highly polymorphic SSR markers w.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.8.1
- DOI:
- 10.4238/2012.May.8.1
Effect of high-intensity exercise on interleukin-15 expression in rabbit synovia
Authors: Y.H. Wang, X.D. Li, W.B. Zhu and G.F. Sun
The objective of this study was to examine the effect of high-intensity exercise on interleukin-15 (IL-15) expression in rabbit synovia. We utilized 24 New Zealand white rabbits, which were randomly divided equally into high-intensity exercise and control groups. The former were forced to run for 60 min/day over 4 weeks at the speed of 30 m/min. The histo.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.5
- DOI:
- 10.4238/2015.October.29.5
Development and validation of the first SSR markers for Mimosa scabrella Benth
Authors: F.A. Saiki, A.P. Bernardi, M.S. Reis, H. Faoro, E.M. Souza, F.O. Pedrosa, A. Mantovani and A.F. Guidolin
Mimosa scabrella Benth., popularly known as ‘‘bracatinga’’, is a pioneer and endemic species of Brazil, occurring in Mixed Ombrophilous Forest associated with Brazilian Atlantic Rainforest biomes. It is a fast-growing tree of the Fabaceae family that facilitates the dynamics of ecological succession. SS.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019571
- DOI:
- 10.4238/gmr16019571
Frequency of alterations in the MEFV gene and clinical signs in familial Mediterranean fever in Central Anatolia, Turkey
Authors: G.G. Ceylan, C. Ceylan and E. Ozturk
Familial Mediterranean fever is a recessive autoinflammatory disease that is frequent in Armenians, Jews, Arabs, and Turks. The MEFV gene is responsible for this disease. We looked for MEFV gene variations (polymorphism and mutations) in a population that resides in Central Anatolia, Turkey. DNA was extracted from peripheral b.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.7.4
- DOI:
- 10.4238/2012.May.7.4
Chloroplast diversity of Casearia grandiflora in the Cerrado of Piau� State
Authors: M.F. Costa, A.A. Pereira, J.B. Pinheiro, M.I. Zucchi, A.S.F. Ara�ºjo, R.L.F. Gomes, S.E.S. Valente, M.E.A. Oliveira and A.C.A. Lopes
Casearia grandiflora (Salicaceae) is a typical Cerrado species adapted to disturbed environments, making it useful for restoration projects. Knowledge of genetic diversity is important for establishing conservation strategies for this species. This study aimed to compare chloroplast haplotype diversity and structure of C. gran.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019572
- DOI:
- 10.4238/gmr16019572
Differential expression of hENT1 and hENT2 in colon cancer cell lines
Authors: Y. Liu, T. Zuo, X. Zhu, N. Ahuja and T. Fu
Human equilibrative nucleoside transporters (hENT) 1 and 2, encoded by SLC29A1 and SLC29A2, permit the bidirectional passage of nucleoside analogues into cells and may correlate with clinical responses to chemotherapy in patients with colorectal cancer (CRC). The purpose of this study was to evaluate the expression profiles of.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019549
- DOI:
- 10.4238/gmr16019549