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rs3918242 MMP9 gene polymorphism is associated with myocardial infarction in Mexican patients
Authors: J.M. RodrÃ?Âguez-PÃ?©rez1*, G. Vargas-AlarcÃ?³n1*, R. Posadas-SÃ?¡nchez2,T.X. Zagal-JimÃ?©nez1, R. OrtÃ?Âz-AlarcÃ?³n1, B. Valente-Acosta1, C. Tovilla-ZÃ?¡rate3, C. Nostroza-HernÃ?¡ndez1, O. PÃ?©rez-MÃ?©ndez1 and N. PÃ?©rez-HernÃ?¡ndez1,4
Several studies have demonstrated that matrix metalloproteinases (MMPs) play a major role in atherosclerotic plaque disruption and lead to myocardial infarction (MI). We investigated the association between the MMP1 -1607 1G/2G (rs1799750), MMP3 -1612 5A/6A (rs3025058), and MMP9 -1562 C/T (rs3918242) polymorphisms and the risk of developing MI in a Mexica.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017776
- DOI:
- 10.4238/gmr.15017776
Effects of exogenous protease supplementation on endogenous trypsin activity and gene expression in broilers
Authors: L. Yuan, S.Q. Wang, Z.X. Wang, H. Zhu and K. Huang
Two hundred and forty one-day-old male broiler chickens (Ross-308) were fed corn-soybean basal diets with 0, 40, 80, or 160 mg/kg of an acid protease preparation from 1 to 42 days of age, in order to investigate the effects of an exogenous enzyme on growth performance, pancreatic trypsin activity and mRNA expression. Average daily gain (ADG) was greatest .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.25
- DOI:
- 10.4238/2015.October.28.25
SRAP analysis of DNA base sequence changes in lotus mutants induced by Fe+ implantation
Authors: C.L. Deng R.Y. Qin J. Gao Y.Y. Jia Y.X. Ren W.J. Gao L.D. Lu
Ion implantation, a new biophysically mutagenic technique, has shown great potential for crop breeding. To reveal the mutation effect of low-energy ion implantation on Baiyangdian red lotus, sequence-related amplified polymorphism markers were used to amplify and detect the DNA sequence differences in mutants induced by Fe+ ion implantation. A total of 12.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.3
- DOI:
- 10.4238/2013.February.7.3
Characterization of eight novel microsatellite markers in the green-lipped mussel Perna viridis (Mytilidae)
Authors: Y.Y. Cao Z.B. Li Q.H. Li X.J. Chen L. Chen G. Dai
The green lipped mussel, also known as the Asian green mussel (Perna viridis) is a fast reproducing and valuable food source, but it is also considered an invasive species and can clog and damage pipes and marine equipment. Eight novel polymorphic microsatellite loci for P. viridis were isolated and characterized. Microsatellite polymorphism was evaluated.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.4
- DOI:
- 10.4238/2013.February.7.4
VEGF, eNOS, and ABCB1 genetic polymorphisms may increase the risk of osteonecrosis of the femoral head
Authors: Z.C. Zhou, S.Z. Gu, J. Wu and Q.W. Liang
We investigated the associations between vascular endothelial growth factors (VEGF), endothelial nitric oxide synthase (eNOS), and ATP-binding cassette subfamily B member 1 transporter (ABCB1) polymorphisms and the risk of osteonecrosis of the femoral head (ONFH). Published studies were reviewed and analyzed based on predefined selection criteria. The str.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.31
- DOI:
- 10.4238/2015.October.28.31
Microsatellite markers for genetic studies of the fall armyworm, Spodoptera frugiperda
Authors: V.A.C. Pavinato S. Martinelli P.F. de Lima M.I. Zucchi C. Omoto
We developed six microsatellite markers for the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae). The SSR loci were isolated with enriched genomic library protocol by using native individuals as a genome source for markers. These loci were characterized in 48 individuals and they were tested for the ability to identify candidate migrants excha.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.1
- DOI:
- 10.4238/2013.February.8.1
Polymorphisms of the bovine growth differentiation factor 9 gene associated with superovulation performance in Chinese Holstein cows
Authors: K.Q. Tang W.C. Yang S.J. Li L.-G. Yang
Growth differentiation factor 9 (GDF9) belongs to the transforming growth factor Ã?² superfamily and plays a critical role in ovarian follicular development and ovulation rate. We examined the bovine GDF9 gene polymorphism and analyzed its association with superovulation performance. Based on the sequence of the bovine GDF9 gene, six pairs of primers were d.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.3
- DOI:
- 10.4238/2013.February.8.3
MicroRNA-29a promotes apoptosis of monocytes by targeting STAT3 during sepsis
Authors: X. Song, C.T. Wang and X.H. Geng
Sepsis is a major cause of morbidity and mortality in critically ill patients. The sepsis syndrome results from a dysregulated inflammatory response to infection that leads to multiple-organ failure, but the underlying mechanisms remain poorly understood. More and more reports show that microRNAs (miRNAs) play an important role in sepsis. In the progressi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.37
- DOI:
- 10.4238/2015.October.28.37
Genetic diversity of Setipinna taty (Engraulidae) populations from the China Sea based on mitochondrial DNA control region sequences
Authors: H.Y. Li, T.J. Xu, Y.Z. Cheng, D.Q. Sun and R.X. Wang
The genetic diversity of Setipinna taty, which is commercially fished in the China Sea, was studied based on mitochondrial DNA control region sequences. PCR was used to amplify the control region fragment in 100 individuals of S. taty collected from Weihai (WH), Yantai (YT), Zhoushan (ZS), Xiangshan (XS), and Ninghai (NH) in C.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.9.1
- DOI:
- 10.4238/2012.May.9.1
Genetic diversity and assessment of 23 microsatellite markers for parentage testing of Santa In�ªs hair sheep in Brazil
Authors: C.A. Souza, S.R. Paiva, C.M. McManus, H.C. Azevedo, A.S. Mariante and D. Grattapaglia
Santa Inês is the most common hair sheep breed in Brazil and probably has the highest genetic diversity among sheep breeds in this country. Successful breeding programs for Brazilian sheep breeds are not common for various reasons, including a lack of control of parentage in the flocks. We developed an allele frequency d.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.8.4
- DOI:
- 10.4238/2012.May.8.4