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Screening of polymorphisms located in the FGF20 and TMEM175 genes in North Chinese Parkinson�s disease patients
Authors: C.C. Jing, X.G. Luo, H.G. Cui, F.R. Li, P. Li, E.Z. Jiang, Y. Ren and H. Pang
Genome-wide association studies have reported numerous susceptibility loci for Parkinson’s disease (PD). However, there have been few replication studies examining these loci in northern Chinese populations. To evaluate the relationships among 3 polymorphic markers located in the fibroblast growth factor 20 and transmembrane protein 175 genes and th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.30
- DOI:
- 10.4238/2015.October.28.30
Characterization of Chinese eggplant isolates of the fungal pathogen Verticillium dahliae from different geographic origins
Authors: Z. Xu Z. Ali X. Hou H. Li J.X. Yi P.A. Abbasi
Verticillium dahliae is a fungal pathogen that causes wilt disease in a wide range of host plants. Characterization of virulence, morphological, and molecular variations among V. dahliae isolates from different geographic origins is essential for any breeding program aimed at producing plant cultivars resistant to this disease. We characterized virulence var.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.11
- DOI:
- 10.4238/2013.January.24.11
Association between angiotensin-converting enzyme insertion/deletion polymorphisms and the risk of heart disease: an updated meta-analysis
Authors: F.J. You and D.M. Shen
Insertion/deletion (I/D) polymorphisms of the gene encoding angiotensin converting enzyme (ACE) are a controversial risk factor for heart diseases (HDs). ACE I/D polymorphism has been reported to be associated with various cardiovascular diseases. However, some studies have presented conflicting results. In this study, we aim to explore the association be.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017194
- DOI:
- 10.4238/gmr.15017194
Analysis of genetic diversity in Larix gmelinii (Pinaceae) with RAPD and ISSR markers
Authors: L. Zhang H.G. Zhang X.F. Li
Dahurian larch (Larix gmelinii), a deciduous conifer, is the northernmost tree, native to eastern Siberia and nearby regions of China. We used growth traits and molecular markers to assess genetic variation in different L. gmelinii growing regions; 105 individual samples were collected from seven regions of the Qingshan Forestry Centre, Heilongjiang Province.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.12
- DOI:
- 10.4238/2013.January.24.12
Epistasis in intra- and inter-gene pool crosses of the common bean
Authors: J.C. Borel1, M.A.P. Ramalho2 and A.F.B. Abreu3
Epistasis has been shown to have an important role in the genetic control of several quantitative traits in the common bean. This study aimed to investigate the occurrence of epistasis in intra- and inter-pool gene crosses of the common bean. Four elite lines adapted to Brazilian conditions were used as parents, two from the Andean gene pool (ESAL 686; BR.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017573
- DOI:
- 10.4238/gmr.15017573
Development of microsatellite markers for the Neotropical endemic Brazilian Guanabara frog, Euparkerella brasiliensis, through 454 shotgun pyrosequencing
Authors: L.A. Fusinatto S. Lopes A. Silva-Ferreira J. Alexandrino C.F.B. Haddad C.F.D. Rocha F. Sequeira
The new-generation 454 GS-FLX Titanium pyrosequencing was used to isolate microsatellite markers for the Brazilian Guanabara frog, Euparkerella brasiliensis, an Atlantic forest endemic species. Three multiplex polymerase chain reaction sets were optimized for genotyping of 11 polymorphic (di- and tetranucleotide) microsatellite markers. Genetic diversity .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.15
- DOI:
- 10.4238/2013.January.24.15
Therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats
Authors: J.F. Huang, T. Zhan, X.L. Yu, Q.A. He, W.J. Huang, L.Z. Lin,Y.T. Du and Y.T. Pan
The aim of this study was to explore the therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats. Rats were fed high-fat fodder to establish a rat fatty liver model, and were then fed different concentrations of Pleurotus eryngii cellulose for six weeks. Lipitor was used as a positive control. Measured levels of alanine amino.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017805
- DOI:
- 10.4238/gmr.15017805
Characterization of polymorphic microsatellite markers for the Neotropical leaf-frog Phyllomedusa burmeisteri and cross-species amplification
Authors: T.O. Brunes M.S. van de Vliet S. Lopes J. Alexandrino C.F.B. Haddad F. Sequeira
Twelve polymorphic tetranucleotide microsatellite loci were isolated and characterized for the leaf-frog Phyllomedusa burmeisteri, an endemic species of the Brazilian Atlantic forest. These loci were screened in 25 individuals from two populations of the Minas Gerais State (Carangola and Juiz de Fora). The number of alleles per locus ranged from 3 to 16 (.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.30.10
- DOI:
- 10.4238/2013.January.30.10
Snap bean recommendation based on different methods of phenotypic stability
Authors: C.D. Marinho G.A. Gravina L.C. Ara�ºjo S.N.C. Almeida A.T. Amaral J�ºnior R.F. Daher L.S.A. Gon�§alves
In order to recommend the best strains of snap beans from the Universidade Estadual do Norte Fluminense (UENF) breeding program, different methods of analysis of phenotypic stability were adopted to evaluate the performance of 14 lines (F9 and F10) of indeterminate growth habit, which were compared with 3 controls, namely, 2 commercial varieties (Feltrin .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.30.11
- DOI:
- 10.4238/2013.January.30.11
Gene silencing during development ofin vitro-produced female bovine embryos
Authors: G.K.F. Merighe, F.H. Biase, W.K.F. Santos-Biase, M.S. Miranda,T.H.C. de Bem, Y.F. Watanabe and F.V. Meirelles
In early development, female embryos (XX) produce twice the transcripts of X-linked genes compared with male embryos (XY). During the course of development, inactivation of the X chromosome equilibrates gene dosage, making the development of female embryos viable. Moreover, the biotechnologies used for producing embr.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr638
- DOI:
- 10.4238/vol8-3gmr638