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Plant Genetics   Review Article

Fusarium wilt’s pathogenic studies and disease management: A review

Authors: Ch. Muhammad Rafiq, Muhammad Tariq Mahmood, Mushtaq Ahmad, Imtiaz Ali, Sadia Kaukab, Muhammad Shafiq, Muhammad Saleem, Umer Iqbal

Fusarium wilt caused by Fusarium oxysporum f. sp. ciceris is one of the most important fungal diseases of chickpea limiting its productivity in almost all chickpea growing countries across the world. F. oxysporum is soil borne and root inhabiting in nature which may survives in soil for longer period (up to six years). Pathogen undergoes.. Read More»

Genet. Mol. Res. 19(1):
Plant Genetics   Research Article

Genetic studies for yield and related traits in micro and macrosperma exotic lentil genotypes

Authors: Ch. Muhammad Rafiq, Sadia Kaukab, Aqsa Tahir, Masood Qadir, Busharat Hussain, Shakeel Ahmad Anwar, Muhammad Tariq Mahmood, Ali Aziz, Amir Hameed and Khalid Mehmood Mughal

With respect to seed size lentil (Lens culinaris Medikus) species usually are distributed into two main groups namely Microsperma (<2.5 g/100-seeds) with small rounded seeds and Macrosperma (>2.5 g/100-seeds) with larger and more flattened seeds. The seeds/pod and pods/plant will decrease as the seed size increases that adversely affect the.. Read More»

Genet. Mol. Res. 19(1):
Animal Genetics   Research Article

Uncoupling Proteins and Cardiac Apoptosis in High Fat Diet-Fed Male Rats

Authors: K. Alsolami, Z. Alrefaie

This study aimed to assess impact of high fat diet (HFD) on cardiac apoptosis, and cardiac uncoupling proteins (UCPs) 2&3 expression. Twenty rats were fed either (45%) or (10%) fat diet for 6 months, then cardiac tissue expression of BAX, Bcl2, Fas, Fas-L (markers for apoptotic pathways) and UCP 2&3 were assessed. Results revealed enhancement of i.. Read More»

Genet. Mol. Res. 19(1):
Human Genetics   Research Article

Asp299Gly polymorphism in TLR4 gene in patients with colorectal cancer

Authors: S. M. Shoeib, W. S. Mohamed, H. M. Nagy

Background: Toll-like receptors play important roles in innate and adaptive immunity and polymorphisms within TLR-4 as Asp299Gly are reported to be associated with certain digestive cancers e.g. colorectal carcinoma. Aim: Investigate the association between Asp299Gly polymorphism and the risk of colorectal cancer .. Read More»

Genet. Mol. Res. 18(1):
Human Genetics   Research Article

Electroporation induced membrane permeability changes at the ionic level

Authors: Sadasivam Pachamuthu, Zubin A Zaheer, Bhuvaneshwari Sampath, Dharani Muralidharan, Rajaprabu Ramachandran and Kavitha Sankaranarayanan

Background/Aim: Electrochemotherapy is an innovative method for the localized treatment of cutaneous and subcutaneous metastatic cancers. The aim of the study is to assess the changes at the plasma membrane and its recovery time by monitoring the regulated passage of ions through specific ion channels as measured by electrophysiology. Materials an.. Read More»

Genet. Mol. Res. 18(3):
Plant Genetics   Research Article

Behavior of soybean genotypes in three locations in the Triângulo Mineiro

Authors: R.M.G. Diniz, O.T. Hamawaki, A.P.O. Nogueira, C.O. Silva, R.L. Hamawaki, C.D.L. Hamawaki, F.C. Juliatti, S.L.A. Filho

Soy is an important legume for global economy. The objectives of this study were evaluated soybean genotypes in different growing environments as for their agronomic characters and resistance to leaf spots, and determine the adaptability and phenotypic stability of materials in relation to the place of cultivation. Experiments were conducted in the cities.. Read More»

Genet. Mol. Res. 18(3):
Microbial Genetics   Research Article

Differential expression of genes associated with low-level vancomycin resistance in Staphylococcus aureus

Authors: Auttawit Sirichoat, Viraphong Lulitanond, Sujintana Wongthong, Aroonwadee Chanawong, Ratree Tavichakorntrakool and Aroonlug Lulitanond

Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and vancomycin-intermediate S. aureus (VISA) have been associated with treatment failure, and hVISA cannot be detected by routine disc diffusion test. Currently, there is no specific genetic marker for detection of these strains. The aim of the current study was to inves.. Read More»

Genet. Mol. Res. 18(2):
Animal Genetics   Research Article

Development and characterization of microsatellite molecular markers for the eye mask frog Batrachyla taeniata (Girard, 1855)

Authors: Ingrid Cisternas-Medina, Juan Carlos Ortiz and Sandra Ferrada-Fuentes

Batrachyla taeniata (Batrachylidae) is a small frog from Chile and Argentina with a distributional range that spans more than 1500 km. However, their populations are threatened due to the change in land use, deforestation, and human settlements. Through massive sequencing runs in ION Torrent PGM, was built DNA fragment library, from which we fina.. Read More»

Genet. Mol. Res. 18(2):
Medical Genetics   Research Article

Expression of HCN and sodium channels in murine model of Type I diabetes

Authors: Anantha Maharasi Rama Krishnan and Kavitha Sankaranarayanan

Pancreatic apoptosis is an important event in the pathogenesis of Type 1 Diabetes. It is characterized by secretion and binding of inflammatory cytokines to the pancreatic islets, that activate downstream signaling mechanism. These signaling mechanisms finally increase intracellular calcium level and that lead to the activation of apoptotic pathways. Ion .. Read More»

Genet. Mol. Res. 18(2):
Plant Genetics   Research Article

Dynamism of the breeding program for irrigated rice in Southeast Brazil

Authors: A.C. Silva J�ºnior, V.Q. Carneiro, I.G. Santos, W.G Costa, R.D.S. Rosado, C.D. Cruz and P.C. Soares

The estimation of the genotypic replacement rate is aimed at evaluating the performance of breeding programs. Thus, the objective of this study was to evaluate the dynamics of the genetic improvement program of flooded rice, developed in Minas Gerais, during the period from 1993 to 2016. We evaluated 210 lines in three environments between 1993 and 2016, .. Read More»

Genet. Mol. Res. 19(5):