Table of Contents | Genet. Mol. Res.2017(1)
Inhibition of invasion and migration of prostate cancer cells by miRNA-509-5p via targeting MDM2
Authors: X.M. Tian, Y.Z. Luo, P. He, J. Li, Z.W. Ma and Y. An
Prostate cancer is a common malignancy of the male reproductive-urinary system. MDM2 is an oncogene, whose expression can be regulated by microRNA (miRNA). The present study investigated the expression and correlation of miRNA-509-5p and MDM2 to determine the mechanism of their function in invasion and migration of prostate ca.. Read More»
Genet. Mol. Res. 16(1): gmr16019195
DOI: 10.4238/gmr16019195
A large-scale analysis study on the clinical and viral characteristics of hepatitis B infection with concurrence of hepatitis B surface or E antigens and their corresponding antibodies
Authors: Y. Xiang, P. Chen, J.R Xia and L.P. Zhang
Concurrent detection of hepatitis B surface antigen (HBsAg) and anti-HBs antibody or hepatitis B surface E antigen (HBeAg) and anti-HBe antibody in patients with chronic hepatitis B (CHB) infection is well established. However, the clinical implications of these proteins remain largely unknown. In this study, demographic, clin.. Read More»
Genet. Mol. Res. 16(1): gmr16019102
DOI: 10.4238/gmr16019102
Identification of lipopeptides produced by Bacillus subtilis Czk1 isolated from the aerial roots of rubber trees
Authors: C.P. He, L.Y. Fan, W.H. Wu, Y.Q. Liang, R. Li, W. Tang, X.L. Zheng, Y.N. Xiao, Z.X. Liu and F.C. Zheng
We obtained a strain of Bacillus subtilis, which we named Czk1, from the aerial roots of rubber trees. This bacterial isolate exhibits strong antagonistic activity against Ganoderma pseudoferreum, Phellinus noxius, Helicobasidium compactum, Rigidoporus lignosus, Sphaerostilbe repens, and Colletotrichum gloeosporioides. Our ear.. Read More»
Genet. Mol. Res. 16(1): gmr16018710
DOI: 10.4238/gmr16018710
Polymorphisms in interleukin-6 and interleukin-10 may be associated with risk of preeclampsia
Authors: D.M. Fan, Y. Wang, X.L. Liu, A. Zhang and Q. Xu
Preeclampsia is a common condition unique to pregnant women. Previous studies have suggested that several cytokines may contribute to defective placental invasion and endothelial damage in this condition. We investigated the influence of four single nucleotide polymorphisms (SNPs) in the promoters of IL-6 (-572G/C, -597G/A, an.. Read More»
Genet. Mol. Res. 16(1): gmr16018588
DOI: 10.4238/gmr16018588
C3435T polymorphism of the MDR1 gene is not associated with blood levels of hypothalamus-pituitary-adrenal axis hormones in healthy male subjects
Authors: A. Suzuki, Y. Matsumoto, T. Shirata, K. Goto, M. Enokido, K. Otani
In vitro studies have shown that multidrug resistance protein 1 (MDR1) has an affinity for cortisol; however, in vivo association studies on the relationship between MDR1 gene polymorphisms and blood cortisol levels have produced inconsistent results. Therefore, we examined the effects of the C3435T polymorphism of the MDR1 ge.. Read More»
Genet. Mol. Res. 16(1): gmr16019447
DOI: 10.4238/gmr16019447
Digital expression analysis of the genes associated with salinity resistance after overexpression of a stress-responsive small GTP-binding RabG protein in peanut
Authors: J.M. Sui, G. Li, G.X. Chen, M.Y. Yu, S.T. Ding, J.S. Wang and L.X. Qiao
The Rab protein family is the largest family of the small GTP-binding proteins. Among them, the RabG genes are known to be responsive to abiotic stresses, but the molecular mechanisms of the stress responses mediated by RabG genes in plants is poorly understood. To investigate the molecular mechanism of AhRabG gene in peanut, .. Read More»
Genet. Mol. Res. 16(1): gmr16019432
DOI: 10.4238/gmr16019432
Microbial diversity in raw milk and traditional fermented dairy products (Hurood cheese and Jueke) from Inner Mongolia, China
Authors: M.L. Gao, H.M. Hou, X.X. Teng, Y.L. Zhu, H.S. Hao and G.L. Zhang
Hurood cheese (HC) and Jueke (Jk) are 2 traditional fermented dairy products produced from raw milk (RM) in the Inner Mongolia region of China. They have a long history of production and consumption. The microbial compositions of RM, HC, and Jk vary greatly, and are influenced by their geographical origins and unique processin.. Read More»
Genet. Mol. Res. 16(1): gmr16019451
DOI: 10.4238/gmr16019451
Changes on microsatellites of expressed sequence tag of sugarcane (Saccharum spp) during vegetative propagation
Authors: R. Augusto, R.C. Maranho, C.A. Mangolin, J.C. Bespalhok Filho and M.F.P.S. Machado
The reduction in sugarcane productivity in subsequent cutting stages may be related to a gradual decrease of the allele number and mean observed heterozygosity (HO) in the sugarcane ratoon. This hypothesis was tested assessing the number of alleles and HO values in 10 expressed sequence tag microsatellites (Est-SSR loci) of th.. Read More»
Genet. Mol. Res. 16(1): gmr16019519
DOI: 10.4238/gmr16019519