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Animal Genetics   Research Article
Single cell transcriptome profiling revealed differences in gene expression during oocyte maturation in Haimen white goats

Authors: X.Y. Yin, G.H. Cheng, H.Y. Guo, Q. Wang, Y.J. Li and H. Zhang

Juvenile in vitro embryo transfer is an important animal reproductive technology that can shorten the generation interval of livestock, explore the reproductive potential of dams with excellent genetic traits, accelerate genetic progress and production efficiency of the herd, and provide a wealth of genetic resources for lives.. Read More»

Genet. Mol. Res. 16(1): gmr16019564

DOI: 10.4238/gmr16019564

Animal Genetics   Research Article
Comparison between different selection indices in energy cane breeding

Authors: A.A.C. de Azeredo, L.L. Bhering, B.P. Brasileiro, C.D. Cruz,L.C.I. Silveira, R.A. Oliveira, J.C. Bespalhok Filho, E. Daros

Sugarcane breeding programs have been adapting to a new market demand: aside from high sucrose yield per hectare, the sector needs new cultivars with higher fiber percentages. The selection of sugarcane clones based on phenotype alone is a complex task. The selected clones should display high performance in a series of yield- .. Read More»

Genet. Mol. Res. 16(1): gmr16019535

DOI: 10.4238/gmr16019535

Human Genetics   Research Article
Red Sindhi cattle in Brazil: population structure and distribution

Authors: J.C.C. Panetto, M.V.G.B. Silva, R.M.H. Leite, M.A. Machado,F.A.T. Bruneli, D.R.L. Reis, M.G.C.D. Peixoto, R.S. Verneque

The Red Sindhi cattle breed was imported to Brazil in small numbers. Nowadays, the herds of this breed are distributed in the Northeast, Southeast and Midwest regions of the country. In this study, DNA samples of animals originating from 15 herds in the Northeast and Southeast regions have been analyzed to obtain the ancestry .. Read More»

Genet. Mol. Res. 16(1): gmr16019501

DOI: 10.4238/gmr16019501

Human Genetics   Research Article
A clinical study of bone mesenchymal stem cells for the treatment of hepatic fibrosis induced by hepatolenticular degeneration

Authors: D. Zhang

The efficacy of bone marrow mesenchymal stem cell (BMSC) on liver fibrosis in animal has been proven, but a few studies have been made in human body and few such researches in China. This study was designed to investigate the effect of BMSC treatment on hepatic fibrosis induced by hepatolenticular degeneration and the influenc.. Read More»

Genet. Mol. Res. 16(1): gmr16019352

DOI: 10.4238/gmr16019352

Human Genetics   Research Article
Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine �²-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes

Authors: F.M. Amaral, A.L. Miranda-Vilela, G.S. Lordelo, I.F. Ribeiro, M.B. Daldegan and C.K. Grisolia

High plasma homocysteine (Hcy) âÂ?Â?âÂ?Â?levels may be responsible for vaso-occlusive episodes and may have acquired and/or genetic causes. This cross-sectional study aimed to investigate the role of methylenetetrahydrofolate reductase (MTHFR; C677T; A1298C) and cystathionine-β-synthase (CBS; T833C/844ins68, G919A) poly.. Read More»

Genet. Mol. Res. 16(1): gmr16019374

DOI: 10.4238/gmr16019374

Plant Genetics   Research Article
Molecular marker-based genetic diversity analysis of scantly studied Brazilian accessions of a medicinal plant, Morinda citrifolia L. (noni)

Authors: P.N. Bordallo, A.M.R. Monteiro, J.A. Sousa and F.A.S. Arag�£o

Morinda citrifolia L., commonly known as noni, has been used for the treatment of various diseases for over two centuries. It was introduced and widely disseminated in Brazil because of its high market value and ease of adaptation to the soil and climatic conditions of the country. The aim of this study was to estimate the gen.. Read More»

Genet. Mol. Res. 16(1): gmr16019531

DOI: 10.4238/gmr16019531

Human Genetics   Research Article
Inhibition of miR-660-5p expression suppresses tumor development and metastasis in human breast cancer

Authors: Y. Shen, Y.F. Ye, L.W. Ruan, L. Bao, M.W. Wu and Y. Zhou

Breast cancer, which derives from the epithelium of the mammary glands, is one of the most common cancers diagnosed in women globally. To date, the authors of many studies have reported that the deregulation of microRNAs (miRNAs) plays a crucial role in the occurrence, development, and metastasis of tumors. Here, we discovered.. Read More»

Genet. Mol. Res. 16(1): gmr16019479

DOI: 10.4238/gmr16019479

Plant Genetics   Research Article
Identification of Magnolia wufengensis (Magnoliaceae) cultivars using phenotypic traits, SSR and SRAP markers: insights into breeding and conservation

Authors: L. Wang, A.H. Xiao, L.Y. Ma, F.J. Chen, Z.Y. Sang and J. Duan

A combination of phenotypic characterization and molecular markers may provide reliable information on new plant varieties and elucidate the conservation status of rare species. Five newly developed Magnolia wufengensis cultivars, an endangered plant species endemic to Hubei Province, China, possess more distinctive phenotypes.. Read More»

Genet. Mol. Res. 16(1): gmr16019473

DOI: 10.4238/gmr16019473