Table of Contents | Genet. Mol. Res.2016(1)
5-Fluorouracil induces apoptosis of colorectal cancer cells
Authors: J.T. Zhang1, W.L. Zhou2, C. He3, T. Liu1, C.Y. Li1 and L. Wang1
5-Fluorouracil (5-FU) is widely used in chemotherapy for treatment of colorectal cancer. Leucine-rich repeat-containing G protein-coupled receptor (LGR) is known to participate in the occurrence and development of breast cancer by regulating the rebirth of tumor vessels. This study aimed to explore the proliferation and apoptosis of HCT116 colorectal canc.. Read More»
Genet. Mol. Res. 15(1): gmr.15017326
DOI: 10.4238/gmr.15017326
Comparative evaluation of total RNA extraction methods in Theobroma cacao using shoot apical meristems
Authors: D.V. Silva1, S.M.J. Branco1, I.S.A. Holanda2, S. Royaert3, J.C. Motamayor4,J.P. Marelli4 and R.X. Corr�ªa5
Theobroma cacao is a species of great economic importance with its beans used for chocolate production. The tree has been a target of various molecular studies. It contains many polyphenols, which complicate the extraction of nucleic acids with the extraction protocols requiring a large amount of plant material. These issues, therefore, necessitate the op.. Read More»
Genet. Mol. Res. 15(1): gmr.15017364
DOI: 10.4238/gmr.15017364
Vasculogenic mimicry and hypoxia-inducible factor-1�± expression in cervical squamous cell carcinoma
Authors: T.J. Zhou1, X.H. Huang1, L. Gong1 and L. Xiang2
In this study, the existence of vasculogenic mimicry (VM) in cervical squamous cell carcinoma was investigated. To this end, the relationship between hypoxia-inducible factor 1α (HIF-1α) and the development, infiltration, and metastasis of cervical squamous cell carcinoma was studied. Between January 2010 and December 2010, 67 human cervical s.. Read More»
Genet. Mol. Res. 15(1): gmr.15017396
DOI: 10.4238/gmr.15017396
CsSAD: a fatty acid desaturase gene involved in abiotic resistance in Camellia sinensis (L.)
Authors: Z.T. Ding1,2*, J.Z. Shen1,2*, L.L. Pan1,2, Y.U. Wang1,2, Y.S. Li3, Y. Wang4 andH.W. Sun5
Tea (Camellia sinensis L.) is a thermophilic evergreen woody plant that has poor cold tolerance. The SAD gene plays a key role in regulating fatty acid synthesis and membrane lipid fluidity in response to temperature change. In this study, full-length SAD cDNA was cloned from tea leaves using rapid amplification of cDNA ends and polymerase chain reaction .. Read More»
Genet. Mol. Res. 15(1): gmr.15017512
DOI: 10.4238/gmr.15017512
Differential expression of FUT1 and FUT2 in Large White, Meishan, and Sutai porcine breeds
Authors: R.W. Xia1, W.Y. Qin1, L.N. Gan1, J. Wang1, S.L. Wu1,2 and W.B. Bao1,2
To assess the relationship between the expression of a(1,2)-fucosyltransferase (FUT1 and FUT2) genes and resistance to Escherichia coli F18 in weaned pigs, FUT1 and FUT2 expression levels in Large White, Meishan, and Sutai pigs (with resistance to E. coli F18) were determined using real-time PCR. The results revealed that FUT1 and FUT2 expression levels w.. Read More»
Genet. Mol. Res. 15(1): gmr.15017613
DOI: 10.4238/gmr.15017613
Common genetic risk factors of venous thromboembolism in Western and Asian populations
Authors: S.S. Huang1*, Y. Liu2*, Z.C. Jing3, X.J. Wang3 and Y.M. Mao1
Venous thromboembolism (VTE) is a multifactorial disorder involving both acquired and genetic risk factors. The common genetic factors in Western populations have been studied and reported for several decades, while studies on Asian populations are relatively scarce. Evidence suggests that the prevalence and genetic risk factors of VTE vary significantly .. Read More»
Genet. Mol. Res. 15(1): gmr.15017644
DOI: 10.4238/gmr.15017644
Effects of grafting on key photosynthetic enzymes and gene expression in the citrus cultivar Huangguogan
Authors: L. Liao1, S.Y. Cao1, Y. Rong1 and Z.H. Wang1,2
Grafting influences scion photosynthetic capacity and fruit quality. Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), which strongly affects photosynthetic rate, and Rubisco activase (RCA), which regulates Rubisco activity, are two key photosynthetic enzymes. However, little information is available regarding the effect of grafting on the concen.. Read More»
Genet. Mol. Res. 15(1): gmr.15017690
DOI: 10.4238/gmr.15017690
Expression of microRNA-210 in tissue and serum of renal carcinoma patients and its effect on renal carcinoma cell proliferation, apoptosis, and invasion
Authors: T.Y. Liu1, H. Zhang2, S.M. Du3, J. Li1 and X.H. Wen1
This study investigated the expression of microRNA-210 (miR-210) in tissue and serum of renal carcinoma patients and its effect on renal carcinoma cell proliferation, apoptosis, and invasion. Thirty-two renal carcinoma patients in our hospital were selected as the study group and 32 people receiving a physical examination were selected as the control grou.. Read More»
Genet. Mol. Res. 15(1): gmr.15017746
DOI: 10.4238/gmr.15017746