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Human Genetics   Research Article
Corrigendum: Association between TAP1 gene polymorphisms and alopecia areata in a Korean population - Genet. Mol. Res. 14 (4): 18820-18827

Authors: H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. Lee3, S. Lee4, I.H. Cho5, J.T. Kwon1 and H.J. Kim1,6

H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. Lee3, S. Lee4, I.H. Cho5, J.T. Kwon1 and H.J. Kim1,6 5Department of Convergence Medical Science, Brain Korea 21 Plus Program, and Institute of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. .. Read More»

Genet. Mol. Res. 15(1): gmr.150170751

DOI: 10.4238/gmr.150170751

Plant Genetics   Research Article
Antimicrobial potential of actinobacteria isolated from the rhizosphere of the Caatinga biome plant Caesalpinia pyramidalis Tul.

Authors: G.R. Silva-Lacerda, R.C.F. Santana, M.C.V. Vicalvi-Costa, E.G. Solid�´nio, K.X.F.R. Sena, G.M.S. Lima and J.M. Ara�ºjo

Actinobacteria are known to produce various secondary metabolites having antibiotic effects. This study assessed the antimicrobial potential of actinobacteria isolated from the rhizosphere of Caesalpinia pyramidalis Tul. from the Caatinga biome. Sixty-eight actinobacteria isolates were evaluated for antimicrobial activity against different microorganisms .. Read More»

Genet. Mol. Res. 15(1): gmr.15017488

DOI: 10.4238/gmr.15017488

Plant Genetics   Research Article
Validation of EST-derived microsatellite markers for two Cerrado-endemic Campomanesia (Myrtaceae) species

Authors: E.A.G.C. Miranda1, C.R.D. Boaventura-Novaes2, R.S. Braga1, E.F. Reis3,J.F.N. Pinto3 and M.P.C. Telles1

We assessed the transferability of 120 EST-derived Eucalyptus microsatellite primers to Campomanesia adamantium and C. pubescens. Both species are berry trees native to the Brazilian Cerrado, and population genetic information is poor. Twelve markers were used to analyze the genetic variability of four sampled populations. Regarding DNA extraction, we sam.. Read More»

Genet. Mol. Res. 15(1): gmr.15017658

DOI: 10.4238/gmr.15017658

Human Genetics   Research Article
rs3918242 MMP9 gene polymorphism is associated with myocardial infarction in Mexican patients

Authors: J.M. Rodr�­guez-P�©rez1*, G. Vargas-Alarc�³n1*, R. Posadas-S�¡nchez2,T.X. Zagal-Jim�©nez1, R. Ort�­z-Alarc�³n1, B. Valente-Acosta1, C. Tovilla-Z�¡rate3, C. Nostroza-Hern�¡ndez1, O. P�©rez-M�©ndez1 and N. P�©rez-Hern�¡ndez1,4

Several studies have demonstrated that matrix metalloproteinases (MMPs) play a major role in atherosclerotic plaque disruption and lead to myocardial infarction (MI). We investigated the association between the MMP1 -1607 1G/2G (rs1799750), MMP3 -1612 5A/6A (rs3025058), and MMP9 -1562 C/T (rs3918242) polymorphisms and the risk of developing MI in a Mexica.. Read More»

Genet. Mol. Res. 15(1): gmr.15017776

DOI: 10.4238/gmr.15017776

Animal Genetics   Research Article
Desmoglein 4 diversity and correlation analysis with coat color in goat

Authors: G.X. E1, Y.J. Zhao1, Y.H. Ma2, G.L. Cao3, J.N. He4, R.S. Na1, Z.Q. Zhao1,C.D. Jiang1, J.H. Zhang1, S. Arlvd5, L.P. Chen1, X.Y. Qiu1, W. Hu1 and Y.F. Huang1

Desmoglein 4 (DSG4) has an important role in the development of wool traits in domestic animals. The full-length DSG4 gene, which contains 3918 bp, a complete open-reading-frame, and encodes a 1040-amino acid protein, was amplified from Liaoning cashmere goat. The sequence was compared with that of DSG4 from other animals and the results show that the DSG.. Read More»

Genet. Mol. Res. 15(1): gmr.15017814

DOI: 10.4238/gmr.15017814

Human Genetics   Research Article
Effects of probucol on cultured human umbilical vein endothelial cells injured by hypoxia/reoxygenation

Authors: Y.L. Chai, J.Z. Xu, Y.L. Zhang and G.T. Sheng

There is increasing evidence suggesting that endoplasmic reticulum stress (ERS) plays an important role in the initiation and development of atherosclerosis. This study was designed to examine the effect of probucol on cultured human umbilical vein endothelial cells (HUVECs) injured by hypoxia/reoxygenation (H/R) and the potential mechanisms involving ERS.. Read More»

Genet. Mol. Res. 15(1): gmr.15016752

DOI: 10.4238/gmr.15016752

Human Genetics   Research Article
Effect of ST2825 on the proliferation and apoptosis of human hepatocellular carcinoma cells

Authors: Y. Deng, J. Sun and L.D. Zhang

The purpose of this study was to investigate the effect of ST2825, an inhibitor of myeloid differentiation factor 88 (MyD88), on the proliferation and apoptosis of human hepatocellular carcinoma (HCC) cells as well as the potential mechanism and clinical significance of ST2825 in the treatment of HCC. Immunohistochemical staining with an MyD88 antibody wa.. Read More»

Genet. Mol. Res. 15(1): gmr.15016826

DOI: 10.4238/gmr.15016826

Human Genetics   Research Article
Association of N-acetyltransferase-2 polymorphism with an increased risk of coronary heart disease in a Chinese population

Authors: J.D. Sun, H. Yuan, H.Q. Hu and H.M. Yu

We investigated the possible correlations between N-acetyltransferase-2 (NAT2) gene polymorphisms and the risk of coronary heart disease (CHD). CHD patients (113) and healthy controls (118) were enrolled from the First People’s Hospital of Yuhang between January 2013 and June 2014. The patients were divided into mild CHD (N = 72) and severe CHD (N =.. Read More»

Genet. Mol. Res. 15(1): gmr.15016954

DOI: 10.4238/gmr.15016954