
Authors: H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. Lee3, S. Lee4, I.H. Cho5, J.T. Kwon1 and H.J. Kim1,6
H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. Lee3, S. Lee4, I.H. Cho5, J.T. Kwon1 and H.J. Kim1,6 5Department of Convergence Medical Science, Brain Korea 21 Plus Program, and Institute of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. .. Read More»
Genet. Mol. Res. 15(1): gmr.150170751
DOI: 10.4238/gmr.150170751
Authors: G.R. Silva-Lacerda, R.C.F. Santana, M.C.V. Vicalvi-Costa, E.G. Solid�´nio, K.X.F.R. Sena, G.M.S. Lima and J.M. Ara�ºjo
Actinobacteria are known to produce various secondary metabolites having antibiotic effects. This study assessed the antimicrobial potential of actinobacteria isolated from the rhizosphere of Caesalpinia pyramidalis Tul. from the Caatinga biome. Sixty-eight actinobacteria isolates were evaluated for antimicrobial activity against different microorganisms .. Read More»
Genet. Mol. Res. 15(1): gmr.15017488
DOI: 10.4238/gmr.15017488
Authors: E.A.G.C. Miranda1, C.R.D. Boaventura-Novaes2, R.S. Braga1, E.F. Reis3,J.F.N. Pinto3 and M.P.C. Telles1
We assessed the transferability of 120 EST-derived Eucalyptus microsatellite primers to Campomanesia adamantium and C. pubescens. Both species are berry trees native to the Brazilian Cerrado, and population genetic information is poor. Twelve markers were used to analyze the genetic variability of four sampled populations. Regarding DNA extraction, we sam.. Read More»
Genet. Mol. Res. 15(1): gmr.15017658
DOI: 10.4238/gmr.15017658
Authors: J.M. RodrÃ?Âguez-PÃ?©rez1*, G. Vargas-AlarcÃ?³n1*, R. Posadas-SÃ?¡nchez2,T.X. Zagal-JimÃ?©nez1, R. OrtÃ?Âz-AlarcÃ?³n1, B. Valente-Acosta1, C. Tovilla-ZÃ?¡rate3, C. Nostroza-HernÃ?¡ndez1, O. PÃ?©rez-MÃ?©ndez1 and N. PÃ?©rez-HernÃ?¡ndez1,4
Several studies have demonstrated that matrix metalloproteinases (MMPs) play a major role in atherosclerotic plaque disruption and lead to myocardial infarction (MI). We investigated the association between the MMP1 -1607 1G/2G (rs1799750), MMP3 -1612 5A/6A (rs3025058), and MMP9 -1562 C/T (rs3918242) polymorphisms and the risk of developing MI in a Mexica.. Read More»
Genet. Mol. Res. 15(1): gmr.15017776
DOI: 10.4238/gmr.15017776
Authors: G.X. E1, Y.J. Zhao1, Y.H. Ma2, G.L. Cao3, J.N. He4, R.S. Na1, Z.Q. Zhao1,C.D. Jiang1, J.H. Zhang1, S. Arlvd5, L.P. Chen1, X.Y. Qiu1, W. Hu1 and Y.F. Huang1
Desmoglein 4 (DSG4) has an important role in the development of wool traits in domestic animals. The full-length DSG4 gene, which contains 3918 bp, a complete open-reading-frame, and encodes a 1040-amino acid protein, was amplified from Liaoning cashmere goat. The sequence was compared with that of DSG4 from other animals and the results show that the DSG.. Read More»
Genet. Mol. Res. 15(1): gmr.15017814
DOI: 10.4238/gmr.15017814
Authors: Y.L. Chai, J.Z. Xu, Y.L. Zhang and G.T. Sheng
There is increasing evidence suggesting that endoplasmic reticulum stress (ERS) plays an important role in the initiation and development of atherosclerosis. This study was designed to examine the effect of probucol on cultured human umbilical vein endothelial cells (HUVECs) injured by hypoxia/reoxygenation (H/R) and the potential mechanisms involving ERS.. Read More»
Genet. Mol. Res. 15(1): gmr.15016752
DOI: 10.4238/gmr.15016752
Authors: Y. Deng, J. Sun and L.D. Zhang
The purpose of this study was to investigate the effect of ST2825, an inhibitor of myeloid differentiation factor 88 (MyD88), on the proliferation and apoptosis of human hepatocellular carcinoma (HCC) cells as well as the potential mechanism and clinical significance of ST2825 in the treatment of HCC. Immunohistochemical staining with an MyD88 antibody wa.. Read More»
Genet. Mol. Res. 15(1): gmr.15016826
DOI: 10.4238/gmr.15016826
Authors: J.D. Sun, H. Yuan, H.Q. Hu and H.M. Yu
We investigated the possible correlations between N-acetyltransferase-2 (NAT2) gene polymorphisms and the risk of coronary heart disease (CHD). CHD patients (113) and healthy controls (118) were enrolled from the First People’s Hospital of Yuhang between January 2013 and June 2014. The patients were divided into mild CHD (N = 72) and severe CHD (N =.. Read More»
Genet. Mol. Res. 15(1): gmr.15016954
DOI: 10.4238/gmr.15016954