Table of Contents | Genet. Mol. Res.2016(1)
Characterization of the inaA gene and expression of ice nucleation phenotype in Pantoea ananatis isolates from Maize White Spot disease
Authors: A.M. Miller1, J.E.F. Figueiredo3, G.A. Linde4, N.B. Colauto4and L.D. Paccola-Meirelles1,2,4
Maize White Spot (MWS), a foliar disease caused by Pantoea ananatis, could cause up to 60% yield loss. Some strains of P. ananatis harboring the ice nucleation gene inaA catalyze the formation of ice nuclei, causing tissue damage at temperatures slightly below freezing. Little is known about the relationship between the presence of the ina gene in this ma.. Read More»
Genet. Mol. Res. 15(1): 0.4238/gmr.15017863
DOI: 0.4238/gmr.15017863
Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway
Authors: Z.G. Peng1, D.C. Liu2, Y.B. Yao1, X.L. Feng3, X. Huang1, Y.L. Tang1, J. Yang1 and X.X. Wang1
Paclitaxel (PTX) is a mitotic inhibitor widely used in chemotherapy for many types of cancers, including solid tumors and hematological malignancies. However, the molecular basis of the anti-proliferation activity of PTX is not fully understood. In this paper, we focused on the role of c-Jun N-terminal kinase (JNK) pathways in PTX-induced apoptosis and pr.. Read More»
Genet. Mol. Res. 15(1): gmr.15013904
DOI: 10.4238/gmr.15013904
Identification of polymorphisms and transcriptional activity of the proto-oncogene KIT located on both autosomal and B chromosomes of the Chinese raccoon dog
Authors: Y.M. Li1, Y. Zhang1, W.J. Zhu1, S.Q. Yan1 and J.H. Sun2
B chromosomes are dispensable and co-exist with autosomal and sex chromosomes. The karyotype of the Chinese raccoon dog (Nyctereutes procyonoides procyonoides) comprises 0-4 B chromosomes. The proto-oncogene KIT is found on all B chromosomes of the Chinese raccoon dog. In the present study, partial DNA and mRNA sequences of KIT were amplified and sequence.. Read More»
Genet. Mol. Res. 15(1): gmr.15017398
DOI: 10.4238/gmr.15017398
Antisense expression of Gossypium hirsutum UDP-glucuronate decarboxylase in Arabidopsis leads to changes in cell wall components
Authors: D.M. Zhang1*, Y.X. Pan2*, Y. Zhang1, Z.K. Li1, L.Q. Wu1, H.W. Liu1, G.Y. Zhang1, X.F. Wang1 and Z.Y. Ma1
UDP-glucuronate decarboxylase (UDP-xylose synthase; UXS, EC 4.1.1.35) is an essential enzyme of the non-cellulosic polysaccharide biosynthetic pathway. In the present study, using transient expression of fluorescently labeled Gossypium hirsutum UXS (GhUXS3) protein in onion epidermal cells, we observed that this protein was distributed in the cytoplasm. T.. Read More»
Genet. Mol. Res. 15(1): gmr.15017409
DOI: 10.4238/gmr.15017409
Effects and mechanism of Tripterygium wilfordii on chronic glomerulo nephritis
Authors: W.Y. Pei1, C.H. Yang2 and X.L. Zhang3
The objective of this study was to investigate the clinical effects of Tripterygium wilfordii on chronic glomerulo nephritis (CGN) and its mechanisms. Eighty-two cases of CGN treated in our hospital were randomly divided into observation and control groups. The control group was treated with conventional western medicine, and the observation group was tre.. Read More»
Genet. Mol. Res. 15(1): gmr.15017410
DOI: 10.4238/gmr.15017410
Genotoxic potential of leaf extracts of Jatropha gossypiifolia L.
Authors: P.M. Almeida1,2, S.S. Ara�ºjo1, I.R.M.R. Santos1, M.A. Marin-Morales3,A.M. Benko-Iseppon1, A.V. Santos4, K.P. Randau4 and A.C. Brasileiro-Vidal1
Jatropha gossypiifolia L. (Euphorbiaceae) is widely used in popular medicine. However, further toxicological studies are necessary for its reliable use. The present study aimed to evaluate the cytotoxic, genotoxic, and mutagenic effects of ethanolic and aqueous leaf extracts of J. gossypiifolia, using the test system Allium cepa. In addition, the phytoche.. Read More»
Genet. Mol. Res. 15(1): 0.4238/gmr.15017415
DOI: 0.4238/gmr.15017415
Single nucleotide polymorphisms in the CNTNAP2 gene in Brazilian patients with autistic spectrum disorder
Authors: P.P. Nascimento1, A.L. Bossolani-Martins2, D.B.A. Rosan1, L.C. Mattos3,C. Brand�£o-Mattos3 and A.C. Fett-Conte3
The role of some genes and their single nucleotide polymorphisms (SNPs) as genetic contributors of complex diseases is still a topic of much investigation. Research on genes related to autism susceptibility has been somewhat challenging, but also promising. Common genomic variants of CNTNAP2 have been associated with autism, and a range of autistic phenot.. Read More»
Genet. Mol. Res. 15(1): gmr.15017422
DOI: 10.4238/gmr.15017422
Analysis of the mitochondrial COI gene and its informative potential for evolutionary inferences in the families Coreidae and Pentatomidae (Heteroptera)
Authors: H.V. Souza1, S.R.C. Marchesin2 and M.M. Itoyama1
The mitochondrial cytochrome oxidase subunit 1 (COI) gene is one of the most popular markers used for molecular systematics. Fragments of this gene are often used to infer phylogenies, particularly the region near the 5'-end, which is used by the DNA Barcoding Consortium. With a growing number of sequences being deposited in the DNA barcoding database, th.. Read More»
Genet. Mol. Res. 15(1): 0.4238/gmr.15017428
DOI: 0.4238/gmr.15017428