Table of Contents | Genet. Mol. Res.2016(1)
PDK2 and ABCG2 genes polymorphisms are correlated with blood glucose levels and uric acid in Tibetan gout patients
Authors: Y.C. Ren1,2*, T.B. Jin1,2,4,5*, X.D. Sun6, T.T. Geng2,3*, M.X. Zhang1,2, L. Wang4,5,T. Feng2, L.L. Kang4,5 and C. Chen1,2
Previous studies have shown that the PDK2 and ABCG2 genes play important roles in many aspects of gout development in European populations. However, a detailed genotype-phenotype analysis was not performed. The aim of the present study was to investigate the potential association between variants in these two genes and metabolism-related quantitative phen.. Read More»
Genet. Mol. Res. 15(1): gmr.15017447
DOI: 10.4238/gmr.15017447
Genetic variability of XRCC1 influences the treatment outcome of gastric cancer
Authors: H.Q. Hu1, F. Wang2, X. Du2, X.Z. Zhao2, Z. Jin2 and M.X. Hou2
We aimed to investigate the role of XRCC1 codon 194 (Arg>Trp), 280 (Arg>His), and 399 (Arg>Gln) polymorphisms in response to chemotherapy and the overall survival of gastric cancer patients. A total of 172 patients were recruited for our study between January 2010 and March 2012. Genotyping of the three XRCC1 codons was carried out by restriction.. Read More»
Genet. Mol. Res. 15(1): gmr.15017452
DOI: 10.4238/gmr.15017452
Coconut genome size determined by flow cytometry: Tall versus Dwarf types
Authors: M. Freitas Neto1, T.N.S. Pereira1, I.G.C. Geronimo1, A.O.N. Azevedo1,S.R.R. Ramos2 and M.G. Pereira1
Coconuts (Cocos nucifera L.) are tropical palm trees that are classified into Tall and Dwarf types based on height, and both types are diploid (2n = 2x = 32 chromosomes). The reproduction mode is autogamous for Dwarf types and allogamous for Tall types. One hypothesis for the origin of the Dwarf coconut suggests that it is a Tall variant that resulted fro.. Read More»
Genet. Mol. Res. 15(1): gmr.15017470
DOI: 10.4238/gmr.15017470
Manipulation of components that control feeding behavior in Drosophila melanogaster increases sensitivity to amino acid starvation
Authors: J.D. Slade and B.E. Staveley
Feeding is a complex behavior that is regulated by several internal mechanisms. Neuropeptides are able to survey quantities of stored energy and inform the organism if nutrient intake is required. In addition to this homeostatic regulation, a post-feeding reward system positively reinforces feeding. Slight adjustments to either system can tilt the balance.. Read More»
Genet. Mol. Res. 15(1): gmr.15017489
DOI: 10.4238/gmr.15017489
Estrogenic effects of flavonoid components in Xiaoyao powder
Authors: J.H. Chen1, N. Zhang1, Y.Q. Wang1, J.Z. Wang1, S.X. Ji1, W.J. Dang1, S.M. Li2 and L. Feng2
The objective of this study was to evaluate the estrogenic effects and mechanisms of three flavonoid components in Xiaoyao powder: quercetin, kaempferol, and isorhamnetin. The drugs were used to treat estrogen receptor (ER)-positive human breast cancer MCF-7 cells, and proliferation was measured using the MTT method. The expression of proteins and mRNA of.. Read More»
Genet. Mol. Res. 15(1): gmr.15017500
DOI: 10.4238/gmr.15017500
Genome wide association study on early puberty in Bos indicus
Authors: A.V. Nascimento1, M.C. Matos2, L.O. Seno3, A.R.S. Romero1, J.F. Garcia4 andA.B. Grisolia1
The aim of this study was to evaluate a genome wide association study (GWAS) approach to identify single nucleotide polymorphisms (SNPs) associated with fertility traits (early puberty) in Nellore cattle (Bos indicus). Fifty-five Nellore cows were selected from a herd monitored for early puberty onset (positive pregnancy at 18 months of age). Extremes of .. Read More»
Genet. Mol. Res. 15(1): gmr.15017548
DOI: 10.4238/gmr.15017548
Key KdSOC1 gene expression profiles during plantlet morphogenesis under hormone, photoperiod, and drought treatments
Authors: C. Liu1*, C. Zhu2* and H.M. Zeng1
Kalanchoe daigremontiana utilizes plantlet formation between its zigzag leaf margins as its method of asexual reproduction. In this study, K. daigremontiana SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (KdSOC1), a key intermediate in the transition from vegetative to asexual growth, was cloned. Furthermore, its expression profiles during plantlet formation .. Read More»
Genet. Mol. Res. 15(1): gmr.15017579
DOI: 10.4238/gmr.15017579
Biometry and diversity of Arabica coffee genotypes cultivated in a high density plant system
Authors: W.N. Rodrigues, M.A. Tomaz, M.A.G. Ferr�£o, L.D. Martins, T.V. Colodetti, S.V.B. Brinate, J.F.T. Amaral, F.M. Sobreira and M.A. Apost�³lico
The present study was developed to respond to the need for an increase in crop yield in the mountain region of Caparaó (southern Espírito Santo State, Brazil), an area of traditional coffee production. This study aimed to analyze the diversity and characterize the crop yield of genotypes of Coffea arabica L. with potential for cultivation in.. Read More»
Genet. Mol. Res. 15(1): gmr.15017724
DOI: 10.4238/gmr.15017724