Table of Contents | Genet. Mol. Res.2016(1)
Molecular properties of the N-terminal extension of the fission yeast kinesin-5, Cut7
Authors: M. Edamatsu
Kinesin-5 plays an essential role in spindle formation and function, and serves as a potential target for anti-cancer drugs. The aim of this study was to elucidate the molecular properties of the N-terminal extension of the Schizosaccharomyces pombe kinesin-5, Cut7. This extension is rich in charged amino acids and predicted to be intrinsically disordered.. Read More»
Genet. Mol. Res. 15(1): gmr.15017799
DOI: 10.4238/gmr.15017799
Resistin expression in adipose tissues and its effect on glucose metabolism in rats with brain injury
Authors: R. Zhang1, Z.Y. Wang1, L.L. Zhu1, F. Wu1, D.Q. Chen1, L.F. Sun1 and Z.Q. Lu2
Resistin (RSTN) expression in subcutaneous adipose tissue, and its effect on glucose metabolism in rats with traumatic brain injury, was investigated using real-time PCR, western blots, and enzyme linked immunoassays. Our results show that the expression of RSTN mRNA (3.192 ± 0.046, 4.016 ± 0.010, 6.004 ± 0.020, 8.213 ± 0.013, .. Read More»
Genet. Mol. Res. 15(1): gmr.15017659
DOI: 10.4238/gmr.15017659
Array-CGH analysis in patients with intellectual disability and/or congenital malformations in Brazil
Authors: G.S. Vianna1, P.F.V. Medeiros2, A.F. Alves2, T.O. Silva2 and F.S. Jehee1
In several patients, intellectual disability and/or congenital malformation may be attributed to chromosomal changes. In this study, we conducted an array-CGH test of 200 patients from the Northeast of Brazil with intellectual disability and/or congenital malformation. Blood samples were collected from the proband and from their parents when possible. DNA.. Read More»
Genet. Mol. Res. 15(1): gmr.15017769
DOI: 10.4238/gmr.15017769
Isolation and molecular characterization of Leptospira borgpetersenii serovar Hardjo strain Hardjobovis in the urine of naturally infected cattle in Brazil
Authors: R.T. Chideroli1, U.P. Pereira2, D.D. Gon�§alves3, A.Y. Nakamura4, A.A. Alfieri5, A.F. Alfieri5 and J.C. Freitas1
Most epidemiologic studies on bovine leptospirosis are based on serological tests that use antibodies against several serotypes, including the serovar Hardjo, which is widespread and considered to be the most adapted to bovine hosts. However, using only serological studies is not sufficient to identify and distinguish species of leptospires. The aim of th.. Read More»
Genet. Mol. Res. 15(1): gmr.15018473
DOI: 10.4238/gmr.15018473
Study of biochemical changes in blood and various organs of Phrynops geoffroanus (Schweigger, 1812) (Testudines: Chelidae) collected in contaminated environment or exposed to benzo[a]pyrene
Authors: M.I.A. Silva, T.L. Silva and E.A. Almeida
The aquatic organisms are often exposed to a wide variety of chemicals, whose individual components are likely to produce different responses within the organisms and/or interact producing additive, synergistic or antagonistic toxic effects. Most of these substances are potentially cytotoxic, genotoxic or carcinogenic, such as polycyclic aromatic hydrocar.. Read More»
Genet. Mol. Res. 15(1): gmr.15018568
DOI: 10.4238/gmr.15018568
Estimates of genetic parameters for stayability and their associations with traits of economic interest in Gir dairy cows
Authors: R.M.O. Silva1,2, A.A. Boligon2, A.R. Fernandes3, A.E. Vercesi Filho4, L. El Faro4, H. Tonhati2, L.G. Albuquerque2 and A.B. Fraga1
The objective of the present study was to estimate genetic parameters for stayability at 60 months of age (STAY60) and its association with first lactation cumulative milk yield (P305), age at first calving (AFC), and first calving interval (FCI), in order to adopt these traits as selection criteria for longevity in Gir dairy cattle. Records for 2770 cows.. Read More»
Genet. Mol. Res. 15(1): gmr.15016958
DOI: 10.4238/gmr.15016958
Molecular identification of the traditional herbal medicines, Arisaematis Rhizoma and Pinelliae Tuber, and common adulterants via universal DNA barcode sequences
Authors: B.C. Moon, W.J. Kim, Y. Ji, Y.M. Lee, Y.M. Kang and G. Choi
Methods to identify Pinelliae Tuber and Arisaematis Rhizoma are required because of frequent reciprocal substitution between these two herbal medicines and the existence of several closely related plant materials. As a result of the morphological similarity of dried tubers, correct discrimination of authentic herbal medicines is difficult by conventional .. Read More»
Genet. Mol. Res. 15(1): gmr.15017064
DOI: 10.4238/gmr.15017064
Genetic study of skin thickness and its association with postweaning growth in Nellore cattle: estimation of the genetic parameters
Authors: A.M. Maiorano1, M.C.S. Oliveira2, J.N.S.G. Cyrillo3, L.G. Albuquerque1,R.A. Curi4 and J.A.IIV. Silva4
The objective of the present study was to estimate genetic parameters for skin thickness (ST) and postweaning weight gain (PWG550) in Nellore cattle. Records were obtained from 152,392 Nellore animals born between 2001 and 2011. ST was measured in the posterior region of the animal’s scapula with a millimeter caliper. The animals were assigned to di.. Read More»
Genet. Mol. Res. 15(1): gmr.15017124
DOI: 10.4238/gmr.15017124