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Animal Genetics   Research Article
Isolation and characterization of novel polymorphic microsatellite loci in Perinereis aibuhitensis

Authors: Y. Liu, D. Yu, Q. Wang, H. Liu, S. Guan and M. Liu

Perinereis aibuhitensis is a commercially and ecologically important intertidal worm. In this study, eight polymorphic microsatellite loci were isolated in this species for the first time, and a wild population was used to estimate the properties of these loci. The number of alleles per locus ranged from 6 to 20, and the observed and expected heterozygosi.. Read More»

Genet. Mol. Res. 15(1): gmr.15017144

DOI: 10.4238/gmr.15017144

Plant Genetics   Research Article
Population structure of rice varieties used in Turkish rice breeding programs determined using simple-sequence repeat and inter-primer binding site-retrotransposon data

Authors: G. C�¶mertpay1, F.S. Baloch2, M. Derya3, E.E. Andeden3, A. Alsaleh3, H. S�¼rek4 and H. ��zkan5

Abstract Effective breeding programs based on genetic diversity are needed to broaden the genetic basis of rice (Oryza sativa L.) in Turkey. In this study, 81 commercial varieties from seven countries were studied in order to estimate the genomic relationships among them using nine inter-primer binding site (iPBS)-retrotransposon and 17 simple-sequence r.. Read More»

Genet. Mol. Res. 15(1): gmr.15017158

DOI: 10.4238/gmr.15017158

Human Genetics   Research Article
Expression of transforming growth factor-�²1 and connective tissue growth factor in congenital biliary atresia and neonatal hepatitis liver tissue

Authors: F.B. Li1, H. Zhao1, K.R. Peng1, Z.G. Gao2, S.J. Huang2, J.F. Tou2, X.L. Shu3and W.Z. Gu4

We investigated the expression of transforming growth factor-β1 (TGF-β1) and connective tissue growth factor (CTGF) in the liver tissue of infants with congenital biliary atresia and neonatal hepatitis, as well as the relationship between the expression of the two factors and liver fibrosis. Thirty-six infants who met the cholestasis criteria we.. Read More»

Genet. Mol. Res. 15(1): gmr.15017217

DOI: 10.4238/gmr.15017217

Human Genetics   Research Article
Immunoexpression of HPV 16/18 E6 and E7 oncoproteins in high-grade cervical squamous intraepithelial lesions in HIV-positive women

Authors: L.C. Rodrigues1, N.M. de Gois Speck1, G.R. de Azevedo Focchi2, M.A. Schimidt1, R.M. Marques3 and J.C. Lascasas Ribalta1

The aim of this study was to assess the immunoexpression of human papillomavirus genotypes 16 and 18 (E6 and E7) oncoproteins in cervical high-grade squamous intraepithelial lesions (HSIL) of human immunodeficiency virus (HIV)-positive women. These results were also compared to the persistence and/or recurrence of lesions after loop electrosurgical excisi.. Read More»

Genet. Mol. Res. 15(1): gmr.15017220

DOI: 10.4238/gmr.15017220

Human Genetics   Research Article
Genetic variability of CYP3A4 in a heterogeneous Brazilian population from Maranh�£o

Authors: S.C. Moutinho Monteiro1, I.H. de Sousa1, I.K. Pereira Belfort1,J.D. Nunes1, B.A. Sousa Penha1, M. dos Santos2, I. Drumond Louro3 and I.D.C. Guerreiro da Silva4

Inter-individual variability in drug metabolism may result in adverse drug responses. Pharmacogenetic studies have shown that polymorphisms in drug metabolizing enzymes may contribute to this variability. Among these enzymes, CYP3A4 is responsible for metabolizing over 50% of the clinically used drugs. The Brazilian population is composed of people with N.. Read More»

Genet. Mol. Res. 15(1): gmr.15017275

DOI: 10.4238/gmr.15017275

Plant Genetics   Research Article
Cloning and characterization of SPL-family genes in the peanut (Arachis hypogaea L.)

Authors: M. Li1*, S.Z. Zhao1*, C.Z. Zhao1, Y. Zhang1, H. Xia1, J. Lopez-Baltazar2, S.B. Wan1 and X.J. Wang1

SQUAMOSA promoter-binding protein-like (SPL) proteins play crucial roles in plant growth, development, and responses to environmental stressors. The peanut (Arachis hypogaea L.) is a globally important oil crop. In this study, we cloned the full-length cDNA of 15 SPLs in the peanut by transcriptome sequencing and rapid amplification of cDNA ends, and anal.. Read More»

Genet. Mol. Res. 15(1): gmr.15017344

DOI: 10.4238/gmr.15017344

Plant Genetics   Research Article
Molecular characterization of patchouli (Pogostemon spp) germplasm

Authors: S.S. Sandes1, M.I. Zucchi2, J.B. Pinheiro3, M.M. Bajay3, C.E.A. Batista3,F.A. Brito1, M.F. Arrigoni-Blank1, S.V. Alvares-Carvalho1, R. Silva-Mann1 and A.F. Blank1

atchouli [Pogostemon cablin (Blanco) Benth.] is an aromatic, herbaceous plant belonging to the Lamiaceae family native to Southeast Asia. Its leaves produce an essential oil regularly used by the perfume and cosmetics industries. However, since patchouli from the Philippines and India were described and named Pogostemon patchouli, there has been a diverge.. Read More»

Genet. Mol. Res. 15(1): gmr.15017458

DOI: 10.4238/gmr.15017458

Plant Genetics   Research Article
Relationship between 5-HTTLPR polymorphism and post-stroke depression

Authors: W.Y. Guo1,4*, Z.H. Zhang2*, J.L. Mu3, D. Liu3, L. Zhao2, Z.Y. Yao4,5 and J.G. Song3

Post-stroke depression (PSD) is a mental illness characterized by subjective feelings of depression, cognitive dysfunction, and decreased interest. The serotoninergic system is involved in the pathogenesis of depressive disorders and is regulated by the serotonin transporter gene. The serotonin transporter-linked polymorphic region (5-HTTLPR) has been exa.. Read More»

Genet. Mol. Res. 15(1): gmr.15017460

DOI: 10.4238/gmr.15017460