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Human Genetics   Research Article
Polymorphisms in promoter regions of IL-6 and IL-10 genes in breast cancer: a case-control study

Authors: E.S. AlSuhaibani, N.A. Kizilbash, S. Malik, J.I. Dasti, F. Al Beladi and N. El-Morshedi

Polymorphisms in interleukin genes (IL-6 and IL-10) are involved in the pathogenesis of breast cancer. This study investigated polymorphisms in the promoter regions of IL-6 (-174G/C) and IL-10 (-1082G/A) through a case-control study employing 80 female subjects who were pathologically diagnosed with breast cancer. All patients received follow-up care at t.. Read More»

Genet. Mol. Res. 15(1): gmr.15017360

DOI: 10.4238/gmr.15017360

Medical Genetics   Research Article
Spermiotaxonomy of the tribe Rhodniini (Hemiptera, Triatominae)

Authors: A. Ravazi, J. Oliveira, J.A. Rosa, M.T.V. Azeredo-Oliveira and K.C.C. Alevi

The tribe Rhodniini is a monophyletic group composed of 22 species, with 19 in the Rhodnius genus and three in the Psammolestes genus. These insects are morphologically very similar (cryptic species), and new tools are important for investigating the taxonomy of these vectors. Spermiotaxonomy is an important tool in differentiating between related species.. Read More»

Genet. Mol. Res. 15(1): gmr.15017366

DOI: 10.4238/gmr.15017366

Plant Genetics   Research Article
Diversity and genetic parameter estimates for yield and its components in Jatropha curcas L.

Authors: R.G. Freitas, L.A.S. Dias, P.M.R. Cardoso, A.B. Evaristo, M.F. Silva and N.M. Ara�ºjo

Jatropha curcas L. is one of the most promising oilseeds for biodiesel and biokerosene production, but few basic studies or breeding programs have been conducted for the species. We estimated genetic parameters and diversity based on 10 yield traits in 77 half-sib progenies of J. curcas after 52 months in the field, and evaluated correlations between them.. Read More»

Genet. Mol. Res. 15(1): gmr.15017540

DOI: 10.4238/gmr.15017540

Medical Genetics   Research Article
Roles of oxidative DNA damage of bone marrow hematopoietic cells in steroid-induced avascular necrosis of femoral head

Authors: Z.Q. Zhao, R. Bai, W.L. Liu, W. Feng, A.Q. Zhao, Y. Wang, W.X. Wang, L. Sun, L.S. Wu and S.X. Cui

An animal model of steroid-induced avascular necrosis of femoral head (SANFH) was established to investigate the role of oxidative DNA damage of bone marrow hematopoietic cells in SANFH. Forty-five-month-old Japanese white rabbits (male or female, 2.5 ± 0.5 kg) were randomly divided into groups A (methylprednisolone + E.. Read More»

Genet. Mol. Res. 15(1): gmr.15017706

DOI: 10.4238/gmr.15017706

Plant Genetics   Research Article
Repellent effects of various cherry tomato accessions on the two-spotted spider mite Tetranychus urticae Koch (Acari: Tetranychidae)

Authors: T. Lucini, J.T.V. Resende, J.R.F. Oliveira, C.J. Scabeni, A.R. Zeist and N.C.V. Resende

Several studies have been conducted on resistance sources to improve the genetic resistance of farm-grown tomatoes to arthropod pests, including phytophagous mites. In the present study, we evaluate the behavior of the two-spotted spider mite on different cherry tomato accessions to identify possible sources of resistance (rep.. Read More»

Genet. Mol. Res. 15(1): gmr.15017736

DOI: 10.4238/gmr.15017736

Medical Genetics   Research Article
Immune function of nonparenchymal liver cells

Authors: X.K. Xing, H.Y. Wu, H.G. Feng and Z.Q. Yuan

The liver is the human body largest digestive and metabolic organ, and a very important immune organ. This paper discusses the location and morphology of hepatic sinusoidal endothelial cells, dendritic cells, hepatic stellate cells, and Kupffer cells in the liver and their role in regulating immune functions. Therefore, here we provide a preliminary under.. Read More»

Genet. Mol. Res. 15(1): gmr.15018524

DOI: 10.4238/gmr.15018524

Medical Genetics   Research Article
Acrocomia emensis (Arecaceae) genetic structure and diversity using SSR molecular markers

Authors: D.S. Neiva, A.F. Melo J�ºnior, D.A. Oliveira, V.A. Royo, M.M. Brand�£o and E.V. Menezes

Acrocomia emensis, popularly known as the creeping tucum, belongs to the family Arecaceae, and is an oilseed specie of the Brazilian Savannah. The expansion of agricultural activity has rapidly destroyed its natural habitat, leading to a decrease in its population size. Genetic studies can be used to investigate the genetic variability, and may assist wit.. Read More»

Genet. Mol. Res. 15(1): gmr.15017785

DOI: 10.4238/gmr.15017785

Medical Genetics   Research Article
WNT10A polymorphism may be a risk factor for non-syndromic hypodontia

Authors: S.J. Zhang and Z.Z. Wu2

This study was designed to determine whether polymorphisms in the gene wingless-type MMTV integration site family, member 10A (WNT10A) are associated with non-syndromic hypodontia (tooth agenesis). A case-control study was performed involving 129 subjects with sporadic non-syndromic hypodontia (cases) and 218 healthy individuals (controls). DNA was obtain.. Read More»

Genet. Mol. Res. 15(1): gmr.15016033

DOI: 10.4238/gmr.15016033