Table of Contents | Genet. Mol. Res.2016(1)
Interleukin-17 enhances the removal of respiratory syncytial virus in mice by promoting neutrophil migration and reducing interferon-gamma expression
Authors: G. Zhang, K.F. Zhou and Z.H. Lu
The aim of this study was to observe the effect of interleukin (IL)-17 on early immune response and inflammation in the lungs of respiratory syncytial virus (RSV)-infected mice. Specific pathogen-free BALB/c mice were randomly assigned to control, RSV-infected, RSV-infected with phosphate-buffered saline, and RSV-infected + IL-17 intervention groups. The .. Read More»
Genet. Mol. Res. 15(1): gmr.15017002
DOI: 10.4238/gmr.15017002
Branches of the NF-�ºB signaling pathway regulate proliferation of oval cells in rat liver regeneration
Authors: W.M. Zhao, Y.L. Qin, Z.P. Niu, C.F. Chang, J. Yang, M.H. Li, Y. Zhou and C.S. Xu1,
The NF-kB (nuclear factor kB) pathway is involved in the proliferation of many cell types. To explore the mechanism of the NF-kB signaling pathway underlying the oval cell proliferation during rat liver regeneration, the Rat Genome 230 2.0 Array was used to detect expression changes of NF-kB signaling pathway-related genes in .. Read More»
Genet. Mol. Res. 15(1): gmr.15017750
DOI: 10.4238/gmr.15017750
Population structure of jatropha and its implication for the breeding program
Authors: D.N. Santos, J.L. Ferreira, M. Pasqual, A.L. Generoso3, T.A. Setotaw, G.M.A. Can�§ado and W.A. Vendrame
Jatropha (Jatropha curcas L.) has potential as an oilseed crop that requires the development of technology for its exploitation. The objective of this study was to assess the population structure and the genetic diversity in jatropha accessions at a global level using simple sequence repeat (SSR) molecular markers. Jatropha accessions (N = 109) from 10 co.. Read More»
Genet. Mol. Res. 15(1): gmr.15017770
DOI: 10.4238/gmr.15017770
Mitochondrial dysfunction in resveratrol-induced apoptosis in QGY-7701 cells
Authors: J.P. Li, Q. Ma and C.M. Chen
This study aims to evaluate the cytotoxicity of resveratrol on QGY-7701 cells via a cell viability assay, and determine the cytological alterations and damages that result. Resveratrol was found to inhibit QGY-7701 cell growth and decrease their viability in a remarkably dose-dependent manner. Resveratrol exposure also induced an increase in Caspase-3 act.. Read More»
Genet. Mol. Res. 15(1): gmr.15017490
DOI: 10.4238/gmr.15017490
Isolation and characterization of new microsatellite loci in Fenneropenaeus penicillatus
Authors: B.B. Li,2, Z.B. Li1,, Y.F. Ning, J.B. Shangguan, Y.S. Huang, Y. Yuan and X.Q. Mao
Fenneropenaeus penicillatus is one of the major economic shrimp species in China. In this study, 14 novel microsatellite loci were developed using the fast isolation protocol with amplified fragment length polymorphism of sequences containing repeats (FIASCO). Polymorphisms were tested in 30 individuals from a single-wild population. The results showed th.. Read More»
Genet. Mol. Res. 15(1): gmr.15017387
DOI: 10.4238/gmr.15017387
miR-133 inhibits pituitary tumor cell migration and invasion via down-regulating FOXC1 expression
Authors: D.S. Wang, H.Q. Zhang, B. Zhang, Z.B. Yuan, Z.K. Yu, T. Yang, S.Q. Zhang, Y. Liu and X.X. Jia
Many studies have shown that microRNA (miR)-133 functions as a tumor suppressor in a variety of metastatic cancers, including breast cancer, gastric cancer, and liver fibrosis. However, the influence of miR-133 on pituitary tumor malignancy has not yet been reported. The purpose of this study was to explore the role of miR-133.. Read More»
Genet. Mol. Res. 15(1): gmr.15017453
DOI: 10.4238/gmr.15017453
Protective effect of the n-butanol Toona sinensis seed extract on diabetic nephropathy rat kidneys
Authors: W.Z. Li, X.H. Wang, H.X. Zhang, S.M. Mao and C.Z. Zhao
The objective of this study was to observe the protective effect of the n-butyl alcohol phase of Toona sinensis seed extract on the kidneys of diabetic nephropathy (DN) rats and its preliminary mechanism. Male wistar rats were administered a normal or high-fat diet for 1 month. DN rats were divided into a model group and a pet.. Read More»
Genet. Mol. Res. 15(1): gmr.15017403
DOI: 10.4238/gmr.15017403
Effects of Sirtuin 1 on the proliferation and osteoblastic differentiation of periodontal ligament stem cells and stem cells from apical papilla
Authors: Q.-B. Zhang, W. Cao, Y.-R. Liu, S.-M. Cui and Y.-Y. Yan
The function of SIRT1 in the proliferation and osteoblastic differentiation of dental stem cells is unclear. The aim of this study was to assess the roles of SIRT1 in these processes using periodontal ligament stem cells (PDLSCs) and stem cells from apical papilla (SCAPs). A defined concentration of resveratrol, an SIRT1 activ.. Read More»
Genet. Mol. Res. 15(1): gmr.15015234
DOI: 10.4238/gmr.15015234