Table of Contents | Genet. Mol. Res.2016(1)
Role of IL-10 polymorphisms in susceptibility to hepatitis B virus-related hepatocellular carcinoma
Authors: M.W. Peng, S.Q. Lu, J. Liu and C.Y. Dong
We conducted a case-control study to investigate the role of three common single nucleotide polymorphisms of IL-10 (-592G/A, -819T/C, and -1082A/C) in the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). The study included 173 HBV-related HCC patients and 182 healthy controls. A polymerase chain r.. Read More»
Genet. Mol. Res. 15(1): gmr.15017984
DOI: 10.4238/gmr.15017984
Genetic diversity in the germplasm of black pepper determined by EST-SSR markers
Authors: B.D. Wu, R. Fan, L.S. Hu, H.S. Wu and C.Y. Hao
This study aimed to assess genetic diversity in the germplasm of black pepper from around the world using SSR markers from EST. In total, 13 markers were selected and successfully amplified the target loci across the black pepper germplasm. All the EST-SSR markers showed high levels of polymorphisms with an average polymorphis.. Read More»
Genet. Mol. Res. 15(1): gmr.15018099
DOI: 10.4238/gmr.15018099
Expression of Epstein-Barr virus antibodies EA-IgG, Rta-IgG, and VCA-IgA in nasopharyngeal carcinoma and their use in a combined diagnostic assay
Authors: Y. Li, K. Wang, S.K.Yin, H.L. Zheng and D.L. Min
Epstein-Barr virus (EBV) infection is closely associated with nasopharyngeal carcinoma, which can be monitored by the levels of Rta protein antibody IgG (Rta-IgG), early antigen antibody (EA-IgG), and viral capsid antibody (VCA-IgA). In the present study, we investigated the serum levels of Rta-IgG, EA-IgG, and VCA-IgA in naso.. Read More»
Genet. Mol. Res. 15(1): gmr.15017368
DOI: 10.4238/gmr.15017368
Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene
Authors: L.J. Duan and X.D. Wang
This study aimed to explore correlations between haplotypes of the angiotensin II receptor type 1 (AGTR1) gene and coronary heart disease (CHD). In total, 204 patients with CHD and 206 healthy controls were genotyped using denaturing high-performance liquid chromatography between 2008 and 2014. Five polymorphic loci were found.. Read More»
Genet. Mol. Res. 15(1): gmr.15017457
DOI: 10.4238/gmr.15017457
All-trans retinoic acid prevents the development of type 1 diabetes by affecting the levels of interferon gamma and interleukin 4 in streptozotocin-induced murine diabetes model
Authors: Y. Wang, Y.J. Zhong, Y.Y. Wang, J. Xing and Z.M. Wang
The aim of this study was to explore the molecular mechanism by which all-trans retinoic acid (ATRA) prevents type 1 diabetes mellitus (T1DM). Fifty ICR mice were randomly assigned to three groups: prevention group [N = 20; mice received 10 mg/kg ATRA daily for 5 days and then 60 mg/kg streptozotocin (STZ) for 5 days]; diabeti.. Read More»
Genet. Mol. Res. 15(1): gmr.15017522
DOI: 10.4238/gmr.15017522
Cytochemical characteristics of blood cells from Brazilian tortoises (Testudines: Testudinidae)
Authors: G.S. Martins, K.C.C. Alevi, M.T.V. Azeredo-Oliveira and C.R. Bonini-Domingos
The hematology of wild and captive animals is essential for obtaining details about species and represents a simple method of diagnosing disease and determining prognosis. Few studies have described the morphology of chelonian blood cells, which are more common in sea and freshwater turtle species. Thus, in order to further ou.. Read More»
Genet. Mol. Res. 15(1): gmr.15017549
DOI: 10.4238/gmr.15017549
A 425 T>C polymorphism in complement C7 association with resistance to Aeromonas hydrophila in grass carp
Authors: Y.B. Shen, J.B. Zhang, J.J. Fu, X.Y. Xu, J.L. Li R.Q. Wang and Y.F. Xuan
Aeromonas hydrophila, a widespread bacterium in the aquatic environment, causes hemorrhagic septicemia in fish. In the last decade, the disease has caused mass mortalities and tremendous economic loss in cultured fish. The complement component C7 is a terminal component of complement that interacts in a sequence of polymerizat.. Read More»
Genet. Mol. Res. 15(1): gmr.15014526
DOI: 10.4238/gmr.15014526
Association of the programmed cell death-1 PD1.5 C>T polymorphism with cervical cancer risk in a Chinese population
Authors: X.F. Li, X.Q. Jiang, J.W. Zhang and Y.J. Jia
The association of the programmed cell death-1 PD1.5 C>T polymorphism with cervical cancer risk has not been investigated. In this hospital-based case-control study, we analyzed 256 patients with cervical cancer and 250 healthy controls. Pearson chi-square test was used to examine differences in the distribution of genotype.. Read More»
Genet. Mol. Res. 15(1): gmr.15016357
DOI: 10.4238/gmr.15016357