Table of Contents | Genet. Mol. Res.2016(1)
Genome sequencing and systems biology analysis of a lipase-producing bacterial strain
Authors: N. Li*, D.D. Li*, Y.Z. Zhang, Y.Z. Yuan, H. Geng, L. Xiong and D.L. Liu
Lipase-producing bacteria are naturally-occurring, industrially-relevant microorganisms that produce lipases, which can be used to synthesize biodiesel from waste oils. The efficiency of lipase expression varies between various microbial strains. Therefore, strains that can produce lipases with high efficiency must be screened, and the conditions of lipas.. Read More»
Genet. Mol. Res. 15(1): gmr.15017331
DOI: 10.4238/gmr.15017331
A diagnostic kit for the enteroviruses Coxsackie A6 and A10
Authors: X.Y. Zhang1, X. Yao2, Z.W. Chen3, X.H. Jiang4, N.H. Xie3, C.Y. Zhang5 and Z.H. Guan5
Recently, there has been an upward trend in the occurrence of hand-foot-mouth disease, which is correlated with Coxsackie A6 and A10 infections. Although two separate diagnostic reagents are available for these two viral strains, the protocol and diagnosis efficiency still need to be improved. More importantly, as co-infection with these viruses is common.. Read More»
Genet. Mol. Res. 15(1): gmr.15017431
DOI: 10.4238/gmr.15017431
Roles of osteocyte apoptosis in steroid-induced avascular necrosis of the femoral head
Authors: R. Bai1*, W. Feng2*, W.L. Liu1, Z.H.Q. Zhao1, A.Q. Zhao1, Y. Wang1, W.X. Wang1, L. Sun1, L.S.H. Wu1 and S.H.X. Cui1
An animal model of steroid-induced avascular necrosis of the femoral head (SANFH) was established to investigate the roles of osteocyte apoptosis in this process. Forty five-month-old male and female Japanese white rabbits were randomly divided into groups A (hormone + endotoxin), B (hormone alone), C (endotoxin alone), and D (blank control). Animals were.. Read More»
Genet. Mol. Res. 15(1): gmr.15017529
DOI: 10.4238/gmr.15017529
Gene expression changes in chicken NLRC5 signal pathway associated with in vitro avian leukosis virus subgroup J infection
Authors: L.L. Qiu1, L. Xu1, X.M. Guo1, Z.T. Li1, F. Wan1, X.P. Liu2, G.H. Chen1 and G.B. Chang1
Nucleotide-binding oligomerization domain-like receptors (NLRs) play a key role in the innate immune response as pattern-recognition receptors. However, the role of NLRC5, which is a member of the NLR family, in NF-κB activation and MHC-I expression remains debatable. Infection with the J group avian leukosis virus (ALV-J) can result in immunosuppre.. Read More»
Genet. Mol. Res. 15(1): gmr.15017640
DOI: 10.4238/gmr.15017640
Mechanism of SEMA3B gene silencing and clinical significance in glioma
Authors: C.H. Pang, W. Du, J. Long and L.J. Song
The aim of the current study was to explore mechanisms of SEMA3B gene expression and its clinical significance in glioma, and provide a theoretical foundation for investigating individualized treatment in glioma. Paraffin-embedded tissues from 43 patients with a confirmed clinical diagnosis of glioma following neurosurgery at the First Affiliated Hospital.. Read More»
Genet. Mol. Res. 15(1): gmr.15017664
DOI: 10.4238/gmr.15017664
QTL mapping of soybean oil content for marker-assisted selection in plant breeding program
Authors: D.C. Leite1, J.B. Pinheiro2, J.B. Campos2, A.O. Di Mauro1 and S.H. Un�ªda-Trevisoli1
The present study was undertaken to detect and map the quantitative trait loci (QTL) related to soybean oil content. We used 244 progenies derived from a bi-parental cross of the Lineage 69 (from Universidade Estadual Paulista “Júlio de Mesquita Filho”/Faculdade de Ciências Agrárias e Veterinárias - Breeding Program).. Read More»
Genet. Mol. Res. 15(1): gmr.15017685
DOI: 10.4238/gmr.15017685
Cytogenetic findings in patients diagnosed with breast cancer having undergone adjuvant chemotherapy regimens
Authors: P.A. Ko��ar, M. Ko�§er, D.A. ��elik and N. ��z�§elik
The aim of the present study was to investigate DNA damage in peripheral blood lymphocytes of breast cancer (BC) patients before and after administration of chemotherapy. We analyzed the frequency of sister chromatid exchange (SCE), occurrence of micronuclei (MN), and lymphocyte proliferation rate index (PRI) as cytogenetic markers in 28 female BC patient.. Read More»
Genet. Mol. Res. 15(1): gmr.15017699
DOI: 10.4238/gmr.15017699
Cytotoxic and immunomodulatory effects of Ebenus boissieri Barbey on breast cancer cells
Authors: N. Imir, E. Aydemir E. Simsek, R.S. Gokturk, E. Yesilada and K. Fiskin
We aimed to determine the cytotoxic and immunomodulatory effects of hydroalcoholic extracts of the roots and aerial parts of Ebenus boissieri (EB) on breast cancer MDA-MB231 cells and the non-cancerous human embryonic kidney cell line, 293T. Cell viability was determined by MTT assay, trypan blue exclusion, and Live/Dead Viabi.. Read More»
Genet. Mol. Res. 15(1): gmr.15017766
DOI: 10.4238/gmr.15017766