Y. Liu
Corrigendum: Correlation between adiponectin (ADPN) and hemorrhagic shock in mice - Genet. Mol. Res. 15 (1): gmr.15017037 (DOI: 10.4238/gmr.15017037)
-.. Read More»
Genet. Mol. Res. 16(2): gmr160270371
DOI: 10.4238/gmr160270371
Novel representation of RNA secondary structure used to improve prediction algorithms
We propose a novel representation of RNA secondary structure for a quick comparison of different structures. Secondary structure was viewed as a set of stems and each stem was represented by two values according to its position. Using this representation, we improved the comparative sequence analysis method results and the minimum free-energy model. In the comparati.. Read More»
Genet. Mol. Res. 10(3): vol10-3gmr1181
DOI: 10.4238/vol10-3gmr1181
Deep RNA sequencing elucidates microRNA-regulated molecular pathways in ischemic cardiomyopathy and nonischemic cardiomyopathy
Deregulation of cardiac miRNA gene-regulatory networks is a feature of different heart diseases, including ischemic (ICM) and nonischemic (NICM) cardiomyopathy. Here, based on the paired miRNA and mRNA expression profiles in ICM and NICM, we identified the differentially expressed miRNAs and mRNAs and the expression signatures distinguishing ICM/NICM from control sa.. Read More»
Genet. Mol. Res. 15(2): gmr.15027465
DOI: 10.4238/gmr.15027465
Post-surgical treatment of a patient with ectopic pheochromocytoma
We report here the course and treatment of a patient with ectopic pheochromocytoma. The patient was cured after treatment with respiratory and circulatory support, multiple-organ protection, and continuous renal replacement therapy (CRRT) for approximately 2 weeks. After misdiagnosis, a patient with ectopic pheochromocytoma who is being treated should undergo aggressive fluid supplementation an.. Read More»
Genet. Mol. Res. 14(1): 2015.March.20.25
DOI: 10.4238/2015.March.20.25
Genetic variations in MOV10 and CACNB2 are associated with hypertension in a Chinese Han population
Human hypertension is a complex, multifactorial disease. Multiple variants associated with hypertension have been identified in the large numbers of genome-wide association studies, meta-analysis, and case-control studies. The present study investigated the association between the single nucleotide polymorphisms (SNPs) of five candidate genes and the susceptibility and prognosis of hypertension.. Read More»
Genet. Mol. Res. 12(4): 2013.December.4.9
DOI: 10.4238/2013.December.4.9
Inhibitory effect of microRNA-27b on interleukin 17 (IL-17)-induced monocyte chemoattractant protein-1 (MCP1) expression
We investigated the effect of microRNA-27b (miR-27b), a gene expression regulatory factor, on the expression of monocyte chemoattractant protein-1 (MCP1) stimulated by interleukin 17 (IL-17). After IL-17 had been added to H9C2 cardiomyocytes, an miR-27b mimic was transfected into the H9C2 cells. The mRNA expression levels of miR-27b and MCP1 in the H9C2 cells were d.. Read More»
Genet. Mol. Res. 15(2): gmr.15027784
DOI: 10.4238/gmr.15027784
A potential indicator of denervated muscle atrophy: the ratio of myostatin to follistatin in peripheral blood
Myostatin is a secreted negative regulator of muscle mass, and follistatin antagonizes the function of several members of the TGF-b family, including myostatin. Previously, myostatin expression was found to be closely associated with atrophy of the gastrocnemius muscle, showing a linear correlation, after sciatic nerve injury. In this study, we investigated the poss.. Read More»
Genet. Mol. Res. 10(4): 2011.October.21.7
DOI: 10.4238/2011.October.21.7
imDC: an ensemble learning method for imbalanced classification with miRNA data
Imbalances typically exist in bioinformatics and are also common in other areas. A drawback of traditional machine learning methods is the relatively little attention given to small sample classification. Thus, we developed imDC, which uses an ensemble learning concept in combination with weights and sample misclassification information to effectively classify imbalanced data. Our method showed.. Read More»
Genet. Mol. Res. 14(1): 2015.January.15.15
DOI: 10.4238/2015.January.15.15
Association between IL2/IL21 and SH2B3 polymorphisms and risk of celiac disease: a meta-analysis
Celiac disease (CD) is a common autoimmune disorder characterized by heightened immunological response to ingested gluten. Certain gene polymorphisms of IL2/IL21 (rs6822844 and rs6840978) and SH2B3 (rs3184504) may influence susceptibility to CD, although the effects remain unclear. We performed a meta-analysis of the associations between rs6822844, rs6840978, and rs3184504 polymorphisms and CD .. Read More»
Genet. Mol. Res. 14(4): 2015.October.26.19
DOI: 10.4238/2015.October.26.19
A novel FBN1 heterozygous mutation identified in a Chinese family with autosomal dominant Marfan syndrome
The purpose of this study was to identify the clinical features and mutations in the fibrillin-1 gene (FBN1) in a large Chinese family with autosomal dominant Marfan syndrome (MFS). Seventeen members from a Chinese family of 4 generations were included in the study. All members underwent complete ophthalmic examination. Molecular genetic analysis was performed on all subjects. All exons of FBN1.. Read More»
Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.27.27
DOI: http://dx.doi.org/10.4238/2015.April.27.27
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Citations : 56184
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