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X. Gong

Publications of : X. Gong
Human Genetics   Research Article

Establishment of a blue light damage model of human retinal pigment epithelial cells in vitro

    G. Su, S.J. Cai, X. Gong, L.L. Wang, H.H. Li and L.M. Wang

To establish a blue-light damage model of human retinal pigment epithelium (RPE). Fourth-generation human RPE cells were randomly divided into two groups. In group A, cells were exposed to blue light (2000 ± 500 lux) for 0 (control), 3, 6, 9, and 12 h, and cell culture was stopped after 12 h. In group B, cells were exposed to blue light at the same intensity .. Read More»

Genet. Mol. Res. 15(2): gmr.15028092

DOI: 10.4238/gmr.15028092

Medical Genetics   Research Article

Effect of morphine preconditioning in the delayed phase on the expression of p38 mitogen-activated protein kinase in a rabbit model of myocardial ischemia-reperfusion injury

    K. Ran, Z.X. Gong, D.L. Yang, Y.T. Chang, K.M. Duan and Y.W. Ou

This study aimed to investigate the protective effects of delayed morphine preconditioning on myocardial ischemia-reperfusion injury. We randomly divided 30 rabbits into three groups with 10 rabbits in each group as follows: sham operation group (C group), ischemia-reperfusion group (I/R group), and morphine pretreatment group (M group). Rabbits in C Group received left coronary without blockin.. Read More»

Genet. Mol. Res. 14(2): 2015.June.18.7

DOI: 10.4238/2015.June.18.7

Animal Genetics   Research Article

Correlation between adiponectin and hemorrhagic shock in mice

    X. Gong, Y. Liu, S. Yao, J.F. Zheng, F. Wan, X.D. Xiang and X.P. Chai

The aim of this study was to explore the relationship between adiponectin (ADPN) and hemorrhagic shock (HS) and the recovery after HS. This is significant for further understanding of the pathophysiological processes of HS and the development of better treatments. In total, 72 male C57BL/6 mice were assigned randomly to three groups: control, HS, and recovery (N = 24). The HS mouse model was co.. Read More»

Genet. Mol. Res. 15(1): gmr.15017037

DOI: 10.4238/gmr.15017037

Bioinformatics   Research Article

Efficient detection of the V600E mutation of the BRAF gene in papillary thyroid carcinoma using multiplex allele-specific polymerase chain reaction combined with denaturing high-performance liquid chromatography

    R.X. Gong1, Y.P. Gong1, J. Yang1, T. Wei1, J. Li-Ling2,3 and J.Q. Zhu1

Mutations in the V-raf murine sarcoma viral oncogene homolog B1 gene (BRAF) play an important role in the pathogenesis of papillary thyroid cancer (PTC). In this study, a BRAF V600E mutation was detected in formalin-fixed and paraffin-embedded PTC samples using multiplex allele-specific polymerase chain reaction and denaturing high-performance liquid chromatography. The sensitivity of the assay.. Read More»

Genet. Mol. Res. 12(4): 2013.October.24.11

DOI: 10.4238/2013.October.24.11