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Publications of : H.W. Cui
Human Genetics   Research Article

Clinical significance and expression of PUMA, MCL-1, and p53 in human renal cell carcinoma and para-carcinoma tissues

We investigated the expression level of p53 upregulated modulator of apoptosis (PUMA), myeloid cell leukemia-I (MCL-1), and p53 in renal cell carcinoma (RCC) and para-carcinoma tissues, as well as their clinical significance. The expression levels of PUMA, MCL-1, and p53 in RCC and para-carcinoma tissues were measured using immunohistochemical and quantitative real-.. Read More»

Genet. Mol. Res. 16(3): gmr16039278

DOI: 10.4238/gmr16039278

Human Genetics   Research Article

Association between peroxisome proliferator-activated receptor gamma coactivator-1 alpha polymorphism and hypertension in Mongolians in Inner Mongolia

    X.L. Su, H.R. Dong, M.R. Yan, H.W. Cui, L. Yang and F.Q. Han

We investigated a possible association of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) Gly482Ser polymorphism with hypertension in Mongolians in Inner Mongolia. A total of 787 subjects were enrolled randomly, including 390 hypertension patients and 397 healthy controls. Triglycerides, cholesterol, and fasting plasma glucose wer.. Read More»

Genet. Mol. Res. 10(4): 2011.December.12.2

DOI: 10.4238/2011.December.12.2

Human Genetics   Research Article

Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China

    Z.F. Yang, H.W. Cui, T. Hasi, S.Q. Jia, M.L. Gong and X.L. Su

We examined the distribution of major allelic variants of CYP2C9 and CYP2C19 in the Mongolian population of China and compared it with that of other populations. The polymorphisms of CYP2C9 (including the CYP2C9*1, CYP2C9*2 and CYP2C9*3 alleles) and CYP2C19 (including the CYP2C19*1, CYP2C19*2 and CYP2C19*3 alleles) were analyzed in 280 healthy unrelated Chinese Mong.. Read More»

Genet. Mol. Res. 9(3): vol9-3gmr938

DOI: 10.4238/vol9-3gmr938

Medical Genetics   Research Article

Association of a CYP4A11 polymorphism and hypertension in the Mongolian and Han populations of China

    J.Q. Liang, M.R. Yan, L. Yang, Q. Suyila, H.W. Cui and X.L. Su

Human cytochrome P450 4A11 (CYP4A11) plays a role in the regulation of blood pressure through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE). We therefore investigated the association between a CYP4A11 polymorphism (rs9333025) with hypertension in the Mongolian and Han ethnic groups. We studied 514 Mongolians in a pastoral area, in.. Read More»

Genet. Mol. Res. 13(1): 2014.January.21.20

DOI: 10.4238/2014.January.21.20

Human Genetics   Research Article

High methylation of the SEPT9 gene in Chinese colorectal cancer patients

    X.L. Su, Y.F. Wang, S.J. Li, F. Zhang and H.W. Cui

Methylation of the septin 9 gene (SEPT9) occurs in higher frequency in colorectal cancer (CRC) compared to control samples, which suggests that SEPT9 methylation is a useful biomarker for screening CRC. However, the methylation status of SEPT9 in Chinese CRC patients is scarcely reported. In the present study, SEPT9 methylation was tested in CRC tissues obtained fro.. Read More»

Genet. Mol. Res. 13(2): 2014.January.17.5

DOI: 10.4238/2014.January.17.5

Human Genetics   Research Article

Association between PPARĪ³2 Pro12Ala polymorphism and myocardial infarction and obesity in Han Chinese in Hohhot, China

    L.P. Wang L.R. Zhao H.W. Cui M.R. Yan L. Yang X.L. Su

Activation of the peroxisome proliferator-activated receptor g (PPARg) improves insulin sensitivity and inhibits atherosclerosis. Whether PPARg2 Pro12Ala polymorphism affects myocardial infarction is not clearly understood. We investigated a possible association of PPARg2 Pro12Ala polymorphism with obesity and myocardial infarction in Han Chinese in Hohhot, Inner Mongolia, China. We included 12.. Read More»

Genet. Mol. Res. 11(3): 2012.May.18.13

DOI: 10.4238/2012.May.18.13

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