Microbial Genetics
Association between ERCC1 and ERCC2 gene polymorphisms and chemotherapy response and overall survival in osteosarcoma
Authors: Z.H. Cao, H.P. Yin, N. Jiang and B. Yu
We aimed to evaluate the influence of four SNPs in ERCC1 and ERCC2 on the response to cisplatin-based treatment and on clinical outcome in patients with osteosarcoma. We identified 186 patients with osteosarcoma diagnosed between April 2009 and April 2011 who were eligible for inclusion in our study. Genotyping of ERCC1 rs11615, rs3212986, and rs2298881; .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.21
- DOI:
- 10.4238/2015.August.21.21
Cloning and characterization of DELLA genes in Artemisia annua
Authors: Q. Shen, J. Cui, X.Q. Fu, T.X. Yan and K.X. Tang
Gibberellins (GA) are some of the most important phytohormones involved in plant development. DELLA proteins are negative regulators of GA signaling in many plants. In this study, the full-length cDNA sequences of three DELLA genes were cloned from Artemisia annua. Phylogenetic analysis revealed that AaDELLA1 and AaDELLA2 were located in the same cluster,.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.10
- DOI:
- 10.4238/2015.August.21.10
Identification and analysis of the TIFY gene family in Gossypium raimondii
Authors: D.H. He, Z.P. Lei, B.S. Tang, H.Y. Xing, J.X. Zhao and Y.L. Jing
The highly conserved TIFY domain is included in the TIFY protein family of transcription factors, which is important in plant development. Here, 28 TIFY family genes were identified in the Gossypium raimondii genome and classified into JAZ (15 genes), ZML (8), PPD (3), and TIFY (2). The normal (TIF[F/Y]XG) motif was dominant in the TIFY family, excluding .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.19
- DOI:
- 10.4238/2015.August.21.19
Differential expression of TLP, ERF1, and R2R3MYB in annual Medicago species under salinity conditions
Authors: F. Gharaghani, F. Rafiei, N. Mirakhorli and E. Ebrahimie
The present study was conducted to evaluate the responses of three annual Medicago species (M. truncatula, M. laciniata, and M. polymorpha) to salinity. We analyzed publicly available microarray data in NCBI pertaining to salinity-response genes in M. truncatula. Our data search identified Tubby C2 (TLP) and ethylene responsive transcription factor 1 (ERF.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.22
- DOI:
- 10.4238/2015.August.21.22
Investigation of genes in chronic and acute morphine-treated mice using microarray datasets
Authors: L. Ding, J.L. Zhang, S.H. Yu and L.F. Sheng
Morphine is a psychoactive medication that is used as a standard analgesic treatment to relieve pain in clinics. Many patients rely on chronic or acute treatment of morphine to treat pain. However, morphine is a narcotic and has a reverse effect when inappropriately used. Therefore, it is necessary to study chronic and acute morphine treatment to improve .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.3
- DOI:
- 10.4238/2015.August.28.3
Cloning and stress response analysis of the PeDREB2A and PeDREB1A genes in moso bamboo (Phyllostachys edulis)
Authors: H.L. Wu, L. Li, Z.C. Cheng, W. Ge, J. Gao and X.P. Li
Moso bamboo is a large woody bamboo with the highest ecological, economic, and cultural value among all bamboos in Asia. However, environmental stress influences its growth and development and limits its geographic distribution. Therefore, improving its resistance to environmental stress is extremely important. Dehydration responsive element binding (DREB.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.4
- DOI:
- 10.4238/2015.August.28.4
Genomic characterization and sequence diversity of the ?²2-microglobulin gene in the miiuy croaker, Miichthys miiuy
Authors: Y.N. Sun, X.R. Su, T.J. Xu and T.W. Li
β2-Microglobulin (β2m) is related to major histocompatibility complex class I alpha chains, and forms cell-surface glycoproteins that mediate a variety of functions in immune defense. In general, β2m has no isoforms and is not polymorphic in higher vertebrates, but polymorphisms between different alleles have been found in some fish species.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.9
- DOI:
- 10.4238/2015.August.28.9
Investigation of single nucleotide polymorphisms in phosphodiesterase 4D gene in Mongol and Han patients with ischemic stroke in Inner Mongolia
Authors: J.P. Shi, W.D. Chen, J.Q. Zhou, M.M. Xue, F. Xue, H.Z. Li and Z.P. Xu
We investigated single nucleotide polymorphisms (SNP) at 87 sites of the phosphodiesterase 4D (PDE4D) gene in Mongol and Han patients with ischemic stroke in Inner Mongolia. SNPs in 226 patients with ischemic stroke (case group, 110 Mongol patients, 116 Han patients) and 220 patients without neurological disease (control group, 102 Mongol patients, 118 Ha.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.13
- DOI:
- 10.4238/2015.August.28.13
Whole-transcriptome sequencing of Pinellia ternata using the Illumina platform
Authors: X. Huang, Y. Jing, D.J. Liu, B.Y. Yang, H. Chen and M. Li
Pinelliae rhizoma is the dried tuber of Pinellia ternata (Thunb.) Breit., and has been used for thousands of years as a traditional Chinese medicine. However, its genomic background is little known. With the development of high-throughput genomic sequencing, it is now easy and cheap to obtain genomic information. In this study.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028062
- DOI:
- 10.4238/gmr.15028062
Populations of Erythrina velutina Willd. at risk of extinction
Authors: M.F.V. Melo, L.O. Gon?§alves, A.R.C. Rabbani, S.V. ?lvares-Carvalho, J.B. Pinheiro, M.I. Zucchi and R. Silva-Mann
The goal of this study was to characterize the structure of two natural populations of the coral tree using RAPD and ISSR markers. The study evaluated all individuals in two different areas in the northeastern region of Brazil: the first was in the riparian area, 10 km x 100 m along the edge of the lower São Francisco River, and the second was in t.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.15
- DOI:
- 10.4238/2015.August.28.15